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Completed Phase 2 Interventional Results available

A Phase II Study Comparing Low- and High-Dose Alemtuzumab and High-Dose Rebif® in Patients With Early, Active Relapsing-Remitting Multiple Sclerosis

ClinicalTrials.gov ID: NCT00050778

Public ClinicalTrials.gov record NCT00050778. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 1:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Randomized, Open-Label, Three-Arm Study Comparing Low- and High-Dose Alemtuzumab and High-Dose Subcutaneous Interferon Beta-1a (Rebif®) in Patients With Early, Active Relapsing-Remitting Multiple Sclerosis

Study identification

NCT ID
NCT00050778
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genzyme, a Sanofi Company
Industry
Enrollment
334 participants

Conditions and interventions

Interventions

  • Interferon beta-1a Biological
  • Alemtuzumab 12 mg Biological
  • Alemtuzumab 24 mg Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 50 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2002
Primary completion
Aug 31, 2007
Completion
Dec 31, 2009
Last update posted
Jan 7, 2015

2002 – 2010

United States locations

U.S. sites
31
U.S. states
19
U.S. cities
30
Facility City State ZIP Site status
Mayo Clinic Scottsdale Arizona Scottsdale Arizona 85259
Clinical Trials, Inc Little Rock Arkansas 72205
East Bay Physicians Medical Group Berkeley California 94705
Nerve Pro Research Irvine California 92618
Neuro-Therapeutics, Inc. Pasadena California 91105
Neurological Research Institute of the East Bay Walnut Creek California 938-1343
Neurologic Research Institute/Mile High Research Center Denver Colorado 80218
Neurological Service of Orlando Orlando Florida 32806
Neurological Associates/ Research Dept. Pompano Beach Florida 33060
Neurology Clinical Research, Inc. Sunrise Florida 3335-6637
Axiom Clinical Research of Florida Tampa Florida 33609
Medical Research and Health Education Columbus Georgia 31909
Consultants in Neurology, Ltd Northbrook Illinois 60062
Fort Wayne Neurological Center Fort Wayne Indiana 46805
Associate in Neurology Lexington Kentucky 40503
University of Maryland -Maryland Center for MS Baltimore Maryland 21201
Wayne State University Department of Neurology Detroit Michigan 48201
Michigan Institute for Neurological Disorders Farmington Hills Michigan 48334
Michigan Medical P.C. Neurology Grand Rapids Michigan 49525
Mayo Clinic Rochester Department of Neurology Rochester Minnesota 55905
Nevada Neurological Consultants, Ltd. Las Vegas Nevada 89102
University Hospital an Medical Center Stony Brook New York 11794
ALL-Trials Clinical Research, LLC Winston-Salem North Carolina 27103
Neurological Associates of Tulsa, Inc Tulsa Oklahoma 74137
Neurosciencies and Pain Research Allentown Pennsylvania 18103-6296
Neurology, PC Knoxville Tennessee 37934
Baylor College of Medicine Houston Texas
Dallas Neurological Associate Richardson Texas 75080
Central Texas Neurology Consultants PA Round Rock Texas 78681
Integra Clinical Research, LLC San Antonio Texas 78231
Neurology Center of San Antonio San Antonio Texas 78258

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00050778, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 7, 2015 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00050778 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →