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Completed No phase listed Observational

Stopping and Restarting Anti-HIV Drugs in Children and Adolescents With Low Blood Levels of HIV

ClinicalTrials.gov ID: NCT00016783

Public ClinicalTrials.gov record NCT00016783. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 4:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Intensification of HIV-Specific CD4 and CD8 Activity by Cycling Highly Active Antiretroviral Therapy (HAART) in Pediatric/Adolescent Patients With Less Than 50 HIV RNA Copies/ml

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Some patients taking anti-HIV drugs as part of highly active antiretroviral therapy (HAART) do not show any HIV in the blood; however, some HIV will remain hidden in the body and, if the drugs are stopped, will return to the blood. The purpose of this study is to determine if short periods of stopping HAART increase the activity of CD8 and CD4 cells (cells of the immune system that fight infection), if repeated stopping of these drugs for longer periods of time and restarting them will increase effectiveness of HAART, and if the increased immune system activity as a result of stopping treatment leads to lower levels of HIV over time.

Study identification

NCT ID
NCT00016783
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
39 participants

Conditions and interventions

Conditions

Interventions

Not listed

Eligibility (public fields only)

Age range
2 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Sep 30, 2006
Last update posted
Oct 6, 2013

Ends 2006

United States locations

U.S. sites
16
U.S. states
10
U.S. cities
14
Facility City State ZIP Site status
Los Angeles County - USC Med Ctr Los Angeles California 90033
Children's Hosp of Denver Denver Colorado 802181088
Howard Univ Hosp Washington D.C. District of Columbia 20060
Univ of Miami (Pediatric) Miami Florida 33161
Chicago Children's Memorial Hosp Chicago Illinois 606143394
Johns Hopkins Hosp - Pediatric Baltimore Maryland 21287
Children's Hosp of Boston Boston Massachusetts 021155724
Univ of Medicine & Dentistry of New Jersey / Univ Hosp Newark New Jersey 071032714
St. Lukes/Roosevelt Hosp Ctr New York New York 10025
Columbia Presbyterian Med Ctr New York New York 10032
Harlem Hosp Ctr New York New York 10037
University of Rochester Medical Center Rochester New York 14642-0001
State Univ of New York at Stony Brook Stony Brook New York 117948111
SUNY Health Sciences Ctr at Syracuse / Pediatrics Syracuse New York 13210
Bronx Lebanon Hosp Ctr The Bronx New York 10457
Texas Children's Hosp / Baylor Univ Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00016783, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 6, 2013 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00016783 live on ClinicalTrials.gov.

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