Safety and Efficacy of OP2000 (Deligoparin) in the Treatment of Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT00033943. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Placebo-Controlled Evaluation of the Safety and Efficacy of Two Dosage Levels of OP2000 (75 Mg and 125 Mg) Administered Once Daily by Subcutaneous Injection for the Treatment of Active Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the effectiveness and safety of the experimental compound OP2000 (deligoparin) in patients with active ulcerative colitis. Patients eligible for this study will have received (and will continue to receive) stable doses of aminosalicylates (oral, enema and/or suppository), if tolerated. OP2000 is an ultra low molecular weight heparin with anticoagulant (blood thinning) and anti-inflammatory actions that may be of benefit for the treatment of ulcerative colitis.
Study identification
- NCT ID
- NCT00033943
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 270 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 60 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2001 (Type not available)
- Primary completion
- Not listed
- Completion
- Sep 2002 (Type not available)
- Last update posted
- Jun 24, 2005
2001 – 2002
United States locations
- U.S. sites
- 33
- U.S. states
- 20
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AGMG Clinical Research | Anaheim | California | 92801 | — |
| Community Clinical Trials | Orange | California | 92868 | — |
| Rocky Mountain Gastroenterology Associates | Lakewood | Colorado | 80215 | — |
| Rocky Mountain Clinical Research | Littleton | Colorado | 80120 | — |
| University of Florida Gainesville/Gainesville VAMC | Gainesville | Florida | 32608 | — |
| Borland-Groover Clinic | Jacksonville | Florida | 32223 | — |
| University of Miami, Division of Clinical Pharmacology | Miami | Florida | 33136 | — |
| Miami Research Associates | Miami | Florida | 33173 | — |
| Atlanta Gastroenterology Associates, LLC | Atlanta | Georgia | 30342 | — |
| Univ. of Kentucky Medical Center | Lexington | Kentucky | 40536 | — |
| Metropolitan Gastroenterology Group | Chevy Chase | Maryland | 20815 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | — |
| Minnesota Clinical Research Center | Saint Paul | Minnesota | 55114 | — |
| Washington Univ. School of Medicine | St Louis | Missouri | 63110 | — |
| Gastroenterology Specialties, PC | Lincoln | Nebraska | 68503 | — |
| Long Island Clinical Research Associates | Great Neck | New York | 11021 | — |
| Daniel H. Present, MD | New York | New York | 10028 | — |
| Univ. of North Carolina Hospital | Chapel Hill | North Carolina | 27599 | — |
| Charlotte Gastroenterology & Hepatology, PLLC | Charlotte | North Carolina | 28207 | — |
| Duke Health Center | Durham | North Carolina | 27710 | — |
| Wake Research Associates, LLC | Raleigh | North Carolina | 27612 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Oklahoma Foundation for Digestive Research | Oklahoma City | Oklahoma | 73104 | — |
| Gastroenterology United of Tulsa | Tulsa | Oklahoma | 74135 | — |
| West Hills Gastroenterology | Portland | Oregon | 97225 | — |
| Hospital of the Univ. of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Memphis Gastroenterology Group, PC | Memphis | Tennessee | 38120 | — |
| Nashville Clinical Research | Nashville | Tennessee | 37211 | — |
| GANT Research, PA | Fort Worth | Texas | 76102 | — |
| Gastroenterology Clinic of San Antonio | San Antonio | Texas | 78229 | — |
| Univ. of Virginia Health System | Charlottesville | Virginia | 22908 | — |
| Wisconsin Center for Advanced Research, LLC | Milwaukee | Wisconsin | 53207 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00033943, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00033943 live on ClinicalTrials.gov.