Brain Control of Blinking
Public ClinicalTrials.gov record NCT00030199. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cortical Control of Voluntary Blinking
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will use transcranial magnetic stimulation (TMS) to study how the brain controls movement of muscles in the face-in particular, those involved in eye blinking. TMS is a procedure that activates areas of the brain with magnetic pulses that travel through the scalp and the skull. Healthy normal volunteers 21 years of age and older may be eligible for this study. They must be free of any serious medical illness, have no neurological or psychiatric disorders or history of seizures, and must not be taking any medications that can affect nervous system function. Participants will undergo TMS and the electrical activity in muscles activated by the stimulation will be recorded. For TMS, an insulated wire coil is placed on the patient's scalp, and a brief electrical current is passed through the coil. This creates a magnetic pulse that travels through the scalp and skull and causes small electrical currents in the outer part of the brain. If the coil is placed over a nerve that controls muscles, there may be a twitch in the muscles, sometimes large enough to move the face. In other cases, there may be a feeling of movement or tingling sensation in the face. Stimulation over the muscles on the side of the head may cause some discomfort there or twitching of the jaw. During the stimulation, subjects may be asked to tense certain muscles slightly or perform other simple actions. Electrical activity of the muscles activated by the stimulation is recorded. This is done with both metal electrodes taped to the skin over the muscle and with fine needle electrodes inserted into the muscles around the eyes. The study usually takes less than 3 hours, with frequent breaks. If more time is required, the study will be broken into more than one session.
Study identification
- NCT ID
- NCT00030199
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 10 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2002
- Primary completion
- Not listed
- Completion
- Jan 31, 2004
- Last update posted
- Mar 3, 2008
2002 – 2004
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Institute of Neurological Disorders and Stroke (NINDS) | Bethesda | Maryland | 20892 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00030199, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 3, 2008 · Synced Sep 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00030199 live on ClinicalTrials.gov.