Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients
Public ClinicalTrials.gov record NCT00050895. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Open-Label Comparison of Lopinavir/Ritonavir Plus Efavirenz Versus Lopinavir/Ritonavir Plus 2 NRTIs Versus Efavirenz Plus 2 NRTIs as Initial Therapy for HIV-1 Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
With new strategies and drugs available, many different regimens exist for the treatment of HIV. The purpose of this study is to compare three different anti-HIV drug regimens as first-time treatments for HIV infection.
Study identification
- NCT ID
- NCT00050895
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 775 participants
Conditions and interventions
Conditions
Interventions
- Lopinavir/ritonavir Drug
- Efavirenz Drug
- Stavudine Drug
- Zidovudine Drug
- Lamivudine Drug
- Tenofovir disoproxil fumarate Drug
Drug
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Mar 2006 (Actual)
- Last update posted
- Nov 1, 2021
Ends 2006
United States locations
- U.S. sites
- 59
- U.S. states
- 22
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Therapeutics CRS | Birmingham | Alabama | 35924 | — |
| USC CRS | Los Angeles | California | 90033-1079 | — |
| UCLA CARE Center CRS | Los Angeles | California | 90095-1793 | — |
| Stanford CRS | Palo Alto | California | 94305-5107 | — |
| UC Davis Medical Center | Sacramento | California | 95814 | — |
| Univ. of California Davis Med. Ctr., ACTU | Sacramento | California | — | — |
| Ucsd, Avrc Crs | San Diego | California | 92103 | — |
| Ucsf Aids Crs | San Francisco | California | 94110 | — |
| Santa Clara Valley Med. Ctr. | San Jose | California | 94305-5107 | — |
| San Mateo County AIDS Program | San Mateo | California | 94305-5107 | — |
| Harbor-UCLA Med. Ctr. CRS | Torrance | California | 90502-2052 | — |
| University of Colorado Hospital CRS | Aurora | Colorado | 80262-3706 | — |
| Georgetown University CRS (GU CRS) | Washington D.C. | District of Columbia | 20007 | — |
| Univ. of Miami AIDS CRS | Miami | Florida | 33136 | — |
| The Ponce de Leon Ctr. CRS | Atlanta | Georgia | 30308 | — |
| Univ. of Hawaii at Manoa, Leahi Hosp. | Honolulu | Hawaii | 96816 | — |
| Northwestern University CRS | Chicago | Illinois | 60611-3015 | — |
| Rush Univ. Med. Ctr. ACTG CRS | Chicago | Illinois | 60612-3806 | — |
| Cook County Hosp. CORE Ctr. | Chicago | Illinois | 60612 | — |
| Methodist Hosp. of Indiana | Indianapolis | Indiana | 46202-1261 | — |
| Indiana Univ. School of Medicine, Infectious Disease Research Clinic | Indianapolis | Indiana | 46202-5250 | — |
| Indiana Univ. School of Medicine, Wishard Memorial | Indianapolis | Indiana | 46202 | — |
| Univ. of Iowa Healthcare, Div. of Infectious Diseases | Iowa City | Iowa | 52242-1201 | — |
| IHV Baltimore Treatment CRS | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Adult AIDS CRS | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital ACTG CRS | Boston | Massachusetts | 02114 | — |
| Bmc Actg Crs | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Med. Ctr., ACTG CRS | Boston | Massachusetts | 02215 | — |
| Brigham and Women's Hosp. ACTG CRS | Boston | Massachusetts | 02215 | — |
| SSTAR, Family Healthcare Ctr. | Fall River | Massachusetts | — | — |
| University of Minnesota, ACTU | Minneapolis | Minnesota | 55455-0392 | — |
| St. Louis ConnectCare, Infectious Diseases Clinic | St Louis | Missouri | 63108-2138 | — |
| Washington U CRS | St Louis | Missouri | 63108-2138 | — |
| Univ. of Nebraska Med. Ctr., Durham Outpatient Ctr. | Omaha | Nebraska | 68198-5130 | — |
| SUNY - Buffalo, Erie County Medical Ctr. | Buffalo | New York | 14215 | — |
| Beth Israel Med. Ctr., ACTU | New York | New York | 10003 | — |
| NY Univ. HIV/AIDS CRS | New York | New York | 10016-6481 | — |
| Cornell CRS | New York | New York | 10021 | — |
| Columbia Univ., HIV Prevention and Treatment Medical Ctr. | New York | New York | 10032-3784 | — |
| HIV Prevention & Treatment CRS | New York | New York | — | — |
| Weill Med. College of Cornell Univ., The Cornell CTU | New York | New York | — | — |
| Univ. of Rochester ACTG CRS | Rochester | New York | 14642-0001 | — |
| AIDS Care CRS | Rochester | New York | — | — |
| McCree McCuller Wellness Ctr. at the Connection, Infectious Disease Unit | Rochester | New York | — | — |
| Unc Aids Crs | Chapel Hill | North Carolina | 27514 | — |
| Duke Univ. Med. Ctr. Adult CRS | Durham | North Carolina | 27710 | — |
| Wake County Health and Human Services CRS | Raleigh | North Carolina | — | — |
| Univ. of Cincinnati CRS | Cincinnati | Ohio | 45267-0405 | — |
| Case CRS | Cleveland | Ohio | 44106-5083 | — |
| MetroHealth CRS | Cleveland | Ohio | 44109-1998 | — |
| Cleveland Clinic Foundation, Div. of Medicine, Infectious Diseases | Cleveland | Ohio | 44109-5083 | — |
| The Ohio State Univ. AIDS CRS | Columbus | Ohio | 43210-1282 | — |
| Univ. of Pennsylvania Health System, Presbyterian Med. Ctr. | Philadelphia | Pennsylvania | 19104 | — |
| Hosp. of the Univ. of Pennsylvania CRS | Philadelphia | Pennsylvania | 19401 | — |
| Pitt CRS | Pittsburgh | Pennsylvania | 15213-2582 | — |
| Rhode Island Hosp. | Providence | Rhode Island | 02906 | — |
| The Miriam Hosp. ACTG CRS | Providence | Rhode Island | 02906 | — |
| Vanderbilt Therapeutics CRS | Nashville | Tennessee | 37203 | — |
| University of Washington AIDS CRS | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00050895, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 1, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00050895 live on ClinicalTrials.gov.