ClinicalTrials.gov record
Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer
ClinicalTrials.gov ID: NCT00023751
Public ClinicalTrials.gov record NCT00023751. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study of Local Excision Alone or Local Excision Plus Adjuvant Chemoradiation Therapy for Small Distal Rectal Cancers
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining surgery with chemotherapy and radiation therapy may kill more tumor cells and prevent recurrence of the cancer. PURPOSE: Phase II trial to study the effectiveness of surgery with or without chemotherapy and radiation therapy in treating patients who have stage I rectal cancer.
Study identification
- NCT ID
- NCT00023751
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 320 participants
Conditions and interventions
Conditions
Interventions
- fluorouracil Drug
- leucovorin calcium Drug
- conventional surgery Procedure
- radiation therapy Radiation
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2001
- Primary completion
- Mar 31, 2004
- Completion
- Mar 31, 2004
- Last update posted
- Jul 5, 2016
2001 – 2004
United States locations
- U.S. sites
- 178
- U.S. states
- 45
- U.S. cities
- 117
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Northeast Alabama Regional Medical Center | Anniston | Alabama | 36207 | — |
| MBCCOP - Gulf Coast | Mobile | Alabama | 36688 | — |
| CCOP - Greater Phoenix | Phoenix | Arizona | 85006-2726 | — |
| Veterans Affairs Medical Center - Phoenix (Carl T. Hayden) | Phoenix | Arizona | 85012 | — |
| Veterans Affairs Medical Center - Tucson | Tucson | Arizona | 85723 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Veterans Affairs Medical Center - Little Rock (McClellan) | Little Rock | Arkansas | 72205 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90033-0804 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Veterans Affairs Medical Center - West Los Angeles | Los Angeles | California | 90073 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Veterans Affairs Outpatient Clinic - Martinez | Martinez | California | 94553 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Veterans Affairs Medical Center - San Diego | San Diego | California | 92161 | — |
| Veterans Affairs Medical Center - San Francisco | San Francisco | California | 94121 | — |
| CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | 95403 | — |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80010 | — |
| Veterans Affairs Medical Center - Denver | Denver | Colorado | 80220 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Lombardi Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| MBCCOP - Howard University Cancer Center | Washington D.C. | District of Columbia | 20060 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Veterans Affairs Medical Center - Washington, DC | Washington D.C. | District of Columbia | 20422 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Memorial Regional Hospital Comprehensive Cancer Center | Hollywood | Florida | 33021 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Florida Hospital Cancer Institute | Orlando | Florida | 32804 | — |
| Helen and Harry Gray Cancer Institute at Good Samaritan Medical Center | West Palm Beach | Florida | 33401 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | — |
| Dwight David Eisenhower Army Medical Center | Fort Gordon | Georgia | 30905-5650 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813-2424 | — |
| MBCCOP - Hawaii | Honolulu | Hawaii | 96813 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| Robert H. Lurie Comprehensive Cancer Center, Northwestern University | Chicago | Illinois | 60611-W227 | — |
| MBCCOP - University of Illinois at Chicago | Chicago | Illinois | 60612-7323 | — |
| Veterans Affairs Medical Center - Chicago (Westside Hospital) | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Louis A. Weiss Memorial Hospital | Chicago | Illinois | 60640 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) | Hines | Illinois | 60141 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153-5500 | — |
| West Suburban Center for Cancer Care | River Forest | Illinois | 60305 | — |
| Saint Anthony Medical Center | Rockford | Illinois | 61108 | — |
| Fort Wayne Medical Oncology and Hematology, Incorporated | Fort Wayne | Indiana | 46885-5099 | — |
| CCOP - Northern Indiana CR Consortium | South Bend | Indiana | 46601 | — |
| Hematology Oncology Associates of the Quad Cities | Bettendorf | Iowa | 52722 | — |
| Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242-1009 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7353 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Veterans Affairs Medical Center - Wichita | Wichita | Kansas | 67218 | — |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40502-2236 | — |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | — |
| Baptist Hospital East - Louisville | Louisville | Kentucky | 40207 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Veterans Affairs Medical Center - New Orleans | New Orleans | Louisiana | 70112 | — |
| Louisiana State University Health Sciences Center - Shreveport | Shreveport | Louisiana | 71130-3932 | — |
| Veterans Affairs Medical Center - Shreveport | Shreveport | Louisiana | 71130 | — |
| Marlene and Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | — |
| Veterans Affairs Medical Center - Baltimore | Baltimore | Maryland | 21201 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Veterans Affairs Medical Center - Boston (Jamaica Plain) | Jamaica Plain | Massachusetts | 02130 | — |
| University of Massachusetts Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| Veterans Affairs Medical Center - Ann Arbor | Ann Arbor | Michigan | 48105 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0912 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Veterans Affairs Medical Center - Detroit | Detroit | Michigan | 48201-1932 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| CCOP - Grand Rapids | Grand Rapids | Michigan | 49503 | — |
| CCOP - Beaumont | Royal Oak | Michigan | 48073-6769 | — |
