Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)
Public ClinicalTrials.gov record NCT00032487. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CSP #465 - Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a prospective, 2-arm, randomized controlled trial to determine whether glycemic control, achieved through intensification of treatment, is effective in preventing clinical macrovascular complications in patients with type 2 DM who are no longer responsive to oral agents alone. The study consists of a two-year accrual period and five years of follow-up (7 years total) of 1700 patients across 20 centers. We have powered the study to detect a 21% reduction in the primary event rate. Additional study goals are to determine whether the expenditures, discomfort, and adverse effects associated with intensive intervention are justified in terms of their clinical benefits, considering both macrovascular and microvascular complications.
Study identification
- NCT ID
- NCT00032487
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,791 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2000
- Primary completion
- May 29, 2008
- Completion
- May 29, 2008
- Last update posted
- Mar 29, 2017
2000 – 2008
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Carl T. Hayden VA Medical Center | Phoenix | Arizona | 85012 | — |
| Southern Arizona VA Health Care System, Tucson | Tucson | Arizona | 85723 | — |
| VA Central California Health Care System, Fresno | Fresno | California | 93703 | — |
| VA Medical Center, Long Beach | Long Beach | California | 90822 | — |
| VA San Diego Healthcare System, San Diego | San Diego | California | 92161 | — |
| Miami VA Healthcare System, Miami, FL | Miami | Florida | 33125 | — |
| Edward Hines, Jr. VA Hospital | Hines | Illinois | 60141-5000 | — |
| Richard Roudebush VA Medical Center, Indianapolis | Indianapolis | Indiana | 46202-2884 | — |
| VA Medical Center, Lexington | Lexington | Kentucky | 40502 | — |
| VA Medical Center, Minneapolis | Minneapolis | Minnesota | 55417 | — |
| VA Medical Center, Omaha | Omaha | Nebraska | 68105-1873 | — |
| VA New Jersey Health Care System, East Orange | East Orange | New Jersey | 07018 | — |
| VA Pittsburgh Health Care System | Pittsburgh | Pennsylvania | 15240 | — |
| Ralph H Johnson VA Medical Center, Charleston | Charleston | South Carolina | 29401-5799 | — |
| VA Medical Center | Nashville | Tennessee | 37212-2637 | — |
| Michael E. DeBakey VA Medical Center (152) | Houston | Texas | 77030 | — |
| VA South Texas Health Care System, San Antonio | San Antonio | Texas | 78229 | — |
| Hunter Holmes McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| VA Medical Center, Salem VA | Salem | Virginia | 24153 | — |
| VA Puget Sound Health Care System, Seattle | Seattle | Washington | 98108 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00032487, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 29, 2017 · Synced Sep 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00032487 live on ClinicalTrials.gov.