ClinicalTrials.gov record
Hydroxychloroquine in Treating Patients With Newly Diagnosed Chronic Graft-Versus-Host Disease
ClinicalTrials.gov ID: NCT00031824
Public ClinicalTrials.gov record NCT00031824. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Trial of Hydroxychloroquine + Standard Therapy for Chronic Graft-Versus-Host Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Hydroxychloroquine may decrease the immune response and be effective in treating chronic graft-versus-host disease. It is not yet known if standard therapy for graft-versus-host disease is more effective with or without hydroxychloroquine. PURPOSE: Randomized phase III trial to compare the effectiveness of standard therapy alone with that of standard therapy plus hydroxychloroquine in treating patients who have newly diagnosed chronic graft-versus-host disease.
Study identification
- NCT ID
- NCT00031824
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 82 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 1 Year to 29 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2002 (Type not available)
- Primary completion
- May 2005 (Actual)
- Completion
- Jan 2011 (Actual)
- Last update posted
- Feb 14, 2014
2002 – 2011
United States locations
- U.S. sites
- 89
- U.S. states
- 35
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Cancer Center at University of Arizona Health Sciences Center | Tucson | Arizona | 85724 | — |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Southern California Permanente Medical Group | Downey | California | 90242 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010-3000 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027-0700 | — |
| University Medical Center at Princeton | Los Angeles | California | 90027-0700 | — |
| Kaiser Permanente Medical Center - Los Angeles | Los Angeles | California | 90027 | — |
| Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Jonsson Comprehensive Cancer Center at UCLA | Los Angeles | California | 90095-1781 | — |
| Children's Hospital and Research Center at Oakland | Oakland | California | 94609 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Lucile Packard Children's Hospital at Stanford University Medical Center | Palo Alto | California | 94304-1812 | — |
| Children's Hospital and Health Center, San Diego | San Diego | California | 92123-4282 | — |
| UCSF Comprehensive Cancer Center | San Francisco | California | 94143 | — |
| Presbyterian - St. Luke's Medical Center | Colorado Springs | Colorado | 80907 | — |
| Children's Hospital Cancer Center | Denver | Colorado | 80218 | — |
| Lombardi Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610-0296 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207-8482 | — |
| Miami Children's Hospital | Miami | Florida | 33155-4069 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus | Atlanta | Georgia | 30322 | — |
| MBCCOP-Medical College of Georgia Cancer Center | Augusta | Georgia | 30912-4000 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60601 | — |
| Children's Memorial Hospital - Chicago | Chicago | Illinois | 60614 | — |
| Riley Children Cancer Center at Riley Hospital for Children | Indianapolis | Indiana | 46202-5225 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536-0084 | — |
| Kosair Children's Hospital | Louisville | Kentucky | 40232 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Children's Hospital of New Orleans | New Orleans | Louisiana | 70118 | — |
| Maine Children's Cancer Program | Scarborough | Maine | 04074-9308 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21287 | — |
| Floating Hospital for Children | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114-2696 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0914 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Children's Hospitals and Clinics - Minneapolis/St. Paul | Minneapolis | Minnesota | 55404 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Methodist Cancer Center at Methodist Specialty and Transplant Hospital | St Louis | Missouri | 63104 | — |
| St. Louis Children's Hospital | St Louis | Missouri | 63110 | — |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | 68198-3330 | — |
| Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11042 | — |
| NYU Cancer Institute at New York University Medical Center | New York | New York | 10016 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | 10032 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | 27599-7070 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | — |
| Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University | Cleveland | Ohio | 44106-5065 | — |
| Columbus Children's Hospital | Columbus | Ohio | 43205-2696 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73190 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Cancer Institute at Oregon Health and Science University | Portland | Oregon | 97239-3098 | — |
| Doernbecher Children's Hospital at Oregon Health & Science University | Portland | Oregon | 97239-3098 | — |
| Children's Hospital at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Vanderbilt Children's Hospital | Nashville | Tennessee | 37232-6310 | — |
| Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas | Texas | 75390-9063 | — |
| Cook Children's Medical Center - Fort Worth | Fort Worth | Texas | 76104 | — |
| Baylor College of Medicine | Houston | Texas | 77030-2399 | — |
| M.D. Anderson Cancer Center at University of Texas | Houston | Texas | 77030-4009 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78207 | — |
| MBCCOP - South Texas Pediatrics | San Antonio | Texas | 78229-3900 | — |
| Pediatric Hematology and Oncology Associates of South Texas, PLLC | San Antonio | Texas | 78229 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute at University of Utah | Salt Lake City | Utah | 84112 | — |
| INOVA Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105 | — |
| Deaconess Medical Center | Spokane | Washington | 99210-0248 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-0001 | — |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | 54301 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-4108 | — |
| CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | 54449 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00031824, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 14, 2014 · Synced Nov 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00031824 live on ClinicalTrials.gov.