A Phase III Study of Abatacept (BMS-188667) in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
Public ClinicalTrials.gov record NCT00048568. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study and Open-Label Study to Evaluate the Efficacy and Safety of Abatacept in Combination Therapy With Methotrexate Versus Methotrexate Alone in Subjects With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Short Term: The purpose of this clinical research study is to learn if abatacept (BMS-188667) in combination with methotrexate is better than methotrexate alone in participants that have active rheumatoid arthritis and are not responding to methotrexate. The safety of this treatment will also be studied. Long Term Extension: The purpose of this amendment is to provide participants who have completed the initial 12-month double-blind treatment period the opportunity to receive open label treatment with active drug treatment until abatacept is approved in the local country or until clinical development has been discontinued.
Study identification
- NCT ID
- NCT00048568
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,250 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2002 (Type not available)
- Primary completion
- Oct 2009 (Actual)
- Completion
- Oct 2009 (Actual)
- Last update posted
- Dec 5, 2011
2002 – 2009
United States locations
- U.S. sites
- 48
- U.S. states
- 24
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution | Birmingham | Alabama | — | — |
| Local Institution | Huntsville | Alabama | — | — |
| Local Institution | Mobile | Alabama | — | — |
| Local Institution | Phoenix | Arizona | — | — |
| Local Institution | Scottsdale | Arizona | — | — |
| Local Institution | Corona | California | — | — |
| Local Institution | Irvine | California | — | — |
| Local Institution | La Jolla | California | — | — |
| Local Institution | Long Beach | California | — | — |
| Local Institution | Rancho Mirage | California | — | — |
| Local Institution | Aurora | Colorado | — | — |
| Local Institution | Colorado Springs | Colorado | — | — |
| Local Institution | Denver | Colorado | — | — |
| Local Institution | Hamden | Connecticut | — | — |
| Local Institution | Washington D.C. | District of Columbia | — | — |
| Local Institution | Fort Lauderdale | Florida | — | — |
| Local Institution | Gainsville | Florida | — | — |
| Local Institution | Palm Harbor | Florida | — | — |
| Local Institution | Sarasota | Florida | — | — |
| Local Institution | St. Petersburg | Florida | — | — |
| Local Institution | Chicago | Illinois | — | — |
| Local Institution | Rockford | Illinois | — | — |
| Local Institution | Wichita | Kansas | — | — |
| Local Institution | Coeur d'Alene | Maryland | — | — |
| Local Institution | Cumberland | Maryland | — | — |
| Local Institution | Springfield | Massachusetts | — | — |
| Local Institution | Duluth | Minnesota | — | — |
| Local Institution | Lincoln | Nebraska | — | — |
| Local Institution | New Brunswick | New Jersey | — | — |
| Local Institution | Albuquerque | New Mexico | — | — |
| Local Institution | Albany | New York | — | — |
| Local Institution | Binghamton | New York | — | — |
| Local Institution | Mineola | New York | — | — |
| Local Institution | New York | New York | — | — |
| Local Institution | Syracuse | New York | — | — |
| Local Institution | The Bronx | New York | — | — |
| Local Institution | Wilmington | North Carolina | — | — |
| Local Institution | Cincinnati | Ohio | — | — |
| Local Institution | Oklahoma City | Oklahoma | — | — |
| Local Institution | Duncansville | Pennsylvania | — | — |
| Local Institution | Norristown | Pennsylvania | — | — |
| Local Institution | Sellersville | Pennsylvania | — | — |
| Local Institution | Willow Grove | Pennsylvania | — | — |
| Local Institution | North Charleston | South Carolina | — | — |
| Local Institution | Austin | Texas | — | — |
| Local Institution | San Antonio | Texas | — | — |
| Local Institution | Arlington | Virginia | — | — |
| Local Institution | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00048568, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 5, 2011 · Synced Nov 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00048568 live on ClinicalTrials.gov.