HORIZON-PFT: Pivotal Fracture Trial
Public ClinicalTrials.gov record NCT00049829. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
HORIZON-PFT (Pivotal Fracture Trial) will study the effect of zoledronic acid, given once per year, on the treatment of osteoporosis in women past menopause. Hip and vertebral fractures are the most devastating consequences of osteoporosis. HORIZON-PFT is designed to determine the benefits of zoledronic acid in fracture reduction at both the hip and spine.
Study identification
- NCT ID
- NCT00049829
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 7,700 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 65 Years to 89 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2002 (Type not available)
- Primary completion
- Jun 2006 (Actual)
- Completion
- Not listed
- Last update posted
- Nov 2, 2011
Started 2002
United States locations
- U.S. sites
- 59
- U.S. states
- 30
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35205 | — |
| Arizona Arthritis Research | Paradise Valley | Arizona | 85253 | — |
| Southern Arizona VA | Tucson | Arizona | 85723 | — |
| University of Arkansas for Medical Science | Little Rock | Arkansas | 72205 | — |
| Osteoporosis Medical Center | Beverly Hills | California | 90211 | — |
| Orthopaedic Hospital | Los Angeles | California | 90007 | — |
| The Foundation for Osteoporosis Research and Education | Oakland | California | 94612 | — |
| University of California Davis- Gen Med Research | Sacramento | California | 95817 | — |
| Osteoporosis Prevention Center | San Diego | California | 92103 | — |
| Radiant Research- San Diego | San Diego | California | 92108 | — |
| Diablo Clinical Research, Inc | Walnut Creek | California | 94598 | — |
| Colorado Center for Bone Research | Lakewood | Colorado | 80227 | — |
| Longmont Medical Research Network | Longmont | Colorado | 80501 | — |
| Northeast Clinical Research | Hamden | Connecticut | 06518-3272 | — |
| Health Core | Newark | Delaware | 19713-2072 | — |
| CRA Research | Fort Lauderdale | Florida | 33334 | — |
| Anchor Research Center | Naples | Florida | 34102 | — |
| Sarasota Arthritis Center | Sarasota | Florida | 34239 | — |
| Radiant | Stuart | Florida | 34996 | — |
| Comprehensive Clinical Trials, LLC | West Palm Beach | Florida | 33409 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| United Osteoporosis Centers (UOC) | Gainesville | Georgia | 30501 | — |
| Northwestern University Center for Clinical Research | Chicago | Illinois | 60611 | — |
| School of Medicine | Indianapolis | Indiana | 46202 | — |
| Medical Specialists | Munster | Indiana | 46321 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| Center for Arthritis and Osteoporosis | Elizabethtown | Kentucky | 42701 | — |
| Maine Center for Osteoporosis Research and Education | Bangor | Maine | 04401 | — |
| Osteoporosis Clinical Trial Center | Hagerstown | Maryland | 21740 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Clinical Pharmacology Study Groups | Worcester | Massachusetts | 01610 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Arthritis Regional Research Center | Mercerville | New Jersey | 08619 | — |
| Phoenix OB-GYN Associates, LLC | Moorestown | New Jersey | 08057 | — |
| New Mexico Clinical Research and Osteoporosis Center, Inc | Albuquerque | New Mexico | 87106 | — |
| Endwell Family Physicians | Endwell | New York | 13760 | — |
| Winthrop U Hospital | Mineola | New York | 11501 | — |
| Internal Medicine Associates | Fargo | North Dakota | 58104 | — |
| University of Cincinnati Bone Health and Osteoporosis Center | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Oregon Health and Science University | Portland | Oregon | 97201 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Einstein | Philadelphia | Pennsylvania | 19115 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19131 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15261 | — |
| Radiant | Wyomissing | Pennsylvania | 19610 | — |
| Rhode Island Hospital, Osteoporosis Research/ Bone Density Unit | Providence | Rhode Island | 02903 | — |
| Roger William Medical Center | Providence | Rhode Island | 02908 | — |
| Avera Research Institute | Sioux Falls | South Dakota | 57105 | — |
| University of Tennessee Health Science | Memphis | Tennessee | 38105 | — |
| West Cancer Clinic | Memphis | Tennessee | 38120 | — |
| Diabetes Regional Research Center | Midland | Texas | 79705 | — |
| Sam Clinical Research Center | San Antonio | Texas | 78229 | — |
| University of Texas Health Center at Tyler -Center for Clinical Research | Tyler | Texas | 75708 | — |
| Hampton Roads Center for Clinical Research, Inc | Norfolk | Virginia | 23502 | — |
| McGuire Veterans Affairs Medical Center | Richmond | Virginia | 23249 | — |
| VA Commonwealth University | Richmond | Virginia | 23298 | — |
| Osteoporosis Research Unit | Seattle | Washington | 98144 | — |
| The Physicians Clinic | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00049829, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 2, 2011 · Synced Nov 3, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00049829 live on ClinicalTrials.gov.