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Terminated Phase 1 Interventional

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

ClinicalTrials.gov ID: NCT00045721

Public ClinicalTrials.gov record NCT00045721. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 1:31 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I Trial of GLIADEL and O(6)-Benzylguanine in Pediatric Patients With Recurrent Malignant Gliomas

Study identification

NCT ID
NCT00045721
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pediatric Brain Tumor Consortium
Network
Enrollment
3 participants

Conditions and interventions

Interventions

  • O6-benzylguanine Drug
  • polifeprosan 20 with carmustine implant Drug
  • adjuvant therapy Procedure
  • conventional surgery Procedure
  • neoadjuvant therapy Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
3 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2003
Primary completion
Jun 30, 2004
Completion
Jun 30, 2004
Last update posted
Oct 15, 2009

2003 – 2004

United States locations

U.S. sites
9
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
UCSF Comprehensive Cancer Center San Francisco California 94143-0372
Children's National Medical Center Washington D.C. District of Columbia 20010-2970
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston Massachusetts 02115
Duke Comprehensive Cancer Center Durham North Carolina 27710
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104-4318
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213
St. Jude Children's Research Hospital Memphis Tennessee 38105-2794
Texas Children's Cancer Center Houston Texas 77030-2399
Children's Hospital and Regional Medical Center - Seattle Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00045721, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 15, 2009 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00045721 live on ClinicalTrials.gov.

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