Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study
Public ClinicalTrials.gov record NCT00053599. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin to Slow the Progression of Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
CLASP is a research study to investigate the safety and effectiveness of simvastatin (a cholesterol lowering drug or statin) to slow the progression of Alzheimer's disease (AD). Statins are commonly used to treat high cholesterol levels, which increase the risk of heart disease and stroke.
Study identification
- NCT ID
- NCT00053599
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 400 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2002 (Type not available)
- Primary completion
- Oct 2007 (Actual)
- Completion
- Oct 2007 (Actual)
- Last update posted
- Jul 28, 2009
2002 – 2007
United States locations
- U.S. sites
- 44
- U.S. states
- 24
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama, Birmingham | Birmingham | Alabama | 35294-0017 | — |
| Barrow Neurology Group | Phoenix | Arizona | 85013 | — |
| Arizona Health Sciences Center, University of Arizona | Tucson | Arizona | 85724-5023 | — |
| University of California, Irvine | Irvine | California | 92697-7016 | — |
| University of California, San Diego | La Jolla | California | 92093-0948 | — |
| University of Southern California | Los Angeles | California | 90093 | — |
| University of California, Los Angeles | Los Angeles | California | 90095 | — |
| Stanford University/VA Aging Clinical Research Center | Palo Alto | California | 94304 | — |
| University of California, Davis | Sacramento | California | 95817 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06511 | — |
| Georgetown University, Memory Disorder Program | Washington D.C. | District of Columbia | 20057 | — |
| Howard University | Washington D.C. | District of Columbia | 20060 | — |
| Baumel Eisner Neuromedical Institute | Boca Raton | Florida | 33486 | — |
| Mayo Clinic (Jacksonville) | Jacksonville | Florida | 32224 | — |
| Wein Center | Miami Beach | Florida | 33140 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush Alzheimer's Disease Center, Rush University | Chicago | Illinois | 60612 | — |
| Indiana University Alzheimer's Center | Indianapolis | Indiana | 46202 | — |
| University of Kentucky, Sanders-Brown Center on Aging | Lexington | Kentucky | 40536-0230 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston University School of Medicine | Boston | Massachusetts | 02118 | — |
| University of Michigan at Ann Arbor | Ann Arbor | Michigan | 48109-0504 | — |
| Mayo Clinic | Rochester | Minnesota | 55901 | — |
| St. Louis University | St Louis | Missouri | 63104 | — |
| Washington University, St. Louis School of Medicine | St Louis | Missouri | 63108 | — |
| SUNY Downstate | Brooklyn | New York | 11203 | — |
| New York University School Of Medicine | New York | New York | 10016 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| SUNY Stony Brook | Stony Brook | New York | 11794-8121 | — |
| Neurological Care of NY | Syracuse | New York | 13210 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| University Memory and Aging Center, Case Western Reserve University/University Hospitals of Cleveland | Cleveland | Ohio | 44120 | — |
| Oregon Health and Sciences University | Portland | Oregon | 97201 | — |
| University of Pennsylvania School of Medicine, Alzheimer's Disease Center | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Brown University-Memorial Hospital of Rhode Island | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | North Charleston | South Carolina | 29406 | — |
| University of Texas, Southwestern Medical School | Dallas | Texas | 75390 | — |
| Baylor College of Medicine, Alzheimer's Disease Research Center | Houston | Texas | 77030 | — |
| Southwestern Vermont Medical Center | Bennington | Vermont | 05201 | — |
| University of Washington at Seattle | Seattle | Washington | 98108 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00053599, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 28, 2009 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00053599 live on ClinicalTrials.gov.