Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer
Public ClinicalTrials.gov record NCT00044291. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether the first line combination hormonal therapy of an experimental drug, atamestane, plus an FDA-approved drug, toremifene (Fareston®), is more effective than another approved drug, letrozole (Femara®), in delaying the growth of breast cancer in postmenopausal patients with locally advanced or metastatic breast cancer, and whether the side effects of the combination are different from the side effects of letrozole.
Study identification
- NCT ID
- NCT00044291
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 865 participants
Conditions and interventions
Conditions
Interventions
- atamestane Drug
- toremifene Drug
- letrozole Drug
- aromatase inhibition Drug
- hormone therapy Procedure
- endocrine therapy Procedure
- antiestrogen therapy Procedure
Drug · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2002 (Type not available)
- Primary completion
- Jan 2006 (Actual)
- Completion
- Jan 2006 (Actual)
- Last update posted
- Jul 31, 2015
2002 – 2006
United States locations
- U.S. sites
- 17
- U.S. states
- 14
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Midwest Internal Medicine, PLLC | Lake Havasu City | Arizona | 86403 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85712 | — |
| California Cancer Care, Inc. | Greenbrae | California | 94904-2007 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Innovative Medical Research of South Florida Inc. | Miami Shores | Florida | 33138 | — |
| Georgia Cancer Specialists | Tucker | Georgia | 30084 | — |
| Maryland Hematology/Oncology Associates | Baltimore | Maryland | 21236 | — |
| Oncology Care Associates, PLLC | Saint Joseph | Michigan | 49085 | — |
| Kansas City Oncology and Hematology Group | Kansas City | Missouri | 64131 | — |
| Great Falls Clinic-Oncology West | Great Falls | Montana | 59405 | — |
| Slocum-Dickson Medical Group | New Hartford | New York | 13413 | — |
| Hematology Oncology Consultants, Inc. | Columbus | Ohio | 43235 | — |
| Oncology Consultants | Houston | Texas | 77024 | — |
| First Dynamic Healthcare Services, Inc. | Killeen | Texas | 76710 | — |
| Cache Valley Cancer Treatment & Research Clinic | Logan | Utah | 84341 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Western Washington Oncology Inc., P.S. | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00044291, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 31, 2015 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00044291 live on ClinicalTrials.gov.