Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation.
Public ClinicalTrials.gov record NCT00035464. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Atrial fibrillation (an abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (a type of abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes of atrial fibrillation. Azimilide may have an effect on increasing the time to first recurrence of symptomatic atrial fibrillation or atrial flutter and symptomatic paroxysmal supraventricular tachycardia (other types of abnormal heart rhythms). This double-blind, placebo-controlled study is designed to evaluate the efficacy and safety of azimilide compared with placebo in prolonging the time to the first symptomatic arrhythmia recurrence in patients with a history of atrial fibrillation and congestive heart failure and/or ischemic heart disease) and those without these conditions. Once this phase of the study is completed, a second phase with a different study design will be conducted. The second phase is an open-label, follow-up phase. The follow-up phase of the study is designed to evaluate the long-term efficacy and safety of a daily oral dose of azimilide in patients who complete the double-blind, placebo-controlled phase of this study.
Study identification
- NCT ID
- NCT00035464
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 431 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2000 (Type not available)
- Primary completion
- Jan 2004 (Actual)
- Completion
- Jan 2004 (Actual)
- Last update posted
- Oct 3, 2011
2000 – 2004
United States locations
- U.S. sites
- 88
- U.S. states
- 34
- U.S. cities
- 82
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiovascular Assoc. PC | Birmingham | Alabama | 35213 | — |
| The Heart Group, PC | Mobile | Alabama | 36608 | — |
| Southern Arizona VA Health Care System, Section of Cardiology (1-111C) | Tucson | Arizona | 85723 | — |
| University Medical Center | Tucson | Arizona | 85742 | — |
| University of Arkansas Medical Center | Little Rock | Arkansas | 72205 | — |
| Cardiovascular Associates of Penisula | Burlingame | California | 94010 | — |
| Capitol Interventional Cardiology | Carmichael | California | 95608 | — |
| VA Central California Health Care System | Fresno | California | 93703 | — |
| Valley Research | Fresno | California | 93720 | — |
| Grass Valley Cardiology | Grass Valley | California | 95945 | — |
| San Diego Cardiovascular Associates | La Jolla | California | 92037 | — |
| Good Samaritan Hospital | Los Angeles | California | 90017 | — |
| LAC+USC Medical Center | Los Angeles | California | 90033 | — |
| Cardiology Section, West Los Angeles VA Hospital | Los Angeles | California | 90073 | — |
| Merced Heart Associates | Merced | California | 95340 | — |
| Sutter Gould Medical Foundation | Modesto | California | 95355 | — |
| ARI Clinical Trials | Redondo Beach | California | 90277 | — |
| Regional Cardiology Assoc. | Sacramento | California | 95819 | — |
| Sacramento Heart and Vascular Medical Associates | Sacramento | California | 95825 | — |
| Cardiology Associates | San Diego | California | 92120 | — |
| Aurora Denver Cardiology | Aurora | Colorado | 80012 | — |
| Western Cardiology Assoc. | Denver | Colorado | 80218 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| The George Washington University MFA | Washington D.C. | District of Columbia | 20037 | — |
| Cardiology Consultants | Daytona Beach | Florida | 32114 | — |
| C/O Research Office Attn: Cardiovascular Research Dept. | Fort Lauderdale | Florida | 33316 | — |
| SW Florida Heart Group/Health Park Medical Center | Fort Myers | Florida | 33919 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Watson Clinic, LLP | Lakeland | Florida | 33805 | — |
| Khalid Hassan Sheikh 80 Fontenberry Road | Merritt Island | Florida | 32952 | — |
| Florida Cardiology | Orlando | Florida | 32803 | — |
| Cardiology Research Assiocates | Ormond Beach | Florida | 32174 | — |
