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Completed Phase 3 Interventional

Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study

ClinicalTrials.gov ID: NCT00053599

Public ClinicalTrials.gov record NCT00053599. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 6:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin to Slow the Progression of Alzheimer's Disease

Study identification

NCT ID
NCT00053599
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
National Institute on Aging (NIA)
NIH
Enrollment
400 participants

Conditions and interventions

Interventions

  • Simvastatin Drug

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2002
Primary completion
Sep 30, 2007
Completion
Sep 30, 2007
Last update posted
Jul 27, 2009

2002 – 2007

United States locations

U.S. sites
44
U.S. states
24
U.S. cities
37
Facility City State ZIP Site status
University of Alabama, Birmingham Birmingham Alabama 35294-0017
Barrow Neurology Group Phoenix Arizona 85013
Arizona Health Sciences Center, University of Arizona Tucson Arizona 85724-5023
University of California, Irvine Irvine California 92697-7016
University of California, San Diego La Jolla California 92093-0948
University of Southern California Los Angeles California 90093
University of California, Los Angeles Los Angeles California 90095
Stanford University/VA Aging Clinical Research Center Palo Alto California 94304
University of California, Davis Sacramento California 95817
Yale University School of Medicine New Haven Connecticut 06511
Georgetown University, Memory Disorder Program Washington D.C. District of Columbia 20057
Howard University Washington D.C. District of Columbia 20060
Baumel Eisner Neuromedical Institute Boca Raton Florida 33486
Mayo Clinic (Jacksonville) Jacksonville Florida 32224
Wein Center Miami Beach Florida 33140
Emory University Atlanta Georgia 30329
Northwestern University Chicago Illinois 60611
Rush Alzheimer's Disease Center, Rush University Chicago Illinois 60612
Indiana University Alzheimer's Center Indianapolis Indiana 46202
University of Kentucky, Sanders-Brown Center on Aging Lexington Kentucky 40536-0230
Brigham and Women's Hospital Boston Massachusetts 02115
Boston University School of Medicine Boston Massachusetts 02118
University of Michigan at Ann Arbor Ann Arbor Michigan 48109-0504
Mayo Clinic Rochester Minnesota 55901
St. Louis University St Louis Missouri 63104
Washington University, St. Louis School of Medicine St Louis Missouri 63108
SUNY Downstate Brooklyn New York 11203
New York University School Of Medicine New York New York 10016
Mount Sinai School of Medicine New York New York 10029
Columbia University New York New York 10032
University of Rochester Medical Center Rochester New York 14642
SUNY Stony Brook Stony Brook New York 11794-8121
Neurological Care of NY Syracuse New York 13210
Duke University Medical Center Durham North Carolina 27705
University Memory and Aging Center, Case Western Reserve University/University Hospitals of Cleveland Cleveland Ohio 44120
Oregon Health and Sciences University Portland Oregon 97201
University of Pennsylvania School of Medicine, Alzheimer's Disease Center Philadelphia Pennsylvania 19104
University of Pittsburgh Pittsburgh Pennsylvania 15213
Brown University-Memorial Hospital of Rhode Island Providence Rhode Island 02903
Medical University of South Carolina North Charleston South Carolina 29406
University of Texas, Southwestern Medical School Dallas Texas 75390
Baylor College of Medicine, Alzheimer's Disease Research Center Houston Texas 77030
Southwestern Vermont Medical Center Bennington Vermont 05201
University of Washington at Seattle Seattle Washington 98108

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00053599, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 27, 2009 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00053599 live on ClinicalTrials.gov.

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