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Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Acceptability of the Anti-Microbe Vaginal Gel, PMPA Gel

ClinicalTrials.gov ID: NCT00028132

Public ClinicalTrials.gov record NCT00028132. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 12:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I Safety and Acceptability Study of the Vaginal Microbicide Agent PMPA Gel

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the PMPA gel, which kills microbes, in HIV-infected and HIV-uninfected women. The majority of new HIV infections occur through heterosexual contact. A product that stops or slows the replication of HIV during sexual contact is needed. At present, there are no products that are completely effective. PMPA gel, also known as tenofovir, is an anti-microbe agent that may fight against sexual transmission of HIV and other sexually transmitted diseases (STDs). It is applied to the vagina and gives women the ability to control their disease-prevention activity.

Study identification

NCT ID
NCT00028132
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Enrollment
120 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Nov 30, 2005
Last update posted
Oct 31, 2021

Ends 2005

United States locations

U.S. sites
5
U.S. states
3
U.S. cities
4
Facility City State ZIP Site status
Harlem Prevention Ctr. CRS (El-Sadr CTU) New York New York 10037
Bronx- Lebanon Hospital Center Clinical Research Site (BLHC CRS) The Bronx New York 10457
3535 Market Street CRS Philadelphia Pennsylvania 19104
The Miriam Hosp., Div. of Infectious Disease Providence Rhode Island 02906
Women & Infants' Hosp. Providence Rhode Island 02906

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00028132, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 31, 2021 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00028132 live on ClinicalTrials.gov.

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