Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection
Public ClinicalTrials.gov record NCT00023452. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
TBTC Study 26: Effectiveness and Tolerability of Weekly Rifapentine/Isoniazid for 3 Months Versus Daily Isoniazid for 9 Months for the Treatment of Latent Tuberculosis Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Open-label, multi-center, Phase III clinical trial to compare the effectiveness and tolerability of a three-month (12-dose) regimen of weekly rifapentine and isoniazid (3RPT/INH) to the effectiveness of a nine-month (270-dose)regimen of daily isoniazid (9INH) to prevent tuberculosis (TB) among high-risk tuberculin skin-test reactors, including children and HIV-infected persons, who require treatment of latent TB infection (LTBI).
Study identification
- NCT ID
- NCT00023452
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,053 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2001 (Type not available)
- Primary completion
- Oct 2010 (Actual)
- Completion
- Sep 2013 (Actual)
- Last update posted
- Aug 27, 2024
2001 – 2013
United States locations
- U.S. sites
- 21
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Arkansas Veterans Health System | Little Rock | Arkansas | 72205 | — |
| LA County/USC Medical Center | Los Angeles | California | 90033 | — |
| UCSD Medical Center | San Diego | California | 92103 | — |
| University of California, San Francisco | San Francisco | California | 94110 | — |
| Denver Department of Public Health and Hospitals | Denver | Colorado | 80204 | — |
| Washington, D.C. VAMC | Washington D.C. | District of Columbia | 20422 | — |
| Emory University, Department of Medicine | Atlanta | Georgia | 30303 | — |
| Chicago VA Medical Center (Lakeside) | Chicago | Illinois | 60611 | — |
| Hines VA Medical Center | Hines | Illinois | 60141 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21287-0003 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| New Jersey Medical School | Newark | New Jersey | 07107-3001 | — |
| Columbia University/Presbyterian Medical Center | New York | New York | 10032 | — |
| Harlem Hospital Center | New York | New York | 10037 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center | Durham | North Carolina | 34222 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| University of North Texas Health Science Center | Fort Worth | Texas | 76107-2699 | — |
| Michael Debakey Veterans Affairs Medical Center | Houston | Texas | 77009 | — |
| Audi L. Murphy VA Hospital | San Antonio | Texas | 78284 | — |
| Seattle King County Health Department | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00023452, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 27, 2024 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00023452 live on ClinicalTrials.gov.