Medical Therapy of Prostatic Symptoms
Public ClinicalTrials.gov record NCT00021814. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Medical Therapy of Prostatic Symptoms (MTOPS) is a clinical research study sponsored by the National Institutes of Health (NIH). The study will test whether the oral drugs finasteride (Proscar) and doxazosin (Cardura), alone or together, can delay or prevent further worsening of symptoms in men with Benign Prostatic Hyperplasia (BPH). MTOPS is the largest and longest study to simultaneously test whether these drugs can delay or prevent the clinical progression (symptom worsening) of BPH. Seventeen U.S. medical centers recruited 2,931 men diagnosed with symptomatic BPH between December 1995 and March 1998. Study doctors will continue to follow these men through November 2001 on a quarterly basis. In addition to the clinical progression of BPH, MTOPS will include evaluations of prostate volume by ultrasound, prostate biopsies among a subgroup of volunteers, and quality of life.
Study identification
- NCT ID
- NCT00021814
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,407 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- Male
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1995 (Actual)
- Primary completion
- Nov 30, 2001 (Actual)
- Completion
- Nov 30, 2001 (Actual)
- Last update posted
- Sep 28, 2018
1995 – 2001
United States locations
- U.S. sites
- 17
- U.S. states
- 14
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California | La Jolla | California | 92093-0694 | — |
| Univ of Colorado Health Sciences Center | Aurora | Colorado | 80010-0510 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Iowa Hospitals Clinics | Iowa City | Iowa | 52242 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Henry Ford Health Systems | Detroit | Michigan | 48202 | — |
| Mayo Foundation | Rochester | Minnesota | 55905 | — |
| Washington University | St Louis | Missouri | 63141 | — |
| New York University School of Medicine | New York | New York | 10010 | — |
| Columbia Presbyterian Medical Center | New York | New York | 10032 | — |
| Vanderbilt University | Nashville | Tennessee | 37232-2765 | — |
| UT Southwestern Medical Center | Dallas | Texas | 5235-9110 | — |
| Baylor College of Medicine | Houston | Texas | 77005 | — |
| Brooke Army Medical Center | San Antonio | Texas | 78234-6200 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00021814, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2018 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00021814 live on ClinicalTrials.gov.