| VA Medical Center | Decatur | Georgia | 30033 | — |
| Mount Sinal Hospital Medical Center | Chicago | Illinois | 60608 | — |
| Elgin Cardiology Associates | Elgin | Illinois | 60120 | — |
| Illinois Heart & Lung Research Center, SC | Normal | Illinois | 61761-3587 | — |
| The Center for Advanced Cardiology | Park Ridge | Illinois | 60068 | — |
| Heart Center Medical Group | Fort Wayne | Indiana | 46804 | — |
| The Care Group | Indianapolis | Indiana | 46260-1919 | — |
| Professional Research Network of Kansas | Wichita | Kansas | 67203 | — |
| University of Louisville-Cardiology | Louisville | Kentucky | 40202 | — |
| Louisville Cardiology Medical Group, P.S.C | Louisville | Kentucky | 40207 | — |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| Richard Gilmore, MD 501 S Ryan Street | Lake Charles | Louisiana | 70601 | — |
| Cardiovascular of the South | Morgan City | Louisiana | 70380 | — |
| Cardiovascular Institute of the South | New Iberia | Louisiana | 70560 | — |
| Tulane University | New Orleans | Louisiana | 70112 | — |
| Medical Research Institute | Slidell | Louisiana | 70458 | — |
| Cardiovascular Institute of the South | Thibodaux | Louisiana | 70301 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| University of Massachusett | Worcester | Massachusetts | 01655 | — |
| Thoracic & Cardiovascular Healthcare Foundation | Lansing | Michigan | 48910 | — |
| Nisus Research | Petoskey | Michigan | 49770 | — |
| Riverside Osteopathic Hospital | Trenton | Michigan | 48183 | — |
| Regional Heart Center | Duluth | Minnesota | 55802 | — |
| Fairview Range Regional Health Services | Hibbing | Minnesota | 55746 | — |
| VA Medical Center Therapeutic Section | Minneapolis | Minnesota | 55417 | — |
| St. Patrick Hosp/Western Mt. Clinic Cardiology | Missoula | Montana | 59802 | — |
| Internal Medical Associates | Grand Island | Nebraska | 68803 | — |
| William Olney, MD 21 Whitehall Rd, Suite 200 | Rochester | New Hampshire | 03867 | — |
| Cardiology & Int. Medicine | Williamsville | New York | 14221 | — |
| Duke Medical Center | Durham | North Carolina | 27710 | — |
| Altru Health System Research Center | Grand Forks | North Dakota | 58201 | — |
| Lindner Clinical Trial Ctr. | Cincinnati | Ohio | 45219 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106-5038 | — |
| MidWest Cardiology Research Foundation | Columbus | Ohio | 43214 | — |
| Oklahoma Foundation for Cardiovascular Research | Oklahoma City | Oklahoma | 73104 | — |
| Hillsboro Cardiology | Hillsboro | Oregon | 97123 | — |
| Oregon Health Sciences University | Portland | Oregon | 97201 | — |
| Heart Care Group PC | Allentown | Pennsylvania | 18106-0880 | — |
| Tri-State Medical Group Cardiology | Beaver | Pennsylvania | 15009 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| The Pavillion | Jenkintown | Pennsylvania | 19046 | — |
| UPHS/Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Cardiovascular and Critical Care Associates, P.C. | Pittsburgh | Pennsylvania | 15224 | — |
| Charleston Cardiology | Charleston | South Carolina | 29403 | — |
| Stern Cardiovascular Center Research Department | Memphis | Tennessee | 38120 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390-9047 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Heart and Vascular Inst. of Texas, PA | San Antonio | Texas | 78217 | — |
| MedSource, Inc | Chesapeake | Virginia | 23321 | — |
| Riverside Regional Medical Center | Newport News | Virginia | 23601 | — |
| Daniel Gottlieb, MD 16259 Sylvester Road SW, Suite 401 | Seattle | Washington | 95165 | — |
| Beloit Clinic, SC | Beloit | Wisconsin | 53511 | — |
| Dean/Riverview Clinic | Janesville | Wisconsin | 53547-0551 | — |
| University of Wisconsin Madison | Madison | Wisconsin | 53792 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00035464, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 3, 2011 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00035464 live on ClinicalTrials.gov.