Prialt (Ziconotide) In Severe Chronic Pain
Public ClinicalTrials.gov record NCT00047749. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study of Intrathecal Ziconotide in Adults With Severe Chronic Pain
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to understand the effects of intrathecal ziconotide (an experimental pain medication) when the dose is slowly increased over a 3-week period in patients with severe chronic pain. During the weaning phase, the study will also gather information about switching from other intrathecal or IT medication (slowly pumped directly into the space around the spine) to other systemic pain medication (by mouth or through the skin using a patch). After being weaned off current IT medication, patients will be placed on IT ziconotide or placebo (non-active substance) as well as being allowed a stable dose of systemic pain medications. Patients who complete this study may be eligible for long-term ziconotide therapy via extension protocol ELN92045-352.
Study identification
- NCT ID
- NCT00047749
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 220 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2002 (Type not available)
- Primary completion
- Not listed
- Completion
- Jun 2003 (Type not available)
- Last update posted
- Dec 14, 2015
2002 – 2003
United States locations
- U.S. sites
- 44
- U.S. states
- 29
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tennesee Valley Pain Consultants - Center For Pain Management | Huntsville | Alabama | 35801 | — |
| The Pain Center | Northport | Alabama | 35476 | — |
| Outcomes Research International | Tucson | Arizona | 85711 | — |
| The RC Goodman Pain Institute: Clinical Research | Fort Smith | Arkansas | 72901 | — |
| Hot Springs Mercy Pain Clinic | Hot Springs | Arkansas | 71913 | — |
| Innovative Spine Care | Little Rock | Arkansas | 72205 | — |
| Advanced Pain Medicine | Bakersfield | California | 93311 | — |
| Advanced Pain Institute | Duarte | California | 91010 | — |
| UCSD Medical Center, Thornton Hospital | La Jolla | California | 92037 | — |
| Abaci and Massey Pain Center | Los Gatos | California | 95032 | — |
| UCSF Pain Management Center | San Francisco | California | 94143-1654 | — |
| Pain Care Specialists | Colorado Springs | Colorado | 80907 | — |
| Clinical Pharmacology Services, Inc. | Tampa | Florida | 33617 | — |
| Georgia Medical Research Institute | Marietta | Georgia | 30060 | — |
| Rush Presbyterian - St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| University of Kentucky, Dept Anesthesiology | Lexington | Kentucky | 40536 | — |
| Johns Hopkins Hospital, Division of Pain Management | Baltimore | Maryland | 21205 | — |
| Arnold Pain Management | Boston | Massachusetts | 02215 | — |
| Edina Medical Pain Center | Edina | Minnesota | 55435 | — |
| Research Medical Center - Pain Institute | Kansas City | Missouri | 64132 | — |
| Yellowstone Medical Center East | Billings | Montana | 59101 | — |
| Huntington Center for Pain Treatment | Huntington | New York | 11743 | — |
| Weill Medical College of Cornell University | New York | New York | 10021 | — |
| Medical Pain Management of Central NY | Syracuse | New York | 13210 | — |
| Center For Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Pain Institute of Tulsa | Tulsa | Oklahoma | 74137 | — |
| Pain Consultants of Oregon | Eugene | Oregon | 97401 | — |
| Legacy Holladay Park Medical Center | Portland | Oregon | 97232 | — |
| Penn State University Hospital | Hershey | Pennsylvania | 17033 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Advanced Clinical Concepts | Temple | Pennsylvania | 19560 | — |
| Neurosurgery Foundation | Providence | Rhode Island | 02903 | — |
| MUSC, Neurological Surgery | Charleston | South Carolina | 29425 | — |
| Methodist Comprehensive Pain Institute | Memphis | Tennessee | 38104 | — |
| Clinical Research Associates, Inc. | Nashville | Tennessee | 37203 | — |
| University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| Texas Tech University HSC | Lubbock | Texas | 79430 | — |
| Consultants in Pain Research | San Antonio | Texas | 78217 | — |
| Alpine Pain and Addiction Medicine | Salt Lake City | Utah | 84107 | — |
| Advanced Pain Management and Rehabilitation | Virginia Beach | Virginia | 23454 | — |
| University of Washington Medical Center - Pain Center | Seattle | Washington | 98195 | — |
| Center for Pain Relief | Charleston | West Virginia | 25301 | — |
| Cardinal Clinical Research Center | Cudahy | Wisconsin | 53110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00047749, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2015 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00047749 live on ClinicalTrials.gov.