TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine
Public ClinicalTrials.gov record NCT00023387. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Intensive Pharmacokinetic Study of Three Doses of Rifapentine (600, 900 and 1200mg) During Continuation Phase Therapy of Tuberculosis in HIV-Negative Adults
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary objective: To compare the pharmacokinetics of rifapentine and 25-desacetyl rifapentine at three different doses: 600 mg, 900 mg, and 1200 mg. Secondary objective: To describe any correlation between pharmacokinetic parameters of three different doses of rifapentine plus a standard dose of isoniazid and the occurrence of toxicity attributed to anti-tuberculosis treatment.
Study identification
- NCT ID
- NCT00023387
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 36 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2000 (Type not available)
- Primary completion
- Not listed
- Completion
- May 2001 (Type not available)
- Last update posted
- Sep 13, 2005
2000 – 2001
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Arkansas Veterans Health System | Little Rock | Arkansas | 72205 | — |
| LA County/USC Medical Center | Los Angeles | California | 90033 | — |
| University of California, San Francisco | San Francisco | California | 94110 | — |
| Denver Department of Public Health and Hospitals | Denver | Colorado | 80204 | — |
| Washington, D.C. VAMC | Washington D.C. | District of Columbia | 20422 | — |
| Chicago VA Medical Center (Lakeside) | Chicago | Illinois | 60611 | — |
| Hines VA Medical Center | Hines | Illinois | 60141 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21287-0003 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| New Jersey Medical School | Newark | New Jersey | 07107-3001 | — |
| New York University School of Medicine | New York | New York | 10016 | — |
| Columbia University/Presbyterian Medical Center | New York | New York | 10032 | — |
| Harlem Hospital Center | New York | New York | 10037 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center | Durham | North Carolina | 34222 | — |
| Nashville VA Medical Center | Nashville | Tennessee | 37212-2637 | — |
| University of North Texas Health Science Center | Fort Worth | Texas | 76107-2699 | — |
| Thomas Street Clinic | Houston | Texas | 77009 | — |
| Audi L. Murphy VA Hospital | San Antonio | Texas | 78284 | — |
| Seattle King County Health Department | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00023387, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 13, 2005 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00023387 live on ClinicalTrials.gov.