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Completed Phase 3 Interventional

Decitabine Versus Supportive Care in Adults With Advanced-stage MDS

ClinicalTrials.gov ID: NCT00043381

Public ClinicalTrials.gov record NCT00043381. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 2:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open-label, Phase III Trial of Decitabine (5-aza-2'Deoxycytidine) Versus Supportive Care in Adults With Advanced-stage Myelodysplastic Syndrome

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To compare the safety and efficacy profiles of decitabine to those of supportive care in adults with advanced-stage myelodysplastic syndrome (MDS)

Study identification

NCT ID
NCT00043381
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Astex Pharmaceuticals, Inc.
Industry
Enrollment
160 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2001
Primary completion
Oct 31, 2002
Completion
Mar 31, 2003
Last update posted
Aug 1, 2024

2001 – 2003

United States locations

U.S. sites
24
U.S. states
10
U.S. cities
20
Facility City State ZIP Site status
Alta Bates Comprehensive Cancer Center Berkeley California
City of Hope National Medical Center Duarte California
Scripps Clinic Escondido California
Loma Linda Univ. Cancer Center Loma Linda California
Univ. California San Francisco Medical School San Francisco California
University of Florida Gainesville Florida
H. Lee Moffitt Cancer Center Tampa Florida
James A. Haley Veteran's Hospital Tampa Florida
Rush Medical Center Chicago Illinois
University of Illinois at Chicago Chicago Illinois
Dana Farber Cancer Institute Boston Massachusetts
New England Medical Center Hospital Boston Massachusetts
University of Massachusetts Medical School Worcester Massachusetts
VA Medical Center Minneapolis Minnesota
Washington Univ. School of Medicine St Louis Missouri
Roswell Park Cancer Institute Buffalo New York
Memorial Sloan Kettering Cancer Center New York New York
Mount Sinai Medical Center New York New York
UNC Lineberger Comprehensive Cancer Center Chapel Hill North Carolina
Duke University Medical Center Durham North Carolina
The Memphis Cancer Center Memphis Tennessee
SW Regional Cancer Center (dba Central Texas Oncology Associates) Austin Texas
Texas Oncology Dallas Texas
MD Anderson Cancer Center Houston Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00043381, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 1, 2024 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00043381 live on ClinicalTrials.gov.

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