ClinicalTrials.gov record
Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer
ClinicalTrials.gov ID: NCT00022087
Public ClinicalTrials.gov record NCT00022087. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Trial of Intravenous Zoledronic Acid (Zometa) in the Prevention of Bone Loss in Localized Breast Cancer Patients With Chemotherapy-Induced Ovarian Failure
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Zoledronate plus calcium and vitamin D may prevent bone loss in patients receiving adjuvant chemotherapy for breast cancer. It is not yet known which regimen is more effective in preventing bone loss. PURPOSE: This randomized phase III trial is comparing two regimens of zoledronate plus calcium and vitamin D to see how well they work in preventing bone loss in women who are receiving adjuvant chemotherapy for breast cancer.
Study identification
- NCT ID
- NCT00022087
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 439 participants
Conditions and interventions
Conditions
Interventions
- calcium salts Dietary Supplement
- cholecalciferol Dietary Supplement
- zoledronic acid Drug
Dietary Supplement · Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2001 (Type not available)
- Primary completion
- Mar 2007 (Actual)
- Completion
- Feb 2009 (Actual)
- Last update posted
- Jul 19, 2016
2001 – 2009
United States locations
- U.S. sites
- 107
- U.S. states
- 26
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arroyo Grande Community Hospital | Arroyo Grande | California | 93420 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Naval Medical Center - San Diego | San Diego | California | 92134 | — |
| Veterans Affairs Medical Center - San Diego | San Diego | California | 92161 | — |
| Kent General Hospital at Bayhealth Medical Center | Dover | Delaware | 19901 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| St. Francis Hospital | Wilmington | Delaware | 19805 | — |
| Lombardi Comprehensive Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Washington Cancer Institute at Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Michael & Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Memorial Cancer Institute at Memorial Regional Hospital | Hollywood | Florida | 33021 | — |
| Ella Milbank Foshay Cancer Center at Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Cancer Research Network, Incorporated | Plantation | Florida | 33324 | — |
| Cleveland Clinic Florida - Weston | Weston | Florida | 33331 | — |
| St. Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Graham Hospital | Canton | Illinois | 61520 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Eureka Community Hospital | Eureka | Illinois | 61530 | — |
| Galesburg Clinic | Galesburg | Illinois | 61401 | — |
| Galesburg Cottage Hospital | Galesburg | Illinois | 61401 | — |
| InterCommunity Cancer Center of Western Illinois | Galesburg | Illinois | 61401 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Hopedale Medical Complex | Hopedale | Illinois | 61747 | — |
| Kewanee Hospital | Kewanee | Illinois | 61443 | — |
| La Grange Memorial Hospital | La Grange | Illinois | 60525 | — |
| McDonough District Hospital | Macomb | Illinois | 61455 | — |
| BroMenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Community Cancer Center | Normal | Illinois | 61761 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453-2699 | — |
| Community Hospital of Ottawa | Ottawa | Illinois | 61350 | — |
| Cancer Treatment Center at Pekin Hospital | Pekin | Illinois | 61554 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61615 | — |
| Oncology/Hematology Associates of Central Illinois, P.C. | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| OSF St. Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois Valley Community Hospital | Peru | Illinois | 61354 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| St. Margaret's Hospital | Spring Valley | Illinois | 61362 | — |
| Valley Cancer Center | Spring Valley | Illinois | 61362 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Center for Cancer Therapy at LaPorte Hospital and Health Services | La Porte | Indiana | 46350 | — |
| Suniti Medical Corporation | Merrillville | Indiana | 46410 | — |
| CCOP - Northern Indiana CR Consortium | South Bend | Indiana | 46601 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Saint Joseph Regional Medical Center | South Bend | Indiana | 46617 | — |
| Hematology Oncology Associates of the Quad Cities | Bettendorf | Iowa | 52722 | — |
| Iowa Blood and Cancer Care | Cedar Rapids | Iowa | 52402 | — |
| St. Luke's Hospital | Cedar Rapids | Iowa | 52402 | — |
| Mercy Regional Cancer Center at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Central Maine Medical Center | Lewiston | Maine | 04240 | — |
| Maine Center for Cancer Medicine and Blood Disorders - Scarborough | Scarborough | Maine | 04074 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Harry and Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center | Baltimore | Maryland | 21237 | — |
| Union Hospital Cancer Center at Union Hospital | Elkton MD | Maryland | 21921 | — |
| Sturdy Memorial Hospital | Attleboro | Massachusetts | 02703 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Faulkner Hospital | Boston | Massachusetts | 02130 | — |
| Bethke Cancer Center at Emerson Hospital | Concord | Massachusetts | 01742 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Fairview University Medical Center - University Campus | Minneapolis | Minnesota | 55455 | — |
| Saint Luke's Hospital | Chesterfield | Missouri | 63017 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| Missouri Cancer Care, P. C. - Wentzville | Wentzville | Missouri | 63385 | — |
| Methodist Cancer Center at Methodist Hospital - Omaha | Omaha | Nebraska | 68114 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| CCOP - Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| New Hampshire Oncology-Hematology, PA - Hooksett | Hooksett | New Hampshire | 03106 | — |
| Lakes Region General Hospital | Laconia | New Hampshire | 03246 | — |
| Elliot Regional Cancer Center | Manchester | New Hampshire | 03103 | — |
| Oncology Center at St. Joseph Hospital | Nashua | New Hampshire | 03060 | — |
| Jersey City Medical Center at Liberty Health | Jersey City | New Jersey | 07302 | — |
| Cancer Institute of New Jersey at the Cooper University Hospital - Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Nalitt Cancer Institute at Staten Island University Hospital | Staten Island | New York | 10305 | — |
| CCOP - Hematology-Oncology Associates of Central New York | Syracuse | New York | 13057 | — |
| Community General Hospital of Greater Syracuse | Syracuse | New York | 13215 | — |
| Faxton Regional Cancer Center | Utica | New York | 13502 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Lenoir Memorial Cancer Center | Kinston | North Carolina | 28501 | — |
| Moore Regional Community Hospital Comprehensive Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224-1791 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Women and Infants Hospital of Rhode Island | Providence | Rhode Island | 02905 | — |
| Miriam Hospital at Lifespan | Providence | Rhode Island | 02906 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas | Texas | 75390 | — |
| Southwestern Vermont Regional Cancer Center | Bennington | Vermont | 05201 | — |
| Mountainview Medical | Berlin Corners | Vermont | 05602 | — |
| Fletcher Allen Health Care - University Health Center Campus | Burlington | Vermont | 05401 | — |
| Community Cancer Center at Rutland Regional Medical Center | Rutland | Vermont | 05701 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| St. Mary's Regional Cancer Center at St. Mary's Medical Center | Huntington | West Virginia | 25702 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00022087, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 19, 2016 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00022087 live on ClinicalTrials.gov.