ClinicalTrials.gov record
Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures
ClinicalTrials.gov ID: NCT00041925
Public ClinicalTrials.gov record NCT00041925. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multi-Center Randomized, Double-Blind, Placebo-Controlled Trial of the Ex Vivo Treatment With CGT003 of Peripheral Vein Grafts in Patients Undergoing Peripheral Arterial Bypass Graft Procedures
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy of graft pretreatment with the E2F decoy, CGT003, as compared to placebo, on the occurrence of graft failure among patients who receive autogenous vein grafts to treat chronic critical limb ischemia; on the occurrence of clinically significant graft stenosis (more than or equal to 70%); and on the incidence of critical limb ischemia (e.g., gangrene, non-healing ischemic ulcers or ischemic rest pain).
Study identification
- NCT ID
- NCT00041925
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 1,400 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2001 (Type not available)
- Primary completion
- Not listed
- Completion
- Nov 2004 (Type not available)
- Last update posted
- Jul 15, 2005
2001 – 2004
United States locations
- U.S. sites
- 116
- U.S. states
- 34
- U.S. cities
- 64
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Kirklin Clinic | Birmingham | Alabama | 35233 | — |
| University Hospital | Birmingham | Alabama | 35294 | — |
| Mobile Infirmary Medical Center | Mobile | Alabama | 36607 | — |
| Vascular Specialists of Mobile, PC | Mobile | Alabama | 36607 | — |
| Springhill Memorial Hopsital | Mobile | Alabama | 36608 | — |
| Tucson Heart Hospital | Tucson | Arizona | 85704 | — |
| University Medical Center | Tucson | Arizona | 85724 | — |
| Northwest Hospital | Tucson | Arizona | 85741 | — |
| Tucson Vascular Surgery | Tucson | Arizona | 85741 | — |
| Southern Arizona Vascular Institute | Tucson | Arizona | 85745 | — |
| St. Mary's Hospital | Tucson | Arizona | 85745 | — |
| Baptist Health | Little Rock | Arkansas | 72205 | — |
| Central Arkansas Veterans Healthcare System | Little Rock | Arkansas | 72205 | — |
| University of Arkansas for Medical Sciences Hospital | Little Rock | Arkansas | 72205 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | — |
| Kaiser Permanente - San Diego, SCPMG, Department of Surgery | San Diego | California | 92120 | — |
| Kaiser Permanente Franklin Medical Center | Denver | Colorado | 80205 | — |
| Exempla Healthcare Saint Joseph Hospital | Denver | Colorado | 80218 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Washington Hospital Center, Center for Vascular Care | Washington D.C. | District of Columbia | 20010 | — |
| Malcom Randall VA Medical Center | Gainesville | Florida | 32608 | — |
| Shands Hospital at the University of Florida | Gainesville | Florida | 32610 | — |
| Samson Showalter Vascular Specialists | Sarasota | Florida | 34233 | — |
| Clinical Research Center | Sarasota | Florida | 34239 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Vascular & Surgery Assoc. | Sarasota | Florida | 34239 | — |
| Tampa General Hospital | Tampa | Florida | 33601 | — |
| Emory University School of Medicine Hospital | Atlanta | Georgia | 30322 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| Vascular Institute of Georgia | Atlanta | Georgia | 30342 | — |
| Atlanta VA Medical Center | Decatur | Georgia | 30033 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Veteran's Affairs Medical Center | Indianapolis | Indiana | 46202 | — |
| Our Lady of the Lake Regional Medical Center | Baton Rouge | Louisiana | 70808 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| University of Maryland Hospital | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| New England Medical Center Hospital | Boston | Massachusetts | 02111 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth-Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dept. of Surgery at Harvard Medical Faculty Physicians | Boston | Massachusetts | 02215 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| O.W. Brown, M.D. | Southfield | Michigan | 48075 | — |
| Steven D. Rimar, M.D. | Troy | Michigan | 48098 | — |
