ClinicalTrials.gov record
S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma
ClinicalTrials.gov ID: NCT00017147
Public ClinicalTrials.gov record NCT00017147. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Study of Radiation Therapy (RT) and O6-Benzylguanine (O6-BG) Plus BCNU Versus RT and BCNU Alone for Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. O6-benzylguanine may help carmustine kill more tumor cells by making tumor cells more sensitive to the drug. It is not yet known whether radiation therapy and carmustine are more effective with or without O6-benzylguanine. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus carmustine with or without O6-benzylguanine in treating patients who have newly diagnosed glioblastoma multiforme or gliosarcoma.
Study identification
- NCT ID
- NCT00017147
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 183 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2001 (Type not available)
- Primary completion
- May 2006 (Actual)
- Completion
- Nov 2012 (Actual)
- Last update posted
- Jan 30, 2013
2001 – 2012
United States locations
- U.S. sites
- 163
- U.S. states
- 27
- U.S. cities
- 108
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Regional Hospital Cancer Center | Anchorage | Alaska | 99508 | — |
| Banner Good Samaritan Medical Center | Phoenix | Arizona | 85006 | — |
| CCOP - Western Regional, Arizona | Phoenix | Arizona | 85006 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Banner Thunderbird Medical Center | Phoenix | Arizona | 85306 | — |
| North Bay Cancer Center | Fairfield | California | 94533 | — |
| Memorial Hospital Cancer Center | Colorado Springs | Colorado | 80909 | — |
| St. Anthony Central Hospital | Denver | Colorado | 80204 | — |
| University of Colorado Cancer Center at University of Colorado Health Sciences Center | Denver | Colorado | 80217-3364 | — |
| North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| McKee Medical Center | Loveland | Colorado | 80539 | — |
| St. Anthony North Hospital | Westminster | Colorado | 80030 | — |
| Exempla Lutheran Medical Center | Wheat Ridge | Colorado | 80033 | — |
| West Florida Cancer Institute at West Florida Hospital - Pensacola | Pensacola | Florida | 32514 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342 | — |
| Northside Hospital Cancer Center | Atlanta | Georgia | 30342 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| WellStar Cobb Hospital | Austell | Georgia | 30106 | — |
| Charles B. Eberhart Cancer Center at DeKalb Medical Center | Decatur | Georgia | 30033 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Gwinnett Medical Center | Lawrenceville | Georgia | 30045 | — |
| Kennestone Cancer Center at Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Southern Regional Medical Center | Riverdale | Georgia | 30274 | — |
| Hematology Oncology Associates of Eastern Idaho | Idaho Falls | Idaho | 83404 | — |
| Saint Anthony's Hospital at Saint Anthony's Health Center | Alton | Illinois | 62002 | — |
| University of Illinois at Chicago Cancer Center | Chicago | Illinois | 60612 | — |
| Veterans Affairs Medical Center - Chicago Westside Hospital | Chicago | Illinois | 60612 | — |
| Decatur Memorial Hospital Cancer Care Institute | Decatur | Illinois | 62526 | — |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | — |
| Regional Cancer Center at Memorial Medical Center | Springfield | Illinois | 62781-0001 | — |
| St. Francis Hospital and Health Centers | Beech Grove | Indiana | 46107 | — |
| Genesis Regional Cancer Center at Genesis Medical Center | Davenport | Iowa | 52803 | — |
| Genesis Medical Center - West Campus | Davenport | Iowa | 52804 | — |
| Cancer Center of Kansas - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas, P.A. - El Dorado | El Dorado | Kansas | 67042 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Kansas | 64128 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Cancer Center of Kansas - Kingman | Kingman | Kansas | 67068 | — |
| Southwest Medical Center | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas, P.A. - Parsons | Parsons | Kansas | 67357 | — |
| Pratt Cancer Center of Kansas | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas - Salina | Salina | Kansas | 67042 | — |
| Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Stormont-Vail Cancer Center | Topeka | Kansas | 66604 | — |
| St. Francis Comprehensive Cancer Center | Topeka | Kansas | 66606 | — |
| Cancer Center of Kansas - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Womens Health | Wichita | Kansas | 67203 | — |
| Cancer Center of Kansas, P.A. | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, P.A. - Wichita | Wichita | Kansas | 67214 | — |
| CCOP - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Winfield | Winfield | Kansas | 67156 | — |
| Baton Rouge General Regional Cancer Center | Baton Rouge | Louisiana | 70806 | — |
| Mary Bird Perkins Cancer Center - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Medical Center of Louisiana - New Orleans | New Orleans | Louisiana | 70112 | — |
| Battle Creek Health System Cancer Care Center | Battle Creek | Michigan | 49017 | — |
| Mecosta County General Hospital | Big Rapids | Michigan | 49307 | — |
| CCOP - Grand Rapids | Grand Rapids | Michigan | 49503 | — |
| Lacks Cancer Center at Saint Mary's Mercy Medical Center | Grand Rapids | Michigan | 49503 | — |
| Spectrum Health Cancer Care - Butterworth Campus | Grand Rapids | Michigan | 49503 | — |
| Metropolitan Hospital | Grand Rapids | Michigan | 49506 | — |
| Holland Community Hospital | Holland | Michigan | 49423 | — |
| Hackley Hospital | Muskegon | Michigan | 49443 | — |
| Northern Michigan Hospital | Petoskey | Michigan | 49770 | — |
| William Beaumont Hospital - Royal Oak Campus | Royal Oak | Michigan | 48073 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| St. Francis Medical Center | Cape Girardeau | Missouri | 63701 | — |
| Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital | Gape Girardeau | Missouri | 63701 | — |
| Freeman Cancer Institute at Freeman Health System | Joplin | Missouri | 64804 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| St. John's Regional Health Center | Springfield | Missouri | 65804 | — |
| Hulston Cancer Center at Cox Medical Center South | Springfield | Missouri | 65807 | — |
| CCOP - St. Louis-Cape Girardeau | St Louis | Missouri | 63141 | — |
| David C. Pratt Cancer Center at St. John's Mercy | St Louis | Missouri | 63141 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Deaconess Billings Clinic - Downtown | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| St. Vincent Healthcare | Billings | Montana | 59101 | — |
| Deaconess Billings Clinic Cancer Center | Billings | Montana | 59107 | — |
| Bozeman Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Internal Medicine Associates of Bozeman | Bozeman | Montana | 59715 | — |
| St. James Community Hospital | Butte | Montana | 59701 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Sletten Regional Cancer Institute | Great Falls | Montana | 59405 | — |
| St. Peter's Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology, PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology | Kalispell | Montana | 59901 | — |
| Eastern Montana Cancer Center | Miles City | Montana | 59301 | — |
| Community Medical Center | Missoula | Montana | 59801 | — |
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | 59802 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59802 | — |
| Good Samaritan Health Systems | Kearney | Nebraska | 68847 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte | North Carolina | 28233 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 54601 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Riverside Methodist Hospital Cancer Care | Columbus | Ohio | 43214 | — |
| CCOP - Columbus | Columbus | Ohio | 43215 | — |
| Grant Riverside Cancer Services | Columbus | Ohio | 43215 | — |
| Mount Carmel West Hospital | Columbus | Ohio | 43222 | — |
| Doctors Hospital at Ohio Health | Columbus | Ohio | 43228 | — |
| Grandview Hospital | Dayton | Ohio | 45405 | — |
| Good Samaritan Hospital | Dayton | Ohio | 45406 | — |
| David L. Rike Cancer Center at Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Samaritan North Cancer Care Center | Dayton | Ohio | 45415 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| CCOP - Dayton | Dayton | Ohio | 45429 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Community Oncology Group - Independence | Independence | Ohio | 44131 | — |
| Charles F. Kettering Memorial Hospital | Kettering | Ohio | 45429 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Strecker Cancer Center at Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Middletown Regional Hospital | Middletown | Ohio | 45044 | — |
| Licking Memorial Cancer Care Program at Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Mercy Medical Center Oncology Unit | Springfield | Ohio | 45504 | — |
| Community Hospital of Springfield and Clark County | Springfield | Ohio | 45505 | — |
| UVMC Cancer Care Center at Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Mount Carmel Cancer Services at Mount Carmel St. Ann's Hospital | Westerville | Ohio | 43081 | — |
| Cleveland Clinic - Wooster | Wooster | Ohio | 44691 | — |
| Ruth G. McMillan Cancer Center at Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Genesis - Good Samaritan Hospital | Zanesville | Ohio | 43701 | — |
| Legacy Mount Hood Medical Center | Glesham | Oregon | 97030 | — |
| Providence Milwaukie Hospital | Milwaukie | Oregon | 97222 | — |
| Legacy Good Samaritan Hospital & Medical Center Comprehensive Cancer Center | Portland | Oregon | 97210 | — |
| Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Institute of Oncology at Vilnius University | Portland | Oregon | 97227 | — |
| Salem Hospital Regional Cancer Center | Salem | Oregon | 97309 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center | Kingsport | Tennessee | 37660 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| Wilford Hall Medical Center | Lackland Air Force Base | Texas | 78236 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute at University of Utah | Salt Lake City | Utah | 84112 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| St. Joseph Hospital Community Cancer Center | Bellingham | Washington | 98225 | — |
| Olympic Hematology and Oncology | Bremerton | Washington | 98310 | — |
| St. Francis Hospital | Federal Way | Washington | 98003 | — |
| Skagit Valley Hospital Cancer Care Center | Mount Vernon | Washington | 98273 | — |
| Capital Medical Center | Olympia | Washington | 98507 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98104 | — |
| Group Health Central Hospital | Seattle | Washington | 98104 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98114 | — |
| University Cancer Center at University of Washington Medical Center | Seattle | Washington | 98195 | — |
| North Puget Oncology at United General Hospital | Sedro-Woolley | Washington | 98284 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Allenmore Hospital | Tacoma | Washington | 98405 | — |
| CCOP - Northwest | Tacoma | Washington | 98405 | — |
| St. Clare Hospital | Tacoma | Washington | 98499 | — |
| Southwest Washington Medical Center Cancer Center | Vancouver | Washington | 98668 | — |
| Central Washington Hospital | Wenatchee | Washington | 98801 | — |
| Wenatchee Valley Clinic | Wenatchee | Washington | 98801 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00017147, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 30, 2013 · Synced Nov 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00017147 live on ClinicalTrials.gov.