Evaluation of Dose-titration of Pramlintide During Initiation of Therapy in Patients Trying to Improve Glucose Control
Public ClinicalTrials.gov record NCT00042458. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Triple-Blind, Placebo-Controlled, Multicenter Study to Investigate the Safety of Pramlintide Treatment Employing Pramlintide Dose-Titration Followed by Insulin Dose Optimization in Subjects With Type 1 Diabetes Mellitus Who Have Not Achieved Glycemic Targets With Intensive Insulin Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, triple-blind, placebo-controlled, multicenter study to investigate the safety of pramlintide treatment using pramlintide dose-titration coupled with insulin adjustments in subjects with type 1 diabetes who are actively trying to improve their glycemic control.
Study identification
- NCT ID
- NCT00042458
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 296 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2002 (Type not available)
- Primary completion
- Mar 2003 (Actual)
- Completion
- Mar 2003 (Actual)
- Last update posted
- Sep 23, 2015
2002 – 2003
United States locations
- U.S. sites
- 33
- U.S. states
- 19
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ana Ventures LLC | Mesa | Arizona | 85204 | — |
| Phoenix Endocrinology Clinic, Ltd. | Phoenix | Arizona | 85006 | — |
| East Bay Clinical Trial Center | Concord | California | — | — |
| Valley Research | Fresno | California | — | — |
| UCSD Diabetes Research Center | San Diego | California | — | — |
| Diabetes Research Institute | San Mateo | California | — | — |
| Sansum Medical Research Institute | Santa Barbara | California | — | — |
| Diablo Clinical Research | Walnut Creek | California | — | — |
| Barbara Davis Center for Childhood Diabetes | Denver | Colorado | 80262 | — |
| MedStar Clinical Research Center | Washington D.C. | District of Columbia | — | — |
| Medical Research Unlimited | Aventura | Florida | 33180 | — |
| Medical Research Unlimited | Aventura | Florida | — | — |
| Internal Medicine Associates | Fort Myers | Florida | — | — |
| Suncoast Clinical Research | New Port Richey | Florida | — | — |
| Children's Clinic | Tallahassee | Florida | — | — |
| Atlanta Diabetes Associates | Atlanta | Georgia | — | — |
| St. James Diabetes Center | Chicago Heights | Illinois | 60411 | — |
| St. James Diabetes Center | Chicago Heights | Illinois | — | — |
| Indiana University Outpatient Clinical Research | Indianapolis | Indiana | — | — |
| University of Maryland Joslin Diabetes Center | Baltimore | Maryland | 21012 | — |
| Henry Ford Health System | Detroit | Michigan | — | — |
| Grand Rapids Associated Interns | Grand Rapids | Michigan | — | — |
| Radiant Research | St Louis | Missouri | 63141 | — |
| Mercury Street Medical | Butte | Montana | — | — |
| UNC Diabetes Care Center | Durham | North Carolina | 27713 | — |
| Ohio State Univ.-Division of Endocrinology, Diabetes | Columbus | Ohio | 43210 | — |
| Radiant Research | Portland | Oregon | — | — |
| Physicians for Clinical Research | Camp Hill | Pennsylvania | — | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | — | — |
| North Texas Clinical Research | Irving | Texas | — | — |
| Private Practice | Lufkin | Texas | 75904 | — |
| Private Practice | Lufkin | Texas | — | — |
| Rainier Clinical Research Center | Renton | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00042458, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 23, 2015 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00042458 live on ClinicalTrials.gov.