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Completed Phase 3 Interventional

Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)

ClinicalTrials.gov ID: NCT00032890

Public ClinicalTrials.gov record NCT00032890. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 23, 2026, 11:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will determine whether glucosamine, chondroitin sulfate and/or the combination of glucosamine and chondroitin sulfate are more effective than placebo and whether the combination is more effective than glucosamine or chondroitin sulfate alone in the treatment of knee pain associated with osteoarthritis (OA) of the knee after six months of follow-up. These substances, marketed in the United States as dietary supplements, have been widely touted by the lay press and by anecdotal personal experience as effective in treating OA. To date, however, only a few small studies have been published in the worldwide literature. The study proposed herein has been carefully constructed to definitively determine the efficacy of these agents.

Study identification

NCT ID
NCT00032890
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
1,588 participants

Conditions and interventions

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2000
Primary completion
Not listed
Completion
Jan 31, 2004
Last update posted
Jan 20, 2009

2000 – 2004

United States locations

U.S. sites
16
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294-7201
*University of Arizona Arthritis Center Tucson Arizona 85724
*Cedars-Sinai Medical Center Los Angeles California 90048
*University of California, Los Angeles Los Angeles California 90095
*University of California San Francisco San Francisco California 94110
Northwestern University Chicago Illinois 60611
*Indiana University School of Medicine Indianapolis Indiana 46202-5103
*Arthritis Research and Clinical Centers Wichita Kansas 67214
University of Nebraska Medical Center Omaha Nebraska 68198-3025
Hospital for Joint Diseases New York New York 10003
*Case Western Reserve University Beachwood Ohio 44122
University of Pennsylvania Philadelphia Pennsylvania 19104
*University of Pittsburgh Pittsburgh Pennsylvania 15213
Arthritis Consultation Center Dallas Texas 75231-4496
*University of Utah Salt Lake City Utah 84132
Virginia Mason Research Center Seattle Washington 98101

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00032890, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 20, 2009 · Synced Sep 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00032890 live on ClinicalTrials.gov.

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