ClinicalTrials.gov record
Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass
ClinicalTrials.gov ID: NCT00048308
Public ClinicalTrials.gov record NCT00048308. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
During a heart bypass procedure, a substance called "complement" is released by the body. This complement causes inflammation, which can lead to side effects such as chest pain, heart attacks, heart failure, or impairment of memory, language and motor skills. The purpose of this study is to find out if the study drug (pexelizumab), which blocks complement release, can reduce such side effects and be taken safely.
Study identification
- NCT ID
- NCT00048308
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,000 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2002 (Actual)
- Primary completion
- Mar 2003 (Actual)
- Completion
- Not listed
- Last update posted
- Feb 23, 2017
Started 2002
United States locations
- U.S. sites
- 168
- U.S. states
- 38
- U.S. cities
- 123
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Baptist Medical Center Cardiology | Birmingham | Alabama | 35211 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35249-6880 | — |
| IMC-Diagnostic and Medical Clinic | Mobile | Alabama | 36604 | — |
| Desert Samaritan - Lutheran Heart | Mesa | Arizona | 85202 | — |
| Good Samaritan Regional Medical Center | Phoenix | Arizona | 85006 | — |
| Saguaro Clinical Research | Tucson | Arizona | 85712 | — |
| Southern Arizona VAMC | Tucson | Arizona | 85723 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Sparks Regional Medical Center | Fort Smith | Arkansas | 72901 | — |
| University of Arkansas | Little Rock | Arkansas | 72205 | — |
| Brotman Medical Center | Beverly Hills | California | 90210 | — |
| Cardiovascular Associates of the Peninsula | Burlingame | California | 94401 | — |
| Seton Medical Center | Daly City | California | 94015 | — |
| St. Jude Medical Center | Fullerton | California | 92835 | — |
| Apex Cardiology | Inglewood | California | 90301 | — |
| Huntington Memorial Hospital | Los Angeles | California | 90033 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| St. Vincent's Hospital | Los Angeles | California | 90057 | — |
| University of California - Los Angeles | Los Angeles | California | 90095 | — |
| Crozer-Chester Medical Center | Oakland | California | 94609-3102 | — |
| Tri-City Medical Center | Oceanside | California | 92056 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| San Diego Cardiac Center | San Diego | California | 92123 | — |
| Kaiser Foundation Hospital | San Francisco | California | 94115 | — |
| UCSF Moffitt-Long Hospital | San Francisco | California | 94143 | — |
| South Denver Cardiology Associates | Denver | Colorado | 80111 | — |
| Western Cardiology Associates | Denver | Colorado | 80218 | — |
| Heart and Vascular Clinic of Northern CO | Fort Collins | Colorado | 80528 | — |
| St. Vincent's Medical Center | Bridgeport | Connecticut | 06606 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Christiana Care Health Services | Newark | Delaware | 19718 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Cardiology Associates | Washington D.C. | District of Columbia | 20010 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| VA Medical Center - Washington DC | Washington D.C. | District of Columbia | 20422 | — |
| Florida Cardiovascular Research | Atlantis | Florida | 33462 | — |
| Morton Plan Mease Health Care | Clearwater | Florida | 33756 | — |
| Heart Group Research | Fort Lauderdale | Florida | 33308 | — |
| Gulf Bay Cardiovascular and Thoracic Associates | Hudson | Florida | 34563 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| MIMA Century Research Associates | Melbourne | Florida | 32901 | — |
| Brevard Cardiology Group, PA | Merritt Island | Florida | 32953 | — |
| Medical Research Unlimited | Miami | Florida | 33125 | — |
| Florida Heart Institute at Florida Hospital | Orlando | Florida | 32803 | — |
| Orlando Heart Center | Orlando | Florida | 32806 | — |
| Cardiology Consultants | Pensacola | Florida | 32504 | — |
| Ford Research Center | Pensacola | Florida | 32514 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Northside Hospital ans Heart Institute | St. Petersburg | Florida | 33709 | — |
| Tallahassee Memorial Regional Medical Center | Tallahassee | Florida | 32308 | — |
| Pepin Heart and Vascular Institute | Tampa | Florida | 33613 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| St. Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| University Hospital | Augusta | Georgia | 30901 | — |
| VA Medical Center- Atlanta | Decatur | Georgia | 30033 | — |
| VA Medical Center - Dubin | Macon | Georgia | 31208 | — |
| Straub Clinic and Hospital | Honolulu | Hawaii | 96813-3009 | — |
| Kaiser Permanente Medical Center | Honolulu | Hawaii | 96819 | — |
| Northwestern Univ. Medical Center | Chicago | Illinois | 60611 | — |
| Northwestern University Medical Center | Chicago | Illinois | 60611 | — |
| University of Illinois - Chicago | Chicago | Illinois | 60612 | — |
| Evanston Northwestern Healthcare Evanston Hospital | Evanston | Illinois | 60201 | — |
| Indiana Ohio Heart | Fort Wayne | Indiana | 46804 | — |
| Community Hospital | Indianapolis | Indiana | 46219 | — |
| St. Vincent's Medical Center | Indianapolis | Indiana | 46260 | — |
| Iowa Heart Center - Laurel | Des Moines | Iowa | 50314 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas City Medical Center | Kansas City | Kansas | 66160-7378 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| University of Louisville | Louisville | Kentucky | 40292 | — |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| Turuo Infirmary | New Orleans | Louisiana | 70115 | — |
| Methodist Hospital | New Orleans | Louisiana | 70118 | — |
