Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate Cancer
Public ClinicalTrials.gov record NCT00030654. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Study of Patients With High Risk, Hormone-Naive Prostate Cancer: Androgen Blockade With 4 Cycles of Immediate Chemotherapy Versus Androgen Blockade With Delayed Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as luteinizing hormone-releasing hormone agonist, flutamide, and bicalutamide may stop the adrenal glands from producing androgens. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy may kill more tumor cells. It is not yet known whether chemotherapy given at the same time as hormone therapy is more effective than chemotherapy given after hormone therapy in treating prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of chemotherapy given at the same time as hormone therapy with that of chemotherapy given after hormone therapy in treating patients who have prostate cancer.
Study identification
- NCT ID
- NCT00030654
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 21 participants
Conditions and interventions
Conditions
Interventions
- bicalutamide Drug
- docetaxel Drug
- doxorubicin hydrochloride Drug
- estramustine phosphate sodium Drug
- flutamide Drug
- ketoconazole Drug
- paclitaxel Drug
- releasing hormone agonist therapy Drug
- vinblastine sulfate Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2002 (Type not available)
- Primary completion
- Feb 4, 2005 (Actual)
- Completion
- Feb 4, 2005 (Actual)
- Last update posted
- Oct 22, 2020
2002 – 2005
United States locations
- U.S. sites
- 75
- U.S. states
- 29
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Foundation for Cancer Research and Education | Phoenix | Arizona | 85013 | — |
| Veterans Affairs Medical Center - Tucson | Tucson | Arizona | 85723 | — |
| Veterans Affairs Medical Center - Little Rock | Little Rock | Arkansas | 72205 | — |
| Veterans Affairs Outpatient Clinic - Martinez | Martinez | California | 94553 | — |
| Medical Center of Aurora - South Campus | Aurora | Colorado | 80012-0000 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301-9019 | — |
| Memorial Hospital Cancer Center | Colorado Springs | Colorado | 80909 | — |
| Penrose Cancer Center at Penrose Hospital | Colorado Springs | Colorado | 80933 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| St. Joseph Hospital | Denver | Colorado | 80218-1191 | — |
| Presbyterian - St. Luke's Medical Center | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers - Denver Rose | Denver | Colorado | 80220 | — |
| CCOP - Colorado Cancer Research Program, Incorporated | Denver | Colorado | 80224 | — |
| Swedish Medical Center | Englewood | Colorado | 80112 | — |
| Sky Ridge Medical Center | Lone Tree | Colorado | 80124 | — |
| Hope Cancer Care Center at Longmont United Hospital | Longmont | Colorado | 80501 | — |
| St. Mary-Corwin Regional Medical Center | Pueblo | Colorado | 81004 | — |
| Rocky Mountain Cancer Centers - Thornton | Thornton | Colorado | 80221 | — |
| Shands Cancer Center at the University of Florida Health Science Center | Gainesville | Florida | 32610-0385 | — |
| University of Miami Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| Gulf Coast Cancer Treatment Center | Panama City | Florida | 32405-4587 | — |
| Tallahassee Memorial Hospital | Tallahassee | Florida | 32308 | — |
| Veterans Affairs Medical Center - Tampa (Haley) | Tampa | Florida | 33612 | — |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Veterans Affairs Medical Center - Hines | Hines | Illinois | 60141 | — |
| John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Mercy Cancer Center at Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| John Stoddard Cancer Center at Iowa Lutheran Hospital | Des Moines | Iowa | 50316-2301 | — |
| Wendt Regional Cancer Center at Finley Hospital | Dubuque | Iowa | 52001 | — |
| Veterans Affairs Medical Center - Wichita | Wichita | Kansas | 67218 | — |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40502-2236 | — |
| Veterans Affairs Medical Center - New Orleans | New Orleans | Louisiana | 70112 | — |
| Veterans Affairs Medical Center - Shreveport | Shreveport | Louisiana | 71101-4295 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0010 | — |
| Veterans Affairs Medical Center - Detroit | Detroit | Michigan | 48201-1932 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Veterans Affairs Medical Center - Jackson | Jackson | Mississippi | 39216 | — |
| Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| Midlands Cancer Center at Midlands Community Hospital | Papillion | Nebraska | 68128-4157 | — |
| Veterans Affairs Medical Center - Albuquerque | Albuquerque | New Mexico | 87108-5138 | — |
| MBCCOP - University of New Mexico HSC | Albuquerque | New Mexico | 87131 | — |
| NYU School of Medicine's Kaplan Comprehensive Cancer Center | New York | New York | 10016 | — |
| Lipson Cancer and Blood Center at Rochester General Hospital | Rochester | New York | 14621 | — |
| CCOP - Southeast Cancer Control Consortium | Goldsboro | North Carolina | 27534-9479 | — |
| Akron General's McDowell Cancer Center | Akron | Ohio | 44302 | — |
| Akron City Hospital at Summa Health System | Akron | Ohio | 44304 | — |
| Veterans Affairs Medical Center - Cincinnati | Cincinnati | Ohio | 45220-2288 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428-1002 | — |
| Cancer Care Center, Incorporated | Salem | Ohio | 44460 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Veterans Affairs Medical Center - Portland | Portland | Oregon | 97207 | — |
| Mercy Fitzgerald Hospital | Darby | Pennsylvania | 19023 | — |
| Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | 18501 | — |
| Veterans Affairs Medical Center - Charleston | Charleston | South Carolina | 29401-5799 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57709 | — |
| Erlanger Cancer Center | Chattanooga | Tennessee | 37403 | — |
| Veterans Affairs Medical Center - Memphis | Memphis | Tennessee | 38104 | — |
| Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center | Nashville | Tennessee | 37232-5671 | — |
| Veterans Affairs Medical Center - Amarillo | Amarillo | Texas | 79106 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0209 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78229 | — |
| Veterans Affairs Medical Center - Temple | Temple | Texas | 76504 | — |
| Cottonwood Hospital Medical Center | Murray | Utah | 84107 | — |
| McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84604 | — |
| Veterans Affairs Medical Center - Salt Lake City | Salt Lake City | Utah | 84148 | — |
| Dixie Regional Medical Center | St. George | Utah | 84770 | — |
| Veterans Affairs Medical Center - Seattle | Seattle | Washington | 98108 | — |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | 54301 | — |
| CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | 54449 | — |
| All Saints Cancer Center at All Saints Healthcare | Racine | Wisconsin | 53405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00030654, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2020 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00030654 live on ClinicalTrials.gov.