Efficacy and Safety of Azimilide for the Treatment of Patients With Atrial Fibrillation
Public ClinicalTrials.gov record NCT00035477. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Atrial fibrillation (abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes of atrial fibrillation. Azimilide may have an effect on increasing the time to first recurrence of symptomatic atrial fibrillation or atrial flutter and symptomatic paroxysmal supraventricular tachycardia (other types of abnormal heart rhythms). This double-blind, placebo-controlled study is designed to evaluate the efficacy and safety of azimilide compared with placebo in maintaining sinus rhythm in patients who require cardioversion (electric shock to correct heart rhythm) to reduce atrial fibrillation. Once this phase of the study is completed, a second phase with a different study design will be conducted. The second phase is an open-label follow-up phase to the study. This follow-up phase will continue to evaluate the long-term efficacy and safety of a daily oral dose of azimilide in patients who complete the double-blind, placebo-controlled phase of this study.
Study identification
- NCT ID
- NCT00035477
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 446 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2000 (Type not available)
- Primary completion
- Oct 2003 (Actual)
- Completion
- Oct 2003 (Actual)
- Last update posted
- Oct 3, 2011
2000 – 2003
United States locations
- U.S. sites
- 69
- U.S. states
- 27
- U.S. cities
- 66
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Heart Group, PC | Mobile | Alabama | 36608 | — |
| University Medical Center | Tucson | Arizona | 85742 | — |
| Cardiovascular Associates of Penisula | Burlingame | California | 94010 | — |
| San Diego Cardiovascular Research Associates | Encinitas | California | 92024 | — |
| La Mesa Cardiac Center, a Medical Group | La Mesa | California | 91942 | — |
| Good Samaritan Hospital | Los Angeles | California | 90017 | — |
| LAC + USC Medical Center | Los Angeles | California | 90033 | — |
| Cardiology Section, West Los Angeles VA Hospital | Los Angeles | California | 90073 | — |
| Merced Heart Associates | Merced | California | 95340 | — |
| Sutter Gould Medical Foundation | Modesto | California | 95335 | — |
| ARI Clinical Trials | Redondo Beach | California | 90277 | — |
| Inland Clinical Research | Riverside | California | 92501 | — |
| Regional Cardiology Assoc. | Sacramento | California | 95819 | — |
| Cardiology Associates | San Diego | California | 92120 | — |
| Western Cardiology Assoc. | Denver | Colorado | 80218 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| The George Washington University MFA | Washington D.C. | District of Columbia | 20037 | — |
| Cardiology Consultants | Daytona Beach | Florida | 32114 | — |
| C/O Research Office Attn: Cardiovascular Research Dept. | Fort Lauderdale | Florida | 33316 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Lakeland Regional Medical | Lakeland | Florida | 33805 | — |
| Khalid Hasan Sheikh 80 Fortenberry Road | Merritt Island | Florida | 32952 | — |
| Florida Cardiology | Orlando | Florida | 32803 | — |
| Cardiology Reasearch Assiocates | Ormond Beach | Florida | 32174 | — |
| VA Medical Center | Decatur | Georgia | 30033 | — |
| Elgin Cardiology Associates | Elgin | Illinois | 60120 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| Heart Center Medical Group | Fort Wayne | Indiana | 46804 | — |
| The Care Group | Indianapolis | Indiana | 46260 | — |
| University of Louisville-Cardiology | Louisville | Kentucky | 40202 | — |
| Louisville Cardiology Medical Group, P.S.C. | Louisville | Kentucky | 40207 | — |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| Richard Gilmore 501 S. Ryan Street | Lake Charles | Louisiana | 70601 | — |
| Cardiovascular Instiute of the South | Morgan City | Louisiana | 70380 | — |
| Tulane University | New Orleans | Louisiana | 70112 | — |
| Androscoggin Cardiology Associates Research | Auburn | Maine | 04201 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| University of Massachusett | Worcester | Massachusetts | 01655 | — |
| Thoracic & Cardiovascular Healthcare Foundation | Lansing | Michigan | 48910 | — |
| Riverside Osteopathic Hospital | Trenton | Michigan | 48183 | — |
| Regional Heart Center | Duluth | Minnesota | 55805 | — |
| VA Medical Center Therapeutic Section | Minneapolis | Minnesota | 55417 | — |
| St. Paul Heart Clinic | Saint Paul | Minnesota | 55102 | — |
| Duke Medical Center | Durham | North Carolina | 27710 | — |
| Altru Health System Research Center | Grand Forks | North Dakota | 58201 | — |
| Lindner Clinical Trial Ctr. | Cincinnati | Ohio | 45219 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Hillsboro Cardiology | Hillsboro | Oregon | 97123 | — |
| Oregon Health Sciences University | Portland | Oregon | 97201 | — |
| Heart Care Group PC | Allentown | Pennsylvania | 18106 | — |
| Tri-State Medical Group Cardiology | Beaver | Pennsylvania | 15009 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| The Pavillion | Jenkintown | Pennsylvania | 19046 | — |
| UPHS/Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Cardiovascular and Critical Care Associates, P.C. | Pittsburgh | Pennsylvania | 15224 | — |
| Cardiology Foundation of Lankenau | Wynnewood | Pennsylvania | 19096 | — |
| Charleston Cardiology | Charleston | South Carolina | 29403 | — |
| Stern Cardiovascular Center Research Department | Memphis | Tennessee | 38120 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Heart and Vascular Inst. of Texas, PA | San Antonio | Texas | 78217 | — |
| Riverside Regional Medical Center | Newport News | Virginia | 23601 | — |
| Daniel Gottlieb 16259 Sylvester Road SW Suite 401 | Seattle | Washington | 98166 | — |
| FHS Research | Tacoma | Washington | 98405 | — |
| Beloit Clinic, SC | Beloit | Wisconsin | 53511 | — |
| Wisconsin Center for Clinical Research | Elkhorn | Wisconsin | 53121 | — |
| Dean/Riverview Clinic | Janesville | Wisconsin | 53547 | — |
| University of Wisconsin Madison | Madison | Wisconsin | 53792 | — |
| Wisconsin Center for Clinical Research | Milwaukee | Wisconsin | 53251 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00035477, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 3, 2011 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00035477 live on ClinicalTrials.gov.