| Alton Ochsner Medical Foundation - Brent House | New Orleans | Louisiana | 70121 | — |
| Cardiac Centers of Louisiana | Shreveport | Louisiana | 711033 | — |
| Cardiovascular Institute of the South | Thibodaux | Louisiana | 70301 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Union Memorial Hospital | Baltimore | Maryland | 21218 | — |
| Washington Adventist Hospital | Takoma Park | Maryland | 20912 | — |
| Midatlantic Cardiovascular Associates | Towson | Maryland | 21204 | — |
| St. Joseph's Hospital | Towson | Maryland | 21204 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Womens Hospital | Boston | Massachusetts | 02115 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Massachusetts | Worcester | Massachusetts | 01655 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| McLaren Regional Medical Center | Flint | Michigan | 48532 | — |
| Thoracic and Cardiovascular Institute | Lansing | Michigan | 48919 | — |
| West Shore Cardiology Research Department | Muskegon | Michigan | 46444 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Covenant Medical Center | Saginaw | Michigan | 48602 | — |
| St. Luke's Hospital-Duluth | Duluth | Minnesota | 55805 | — |
| St. Mary's Duluth Health System | Duluth | Minnesota | 55805 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Park Nicollet Medical Center | Minneapolis | Minnesota | 55416 | — |
| North Memorial Hospital | Robbinsdale | Minnesota | 55422 | — |
| Park Nicollet Health Research Center | Saint Louis Park | Minnesota | 55426 | — |
| Mississippi Center for Clinical Research | Jackson | Mississippi | 32216 | — |
| Cardiology diagnostics, Ltd. | City of Saint Peters | Missouri | 63376 | — |
| St. Luke's Hospital - Mid-America Heart Institute | Kansas City | Missouri | 64111 | — |
| Christian North East Hospital | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Cardiovascular Associates of the Delaware Valley | Haddon Heights | New Jersey | 08035 | — |
| Garden State Cardiology | Paramus | New Jersey | 07652 | — |
| Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| United Health Services | Johnson City | New York | 13790 | — |
| New York Presbyterian Hospital | New York | New York | 10021 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Albert Einstein Hospital | The Bronx | New York | 10461 | — |
| Westchester County Medical Center | Valhalla | New York | 10595 | — |
| Asheville Cardiothoracic Surgeons | Asheville | North Carolina | 28803 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| West forest School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| Akron General Medical Center | Akron | Ohio | 44307 | — |
| Summa Health Systems | Akron | Ohio | 44309 | — |
| Good Samaritan Hospital | Cincinnati | Ohio | 45219 | — |
| Sterling Research Group | Cincinnati | Ohio | 45219 | — |
| Good Samaritan Hospital -Seton Center | Cincinnati | Ohio | 45220 | — |
| Tri Health Bethesda North Hospital | Cincinnati | Ohio | 45242 | — |
| University Hopital of Cleveland | Cleveland | Ohio | 44106 | — |
| Mt. Carmel West | Columbus | Ohio | 43222 | — |
| Dayton Heart Center | Dayton | Ohio | 45414 | — |
| North Ohio Heart Center | Sandusky | Ohio | 44870 | — |
| Oklahoma Foundation for Cardiovascular Research | Oklahoma City | Oklahoma | 73104 | — |
| University of Oklahoma | Oklahoma City | Oklahoma | 73104 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Northwest Surgical Associates | Portland | Oregon | 97210 | — |
| Legacy Good Samaritan Hospital | Portland | Oregon | 97232 | — |
| The Heart Center | Doylestown | Pennsylvania | 18901 | — |
| North Memorial Pain Institute | Philadelphia | Pennsylvania | 19102 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Guthrie Clinical Research | Sayre | Pennsylvania | 18840 | — |
| Chester County Cardiovascular Center | West Chester | Pennsylvania | 19380 | — |
| The Chattanooga Heart Institute Cardiovascular Group, P.C. | Chattanooga | Tennessee | 37404 | — |
| Baptist Memorial Hospital | Memphis | Tennessee | 38120 | — |
| Parkway Cardiovascular Associates | Oak Ridge | Tennessee | 37830 | — |
| Brackenridge Hospital | Austin | Texas | 78701 | — |
| Seton Medical Center | Austin | Texas | 78705 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
| VA Medical Center - Houston | Houston | Texas | 77030 | — |
| Texas Tech University Health Center | Lubbock | Texas | 79430 | — |
| South Texas Cardiovascular Consultants Clinical Research Center | San Antonio | Texas | 78229 | — |
| South Texas VA Health Care | San Antonio | Texas | 78284 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Fletcher Allen Health Care | Burlington | Vermont | 05401 | — |
| Cardiovascular and Thoracic Surgery Associates | Arlington | Virginia | 22205 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22043 | — |
| Mary Washington Hospital | Fredericksburg | Virginia | — | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Carillion Roanoke Hospital | Roanoke | Virginia | 24014 | — |
| VA-Medical Center -Seattle Cardiology | Seattle | Washington | 98108 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| FHS Research Center | Tacoma | Washington | 98405 | — |
| Tacoma General Hospital | Tacoma | Washington | 98405 | — |
| Camcare Health Education & Research Institute | Charleston | West Virginia | 25304 | — |
| Appleton Medical Center | Appleton | Wisconsin | 54911 | — |
| Gundersen-Lutheran Hospital | La Crosse | Wisconsin | 54601 | — |
| Wisconsin Center for Clinical Research | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53295 | — |
| Cardiovascular Research and Education Foundation, Inc. | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00048308, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 23, 2017 · Synced Nov 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00048308 live on ClinicalTrials.gov.