| Lakeland Medical Center - St. Joseph | Saint Joseph | Michigan | 49085 | — |
| Providence Hospital - Southfield | Southfield | Michigan | 48075-9975 | — |
| Veterans Affairs Medical Center - Minneapolis | Minneapolis | Minnesota | 55417 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Veterans Affairs Medical Center - Biloxi | Biloxi | Mississippi | 39531-2410 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Veterans Affairs Medical Center - Jackson | Jackson | Mississippi | 39216 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2576 | — |
| Veterans Affairs Medical Center - Columbia (Truman Memorial) | Columbia | Missouri | 65201 | — |
| Ellis Fischel Cancer Center - Columbia | Columbia | Missouri | 65203 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| CCOP - St. Louis-Cape Girardeau | St Louis | Missouri | 63141 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Veterans Affairs Medical Center - Las Vegas | Las Vegas | Nevada | 89106 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| Veterans Affairs Medical Center - Albuquerque | Albuquerque | New Mexico | 87108-5138 | — |
| MBCCOP - University of New Mexico HSC | Albuquerque | New Mexico | 87131 | — |
| Veterans Affairs Medical Center - Albany | Albany | New York | 12208 | — |
| Veterans Affairs Medical Center - Buffalo | Buffalo | New York | 14215 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Elmhurst Hospital Center | Elmhurst | New York | 11373 | — |
| Queens Cancer Center of Queens Hospital | Jamaica | New York | 11432 | — |
| CCOP - North Shore University Hospital | Manhasset | New York | 11030 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Weill Medical College of Cornell University | New York | New York | 10021 | — |
| Mount Sinai Medical Center, NY | New York | New York | 10029 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| James P. Wilmot Cancer Center | Rochester | New York | 14642 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Veterans Affairs Medical Center - Syracuse | Syracuse | New York | 13210 | — |
| CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | Syracuse | New York | 13217 | — |
| Veterans Affairs Medical Center - Asheville | Asheville | North Carolina | 28805 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| NorthEast Oncology Associates | Concord | North Carolina | 28025 | — |
| Veterans Affairs Medical Center - Durham | Durham | North Carolina | 27705 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Cape Fear Valley Health System | Fayetteville | North Carolina | 28302-2000 | — |
| Lenoir Memorial Hospital Cancer Center | Kinston | North Carolina | 28503-1678 | — |
| FirstHealth Moore Regional Hospital | Pinehurst | North Carolina | 28374 | — |
| New Hanover Regional Medical Center | Wilmington | North Carolina | 28402-9025 | — |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Veterans Affairs Medical Center - Fargo | Fargo | North Dakota | 58102 | — |
| Veterans Affairs Medical Center - Cincinnati | Cincinnati | Ohio | 45220-2288 | — |
| Barrett Cancer Center | Cincinnati | Ohio | 45267-0501 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195-9001 | — |
| CCOP - Columbus | Columbus | Ohio | 43206 | — |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| CCOP - Dayton | Dayton | Ohio | 45429 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Veterans Affairs Medical Center - Oklahoma City | Oklahoma City | Oklahoma | 73104 | — |
| Oregon Cancer Institute | Portland | Oregon | 97201-3098 | — |
| Veterans Affairs Medical Center - Portland | Portland | Oregon | 97207 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Lifespan: The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Veterans Affairs Medical Center - Charleston | Charleston | South Carolina | 29401-5799 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| University of Tennessee Cancer Institute | Memphis | Tennessee | 38103 | — |
| Danville Radiation Therapy Center | Memphis | Tennessee | 38104 | — |
| Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| Veterans Affairs Medical Center - Amarillo | Amarillo | Texas | 79106 | — |
| Veterans Affairs Medical Center - Dallas | Dallas | Texas | 75216 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234-6200 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0565 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4095 | — |
| Veterans Affairs Medical Center - Houston | Houston | Texas | 77030 | — |
| Texas Tech University Health Science Center | Lubbock | Texas | 79415 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229-3900 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78229 | — |
| Veterans Affairs Medical Center - Temple | Temple | Texas | 76504 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112-5550 | — |
| Veterans Affairs Medical Center - Salt Lake City | Salt Lake City | Utah | 84148 | — |
| Green Mountain Oncology Group | Bennington | Vermont | 05201 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Fletcher Allen Health Care - University Health Center Campus | Burlington | Vermont | 05401 | — |
| Veterans Affairs Medical Center - White River Junction | White River Junction | Vermont | 05009 | — |
| Martha Jefferson Hospital | Charlottesville | Virginia | 22901 | — |
| Virginia Oncology Associates - Norfolk | Norfolk | Virginia | 23502 | — |
| MBCCOP - Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc. | Roanoke | Virginia | 24014 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Veterans Affairs Medical Center - Seattle | Seattle | Washington | 98108 | — |
| CCOP - Northwest | Tacoma | Washington | 98405-0986 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| St. Mary's Medical Center | Huntington | West Virginia | 25701 | — |
| Ministry Medical Group - Northern Region | Rhinelander | Wisconsin | 54501 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00023751, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 5, 2016 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00023751 live on ClinicalTrials.gov.