Safety and Efficacy of Natalizumab in Combination With Avonex in the Treatment of Multiple Sclerosis
Public ClinicalTrials.gov record NCT00030966. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Determine the Safety and Efficacy of Natalizumab, When Added to Avonex® (Interferon Beta-1a), in Subjects With Relapsing-Remitting Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if natalizumab in combination with AVONEX is safe and effective in delaying progression of individuals diagnosed with relapsing remitting Multiple Sclerosis (MS).
Study identification
- NCT ID
- NCT00030966
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2002 (Type not available)
- Primary completion
- Apr 2005 (Actual)
- Completion
- Dec 2005 (Actual)
- Last update posted
- Jun 18, 2009
2002 – 2005
United States locations
- U.S. sites
- 72
- U.S. states
- 32
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama-Birmingham, Department of Neurology | Birmingham | Alabama | 35233 | — |
| Phoenix Neurological Associates, Ltd. | Phoenix | Arizona | 85008 | — |
| University of Arkansas For Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California - Irvine | Irvine | California | 92697 | — |
| USC MS Comprehensive Care Center | Los Angeles | California | 90033 | — |
| Kaiser-Permanente Medical Center | Redwood City | California | 94063 | — |
| MS Center at UCSF | San Francisco | California | 94117 | — |
| Healthsouth Rehabilitation Hospital | Colorado Springs | Colorado | 80910 | — |
| University of Colorado MS Center | Denver | Colorado | 80262 | — |
| Griffin Hospital | Derby | Connecticut | 06418 | — |
| Georgetown Univesity Hospital, Research Pharmacy | Washington D.C. | District of Columbia | 20007 | — |
| George Washington University MS Center | Washington D.C. | District of Columbia | 20037 | — |
| North Ridge NeuroScience Center | Fort Lauderdale | Florida | 33334 | — |
| Maitland Neurology | Maitland | Florida | 32751 | — |
| University of Miami, Department of Neurology | Miami | Florida | 33136 | — |
| The Multiple Sclerosis Center of Atlanta | Atlanta | Georgia | 30327 | — |
| Marietta Neurological Associates | Marietta | Georgia | 30060 | — |
| Northwestern University, Department of Neurology | Chicago | Illinois | 60611 | — |
| Rush-Presbyterian St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Alexian Brothers Center for Clinical Research | Elk Grove Village | Illinois | 60007 | — |
| Loyola Medical Center | Maywood | Illinois | 60153 | — |
| Consultants in Neurology Northbrook | Northbrook | Illinois | 60062 | — |
| Springfield Clinic Neuroscience Institute | Springfield | Illinois | 62702 | — |
| Indiana University Medical Center | Indianapolis | Indiana | 46202 | — |
| Mercy Hospital Outpatient Pharmacy | Des Moines | Iowa | 50314 | — |
| LSU Neurolgoy Clinic in New Orleans | New Orleans | Louisiana | 70112 | — |
| Maine Neurology | Scarborough | Maine | 04074-8926 | — |
| University of Maryland Hospital, Department of Neurology | Baltimore | Maryland | 21201 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655-0138 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202-2608 | — |
| Michigan State University MS Clinic | East Lansing | Michigan | 48824 | — |
| Michigan Institute for Neurological Disorders | Farmington Hills | Michigan | 48334 | — |
| Noran Neurological Clinic | Minneapolis | Minnesota | 55404 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| St. John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| Bernard W. Gimbel MS Center | Teaneck | New Jersey | 07666 | — |
| Upstate Clinical Research, LLC | Albany | New York | 12205 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Maimonides Medical Center, Division of Neurology | Brooklyn | New York | 11219 | — |
| Buffalo General Hospital, Department of Neurology | Buffalo | New York | 14203 | — |
| MS Care Center | New York | New York | 10003 | — |
| St. Luke's Roosevelt Hospital, MS Research & Treatment Center | New York | New York | 10019 | — |
| New York Hospital - Cornell Medical Center | New York | New York | 10021 | — |
| New York State Psychiatric Institution | New York | New York | 10032 | — |
| Strong Health Pharmacy Services | Rochester | New York | 14642 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| University Hospital at Stony Brook | Stony Brook | New York | 11794 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| MS Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Raleigh Neurology Associates | Raleigh | North Carolina | 27607 | — |
| Wake Forest University School of Medicine, Department of Neurology | Winston-Salem | North Carolina | 27157 | — |
| Riverhills Neurology | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Greenstein Neurology Associates & MS Institute | Philadelphia | Pennsylvania | 19146 | — |
| Allegheny Singer Research Institute | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh, Department of Neurology | Pittsburgh | Pennsylvania | 15213 | — |
| University of Tennessee - Memphis | Memphis | Tennessee | 38163 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37215 | — |
| Option Care Infusion | Dallas | Texas | 75226 | — |
| UTSW Medical School | Dallas | Texas | 75235-9036 | — |
| Baylor Methodist International MS Center | Houston | Texas | 77030 | — |
| Central Texas Neurology | Round Rock | Texas | 78681 | — |
| Fletcher Allen Health Care | Burlington | Vermont | 05401 | — |
| University of Virginia Health Sciences | Charlottesville | Virginia | 22908 | — |
| Neurological Associates, Inc. | Richmond | Virginia | 23226 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98111 | — |
| MS Research Center | Seattle | Washington | 98195 | — |
| St. Francis Hospital, Center for Neurological Disorders | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00030966, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 18, 2009 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00030966 live on ClinicalTrials.gov.