Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Public ClinicalTrials.gov record NCT00030628. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Trial Of The Role Of Whole Brain Radiation Therapy In Addition To Radiosurgery In The Management Of Patients With One To Three Cerebral Metastases
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Radiosurgery may be able to deliver x-rays directly to the tumor and cause less damage to normal tissue. It is not yet known if radiosurgery is more effective with or without whole-brain radiation therapy in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of radiosurgery with or without whole-brain radiation therapy in treating patients who have brain metastases.
Study identification
- NCT ID
- NCT00030628
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 480 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2001 (Type not available)
- Primary completion
- Mar 2005 (Actual)
- Completion
- Oct 2014 (Actual)
- Last update posted
- Jul 7, 2016
2001 – 2014
United States locations
- U.S. sites
- 37
- U.S. states
- 22
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294-3295 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85001-2071 | — |
| Foundation for Cancer Research and Education | Phoenix | Arizona | 85013 | — |
| Mount Diablo Regional Cancer Center | Concord | California | 94524-4110 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| UCSF Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| John Muir Comprehensive Cancer Center at John Muir Medical Center | Walnut Creek | California | 94598 | — |
| University of Colorado Cancer Center at University of Colorado Health Sciences Center | Aurora | Colorado | 80010 | — |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06520-8040 | — |
| Shands Cancer Center at the University of Florida Health Science Center | Gainesville | Florida | 32610-100277 | — |
| University of Illinois Medical Center | Chicago | Illinois | 60612 | — |
| Genesis Regional Cancer Center at Genesis Medical Center | Davenport | Iowa | 52803 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Josephine Ford Cancer Center at Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| John F. Kennedy Medical Center | Edison | New Jersey | 08818 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Carolina Neurosurgery and Spine Associates | Charlotte | North Carolina | 28232-2861 | — |
| American College of Surgeons Oncology Group | Durham | North Carolina | 27705 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212-4772 | — |
| University of Pittsburgh Medical Center - Shadyside Hospital | Pittsburgh | Pennsylvania | 15213-2582 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC St. Margaret | Pittsburgh | Pennsylvania | 15215 | — |
| Methodist Cancer Center at Methodist University Hospital | Memphis | Tennessee | 38104 | — |
| American Fork Hospital | American Fork | Utah | 84003 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| Massey Cancer Center at Virginia Commonwealth University | Richmond | Virginia | 23298-0631 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-7375 | — |
| Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00030628, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 7, 2016 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00030628 live on ClinicalTrials.gov.