Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis Patients
Public ClinicalTrials.gov record NCT00050232. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Pseudobulbar Affect is a condition characterized by frequent episodes of laughing and crying out of proportion. Other terms used to describe this condition include emotional lability, emotionalism, emotion incontinence, emotional discontrol, excessive emotionalism and pathological laughing and crying. AVP-923 is a new experimental drug that may assist in the reduction of uncontrolled episodes. This study will test the safety and efficacy of AVP-923 in the treatment of MS patients suffering from pseudobulbar affect.
Study identification
- NCT ID
- NCT00050232
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 96 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 68 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2002 (Type not available)
- Primary completion
- Jun 2004 (Actual)
- Completion
- Jun 2004 (Actual)
- Last update posted
- Jul 14, 2016
2002 – 2004
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| George Washington University Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| Neurological Associates | Fort Lauderdale | Florida | 33334 | — |
| Neurology & Headache Specialist of Atlanta, L.L.C. | Decatur | Georgia | 30033 | — |
| Radiant Research Alexian Brothers | Elk Grove Village | Illinois | 60007 | — |
| Consultants in Neurology LTD | Northbrook | Illinois | 60062 | — |
| Advanced Neurology Specialists | Great Falls | Montana | 59405 | — |
| Neurological Associates, P.C. | Lincoln | Nebraska | 68506 | — |
| Upstate Clinical Research | Albany | New York | 12205 | — |
| DENT Neurologic Group L.L.P. | Amherst | New York | 14266 | — |
| Hospital for Joint Diseases - MS Care Center | New York | New York | 10003 | — |
| Institute for Human Performance | Syracuse | New York | 13210 | — |
| Raleigh Neurology Associates, P.A. | Raleigh | North Carolina | 27607 | — |
| NeuroCare Center, Inc. | Canton | Ohio | 44718 | — |
| Leheigh Valley Neurosciences and Pain Research Center | Allentown | Pennsylvania | 18103 | — |
| Westmorland Neurology | Greensburg | Pennsylvania | 15601 | — |
| Neurological Associates of Delaware Valley | Upland | Pennsylvania | 19013 | — |
| FACH-UHC Department of Neurological Services | Burlington | Vermont | 05401 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| Neurology and Neurosurgery Associates of Tacoma | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00050232, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 14, 2016 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00050232 live on ClinicalTrials.gov.