Treatment of Pediatric Hypertension With Altace Trial
Public ClinicalTrials.gov record NCT00044265. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Dose Escalation, Randomized, Double-blind Withdrawal Study of the Efficacy, Dose-response, and Safety of Ramipril for the Treatment of Hypertension in Children and Adolescents
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Ramipril is an ACE inhibitor that has been marketed in the US for the treatment of hypertension since 1991. It has been shown to be effective in reducing both systolic and diastolic blood pressure in adults when used once daily. ACE inhibitors are frequently used to treat hypertension in children, however ramipril has not been extensively tested in children, and information regarding the efficacy and safety would therefore be of benefit to children. This study is designed to demonstrate the efficacy and safety of ramipril in the treatment of hypertension in children ages 6 through 16 years.
Study identification
- NCT ID
- NCT00044265
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 310 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years to 16 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2002 (Type not available)
- Primary completion
- Not listed
- Completion
- Nov 2004 (Type not available)
- Last update posted
- Jun 7, 2012
2002 – 2004
United States locations
- U.S. sites
- 30
- U.S. states
- 18
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Sante Los Angeles | Los Angeles | California | 90010 | — |
| Neufeld Medical Group | Los Angeles | California | 90048 | — |
| UCLA Medical Center | Los Angeles | California | 90095 | — |
| Medical College of Georgia | Augusta | Georgia | 30912 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96813 | — |
| Nephrology and Hypertension Consultants | Park Ridge | Illinois | 60068 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| Univ of Missouri, Children's Mercy Hospital and Clinics | Kansas City | Missouri | 64108 | — |
| St. Louis Children's Hospital | St Louis | Missouri | 63110 | — |
| North Shore Univ Hospital c/o BRANY | Great Neck | New York | 11021 | — |
| Montefiore Medical Center c/o BRANY | The Bronx | New York | 10467 | — |
| Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| PCTI at Columbus Children's Hospital | Columbus | Ohio | 43205 | — |
| Oregon Health and Science University | Portland | Oregon | 97201 | — |
| Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| The Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| The Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Le Bonheur Children's Hospital - Univ of Tennessee | Memphis | Tennessee | 38103 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| University of Texas Medical Center | Houston | Texas | 77030 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00044265, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2012 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00044265 live on ClinicalTrials.gov.