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Terminated Phase 2 Interventional Accepts healthy volunteers

Dose Safety, Tolerability, and Immunogenicity of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination

ClinicalTrials.gov ID: NCT00053508

Public ClinicalTrials.gov record NCT00053508. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The Effect of Dose On Safety, Tolerability, and Immunogenicity of ACAM1000 Smallpox Vaccine in Adults Without Previous Smallpox Vaccination A Phase 2, Randomized, Double-Blind, Dose-Response Study

Study identification

NCT ID
NCT00053508
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Enrollment
274 participants

Conditions and interventions

Conditions

Interventions

  • ACAM1000 Biological
  • vaccinia virus (calf lymph) smallpox vaccine: Dryvax Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 29 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2002
Primary completion
Feb 28, 2003
Completion
Aug 31, 2003
Last update posted
Jan 21, 2014

2002 – 2003

United States locations

U.S. sites
3
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
Orlando Clinical Research Center Orlando Florida 32806
Mayo Vaccine Research Group Rochester Minnesota 55905
Radiant Research Cincinnati Ohio 45236

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00053508, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 21, 2014 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00053508 live on ClinicalTrials.gov.

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