| St. Mary's Hospital | Rochester | Minnesota | 55902 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Dr. Randy Shafrtiz, Clinical Office | Holmdel | New Jersey | 07733 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07960 | — |
| Surgical Specialists of NJ, Morris Vascular Center | Morristown | New Jersey | 07960 | — |
| Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08903 | — |
| Umdnj-Rwjms | New Brunswick | New Jersey | 08903 | — |
| UMDNJ - New Jersey Medical School, University Hospital | Newark | New Jersey | — | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Kings County Hospital | Brooklyn | New York | 11203 | — |
| SUNY Downstate University Hospital of Brooklyn and Medical School | Brooklyn | New York | 11203 | — |
| Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| New York Presbyterian Hospital, Weill Medical College of Cornell University | New York | New York | 10021 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia Presbyterian Medical Center | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Montefiore Hospital | The Bronx | New York | 10467 | — |
| Gaston Memorial Hospital | Gastonia | North Carolina | 28054 | — |
| Pitt County Memorial Hospital | Greenville | North Carolina | 27834 | — |
| Department of Surgery, Division of Vascular Surgery, East Carolina University | Greenville | North Carolina | 27858 | — |
| Wake Forest University School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Flower Hospital | Sylvania | Ohio | 43560 | — |
| Jobst Vascular Center | Toledo | Ohio | 43606 | — |
| The Toledo Hospital | Toledo | Ohio | 43606 | — |
| Oregon Health Sciences University | Portland | Oregon | 97201 | — |
| Penn State College of Medicine | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Veterans Administration Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02905 | — |
| Medical University of South Carolina Hospital | Charleston | South Carolina | 29425 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| St. Thomas Medical | Nashville | Tennessee | 37205 | — |
| The Surgical Group, PLLC | Nashville | Tennessee | 37205 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| VAMC | Houston | Texas | 77030 | — |
| University Medical Center | Lubbock | Texas | 79415 | — |
| Texas Tech University Health Sciences Center | Lubbock | Texas | 79430 | — |
| Baptist Medical Center | San Antonio | Texas | 78205 | — |
| Peripheral Vascular Associates | San Antonio | Texas | 78215 | — |
| Northeast Baptist Hospital | San Antonio | Texas | 78217 | — |
| Peripheral Vascular Associates | San Antonio | Texas | 78217 | — |
| Pro-Research Group | San Antonio | Texas | 78224 | — |
| Southwest Texas Methodist Hospital | San Antonio | Texas | 78229 | — |
| University of Utah Hospital and Clinics | Salt Lake City | Utah | 84132 | — |
| Vascular and Transplant Specialists, Peripheral Vascular Laboratory | Chesapeake | Virginia | 23320 | — |
| Vascular and Transplant Specialsts, Peripheral and Vascular Laboratory | Chesapeake | Virginia | 23320 | — |
| Southampton Memorial Hospital | Franklin | Virginia | 23851 | — |
| Shore Memorial Hospital | Nassawadox | Virginia | 23413 | — |
| Chesapeake General Hospital | Norfolk | Virginia | 23502 | — |
| Vascular and Transplant Specialists, Peripheral Vascular Laboratory | Norfolk | Virginia | 23502 | — |
| Virginia Vascular Associates | Norfolk | Virginia | 23502 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Vascular and Transplant Specialists, Peripheral Vascular Laboratory | Norfolk | Virginia | 23510 | — |
| Carilion Roanoke Community Hospital | Roanoke | Virginia | 24014 | — |
| Carilion Roanoke Memorial Hospital | Roanoke | Virginia | 24014 | — |
| Jefferson Surgical Clinic | Roanoke | Virginia | 24016 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| VA Puget Sound Health Care System | Seattle | Washington | 98108 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Froedert Memorial Lutheran Hospital | Milwaukee | Wisconsin | 53226 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Clement J. Zablocki VAMC | Milwaukee | Wisconsin | 53295 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00041925, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 15, 2005 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00041925 live on ClinicalTrials.gov.