Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 3 Interventional Accepts healthy volunteers Results available

National Lung Screening Trial (NLST) Screening

ClinicalTrials.gov ID: NCT00047385

Public ClinicalTrials.gov record NCT00047385. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

National Lung Screening Trial A Randomized Trial Comparing Low-dose Helical CT With Chest Xray for Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Effective screening tests should help doctors detect lung cancer early and plan curative treatment. It is not yet known whether low-dose helical computed tomography (LDCT) screening is more effective than chest radiography (CXR) screening in reducing death from lung cancer. PURPOSE: Randomized clinical trial to compare the effectiveness of LDCT scan with that of CXR in screening individuals who are at high risk for developing lung cancer.

Study identification

NCT ID
NCT00047385
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
53,454 participants

Conditions and interventions

Eligibility (public fields only)

Age range
55 Years to 74 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2002
Primary completion
Sep 30, 2010
Completion
Sep 30, 2010
Last update posted
May 19, 2014

2002 – 2010

United States locations

U.S. sites
33
U.S. states
27
U.S. cities
32
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233
Univeristy of California, San Diego La Jolla California 92093-0658
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781
University of Colorado Denver Denver Colorado 80262
Georgetown University Medical Center Washington D.C. District of Columbia 20007
Mayo Clinic Jacksonville Florida 32224
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612-9497
Emory University School of Medicine Atlanta Georgia 30322
Pacific Health Research & Education Institute Honolulu Hawaii 96813
Northwestern University Chicago Illinois 60611
University of Iowa Iowa City Iowa 52242-1011
Jewish Hopsital Heart and Lung Institute Louisville Kentucky 40202
Ochsner Medical Foundation Hospital New Orleans Louisiana 70121
Johns Hopkins University Baltimore Maryland 21231
Brigham and Women's Hospital Boston Massachusetts 02115
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0942
Henry Ford Health System Detroit Michigan 48202
University of Minnesota School of Public Health Minneapolis Minnesota 55455
Mayo Clinic Cancer Center Rochester Minnesota 55905
Washington University School of Medicine St Louis Missouri 63108
Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03756-0002
Cancer Institute of New Jersey at Hamilton Hamilton New Jersey 08690
Wake Forest University Winston-Salem North Carolina 27106
St Elizabeth Health Center Youngstown Ohio 44504
University of Pennsylvania Medical Center Philadelphia Pennsylvania 19104
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15236
Brown University, Rhode Island Hospital Providence Rhode Island 02908-4735
Medical University of South Carolina Charleston South Carolina 29425
Vanderbilt University Nashville Tennessee 37232-6838
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009
University of Utah Health Sciences Center Salt Lake City Utah 84112
Marshfield Clinic Research Foundation Marshfield Wisconsin 54449

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00047385, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 19, 2014 · Synced Sep 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00047385 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →