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Completed Phase 3 Interventional Accepts healthy volunteers Results available

National Lung Screening Trial (NLST) Screening

ClinicalTrials.gov ID: NCT00047385

Public ClinicalTrials.gov record NCT00047385. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

National Lung Screening Trial A Randomized Trial Comparing Low-dose Helical CT With Chest Xray for Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Effective screening tests should help doctors detect lung cancer early and plan curative treatment. It is not yet known whether low-dose helical computed tomography (LDCT) screening is more effective than chest radiography (CXR) screening in reducing death from lung cancer. PURPOSE: Randomized clinical trial to compare the effectiveness of LDCT scan with that of CXR in screening individuals who are at high risk for developing lung cancer.

Study identification

NCT ID
NCT00047385
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
53,454 participants

Conditions and interventions

Eligibility (public fields only)

Age range
55 Years to 74 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2002 (Type not available)
Primary completion
Oct 2010 (Actual)
Completion
Oct 2010 (Actual)
Last update posted
May 20, 2014

2002 – 2010

United States locations

U.S. sites
33
U.S. states
27
U.S. cities
32
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233 —
Univeristy of California, San Diego La Jolla California 92093-0658 —
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781 —
University of Colorado Denver Denver Colorado 80262 —
Georgetown University Medical Center Washington D.C. District of Columbia 20007 —
Mayo Clinic Jacksonville Florida 32224 —
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612-9497 —
Emory University School of Medicine Atlanta Georgia 30322 —
Pacific Health Research & Education Institute Honolulu Hawaii 96813 —
Northwestern University Chicago Illinois 60611 —
University of Iowa Iowa City Iowa 52242-1011 —
Jewish Hopsital Heart and Lung Institute Louisville Kentucky 40202 —
Ochsner Medical Foundation Hospital New Orleans Louisiana 70121 —
Johns Hopkins University Baltimore Maryland 21231 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0942 —
Henry Ford Health System Detroit Michigan 48202 —
University of Minnesota School of Public Health Minneapolis Minnesota 55455 —
Mayo Clinic Cancer Center Rochester Minnesota 55905 —
Washington University School of Medicine St Louis Missouri 63108 —
Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03756-0002 —
Cancer Institute of New Jersey at Hamilton Hamilton New Jersey 08690 —
Wake Forest University Winston-Salem North Carolina 27106 —
St Elizabeth Health Center Youngstown Ohio 44504 —
University of Pennsylvania Medical Center Philadelphia Pennsylvania 19104 —
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15236 —
Brown University, Rhode Island Hospital Providence Rhode Island 02908-4735 —
Medical University of South Carolina Charleston South Carolina 29425 —
Vanderbilt University Nashville Tennessee 37232-6838 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009 —
University of Utah Health Sciences Center Salt Lake City Utah 84112 —
Marshfield Clinic Research Foundation Marshfield Wisconsin 54449 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00047385, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 20, 2014 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00047385 live on ClinicalTrials.gov.

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