Study to Assess Efficacy of Tacrolimus + Methotrexate Versus Placebo + Methotrexate in Treatment of Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT00036153. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind Study to Assess the Efficacy of Tacrolimus (Prograf®)+ Methotrexate Vs. Placebo + Methotrexate in the Treatment of Rheumatoid Arthritis in Patients With Partial Response to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy of the combination of tacrolimus + methotrexate compared to methotrexate alone in the treatment of the signs and symptoms of rheumatoid arthritis over 6 months in patients with partial response to methotrexate.
Study identification
- NCT ID
- NCT00036153
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 210 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2002
- Primary completion
- Not listed
- Completion
- Dec 31, 2003
- Last update posted
- Mar 26, 2012
2002 – 2004
United States locations
- U.S. sites
- 42
- U.S. states
- 19
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| Rheumatology Associates of North Alabama | Huntsville | Alabama | 35801 | — |
| Radiant Research, Pharmaceutical Clinical Trials Division | Scottsdale | Arizona | 85251 | — |
| Boling Clinical Trials | Rancho Cucamonga | California | 91730 | — |
| San Diego Arthritis & Osteoporosis Medical Clinic | San Diego | California | 92120 | — |
| Pacific Arthritis Center and Medical Group | Santa Maria | California | 93454 | — |
| Arthritis Associates of CT | Danbury | Connecticut | 06810 | — |
| Stamford Therapeutic Consortium | Stamford | Connecticut | 06905 | — |
| Center of Rheumatology, Immunology & Arthritis | Fort Lauderdale | Florida | 33334 | — |
| Arthritis Center | Palm Harbor | Florida | 34684 | — |
| Sarasota Arthritis Center, Rheumatology Division | Sarasota | Florida | 34239 | — |
| Arthritis & Rheumatology Associates of Palm Beach | West Palm Beach | Florida | 33401 | — |
| Coeur d'Alene Arthritis Clinic | Coeur d'Alene | Idaho | 83814 | — |
| Northwestern Center for Clinical Research | Chicago | Illinois | 60611 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Illinois Bone & Joint Institute | Morton Grove | Illinois | 60053 | — |
| Rockford Clinical | Rockford | Illinois | 61103 | — |
| The Arthritis Center | Springfield | Illinois | 62704 | — |
| Arthritis & Osteoporosis Center of Maryland | Frederick | Maryland | 21702 | — |
| Phase III Clinical Research | Fall River | Massachusetts | 02720 | — |
| Midwest Arthritis Center | Kalamazoo | Michigan | 49048 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| St. Louis Center for Clinical Research | St Louis | Missouri | 63128 | — |
| Arthritis Consultants | St Louis | Missouri | 63141 | — |
| Arthritis Regional Research Center | Mercerville | New Jersey | 08619 | — |
| New Jersey Physicians, LLC | Passaic | New Jersey | 07055 | — |
| North Carolina Arthritis & Allergy Care Center | Raleigh | North Carolina | 27609 | — |
| Radiant Research - Columbus | Columbus | Ohio | 43212 | — |
| STAT Research, Inc. | Dayton | Ohio | 45402 | — |
| PRO Research | Eugene | Oregon | 97401 | — |
| Oregon Health Sciences Center | Portland | Oregon | 97201 | — |
| Portland Medical Associates, P.C. | Portland | Oregon | 97224 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Center for Assessment & Research of Erie | Erie | Pennsylvania | 16508 | — |
| Central Pennsylvania Clinical Research | Mechanicsburg | Pennsylvania | 17055 | — |
| Clinical Research Center of Reading, LLP | West Reading | Pennsylvania | 19611 | — |
| Rheumatic Disease Associates | Willow Grove | Pennsylvania | 19090 | — |
| Radiant Research - Dallas | Dallas | Texas | 75235 | — |
| San Antonio Center for Clinical Research | San Antonio | Texas | 78229 | — |
| Physicians Research Options, L.C. | Sandy City | Utah | 84070 | — |
| Metropolitan Clinical Research | Falls Church | Virginia | 22044 | — |
| Lewis-Gale Clinic | Salem | Virginia | 24153 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00036153, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2012 · Synced Sep 13, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00036153 live on ClinicalTrials.gov.