Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
Public ClinicalTrials.gov record NCT00051636. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-blind, Safety and Efficacy Trial With Intravenous Zoledronic Acid for the Treatment of Paget's Disease of Bone Using Risedronate as a Comparator, Including an Extended Observational Period
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The core study looked at the effect of Zoledronic Acid given once as an intravenous (i.v.) infusion compared to 60 days of oral Risedronate in patients with Paget's disease of bone. The effect was demonstrated in the reduction of serum alkaline phosphatase (SAP). The extended observation period included participants of the core study who responded to treatment.
Study identification
- NCT ID
- NCT00051636
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 172 participants
Conditions and interventions
Conditions
Interventions
- Zoledronic Acid Drug
- Risedronate Drug
- Placebo to Risedronate Drug
- Placebo to Zoledronic Acid Drug
- Calcium and Vitamin D Dietary Supplement
Drug · Dietary Supplement
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2001 (Type not available)
- Primary completion
- Mar 2004 (Actual)
- Completion
- Apr 2011 (Actual)
- Last update posted
- May 15, 2012
2001 – 2011
United States locations
- U.S. sites
- 12
- U.S. states
- 10
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novartis Investigative Site | Santa Monica | California | 90414 | — |
| Novartis Investigative Site | Lakewood | Colorado | 80227 | — |
| Novartis Investigative Site | Boca Raton | Florida | 33433 | — |
| Novartis Investigative Site | Miami | Florida | 33101 | — |
| Novartis Investigative site | Maywood | Illinois | 60153 | — |
| Novartis investigative site | Worcester | Massachusetts | 01601 | — |
| Novartis investigative site | Detroit | Michigan | 48021 | — |
| Novartis Investigative Site | New York | New York | 10029 | — |
| Novartis investigative site | Syracuse | New York | 13210 | — |
| Novartis investigative site | Durham | North Carolina | 27710 | — |
| Novartis investigative site | Medford | Oregon | 97504 | — |
| Novartis investigative site | Providence | Rhode Island | 02908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00051636, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2012 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00051636 live on ClinicalTrials.gov.