ClinicalTrials.gov record
Risedronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy for Primary Breast Cancer
ClinicalTrials.gov ID: NCT00054418
Public ClinicalTrials.gov record NCT00054418. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Placebo-Controlled, Double-Blind Trial Of Risedronate (Actonel) For Prevention Of Bone Loss In Premenopausal Women Undergoing Chemotherapy For Primary Breast Carcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Preventing bone loss in patients who are receiving chemotherapy for breast cancer may decrease the risk of fractures and may help patients live more comfortably. It is not yet known whether calcium is more effective with or without risedronate in preventing bone loss. PURPOSE: This randomized phase III trial is studying two forms of calcium with or without risedronate to compare how well they work in preventing bone loss in premenopausal women who are receiving chemotherapy for primary stage I, stage II, stage IIIA, or stage IIIB breast cancer.
Study identification
- NCT ID
- NCT00054418
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 216 participants
Conditions and interventions
Conditions
Interventions
- calcium carbonate Dietary Supplement
- vitamin D Dietary Supplement
- risedronate sodium Drug
- placebo Other
Dietary Supplement · Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2003
- Primary completion
- Mar 31, 2007
- Completion
- Apr 30, 2008
- Last update posted
- Jul 12, 2016
2003 – 2008
United States locations
- U.S. sites
- 198
- U.S. states
- 24
- U.S. cities
- 127
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mobile Infirmary Medical Center | Mobile | Alabama | 36652-2144 | — |
| Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259 | — |
| Aurora Presbyterian Hospital | Aurora | Colorado | 80012 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301-9019 | — |
| Penrose Cancer Center at Penrose Hospital | Colorado Springs | Colorado | 80933 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| Presbyterian - St. Luke's Medical Center | Denver | Colorado | 80218 | — |
| St. Joseph Hospital | Denver | Colorado | 80218 | — |
| Rose Medical Center | Denver | Colorado | 80220 | — |
| CCOP - Colorado Cancer Research Program, Incorporated | Denver | Colorado | 80224-2522 | — |
| Swedish Medical Center | Englewood | Colorado | 80110 | — |
| Sky Ridge Medical Center | Lone Tree | Colorado | 80124 | — |
| Hope Cancer Care Center at Longmont United Hospital | Longmont | Colorado | 80502 | — |
| St. Mary-Corwin Regional Medical Center | Pueblo | Colorado | 81004 | — |
| North Suburban Medical Center | Thorton | Colorado | 80229 | — |
| Not listed | Gainesville | Florida | 32605 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Northside Hospital Cancer Center | Atlanta | Georgia | 30342-1611 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342-1701 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342 | — |
| MBCCOP-Medical College of Georgia Cancer Center | Augusta | Georgia | 30912 | — |
| WellStar Cobb Hospital | Austell | Georgia | 30106 | — |
| Charles B. Eberhart Cancer Center at DeKalb Medical Center | Decatur | Georgia | 30033 | — |
| Gwinnett Medical Center | Lawrenceville | Georgia | 30045 | — |
| Kennestone Cancer Center at Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Southern Regional Medical Center | Riverdale | Georgia | 30274-2600 | — |
| Rush-Copley Cancer Care Center | Aurora | Illinois | 60507 | — |
| St. Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Graham Hospital | Canton | Illinois | 61520 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| Eureka Community Hospital | Eureka | Illinois | 61530 | — |
| Galesburg Clinic | Galesburg | Illinois | 61401 | — |
| Galesburg Cottage Hospital | Galesburg | Illinois | 61401 | — |
| InterCommunity Cancer Center of Western Illinois | Galesburg | Illinois | 61401 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Hopedale Medical Complex | Hopedale | Illinois | 61747 | — |
| Joliet Oncology Hematology Associates, Limited - West | Joliet | Illinois | 60435 | — |
| Kewanee Hospital | Kewanee | Illinois | 61443 | — |
| McDonough District Hospital | Macomb | Illinois | 61455 | — |
| Trinity Medical Center - East | Moline | Illinois | 61265 | — |
| Not listed | Moline | Illinois | 61265 | — |
| BroMenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Community Cancer Center | Normal | Illinois | 61761 | — |
| Community Hospital of Ottawa | Ottawa | Illinois | 61350 | — |
| Oncology Hematology Associates of Central Illinois - Ottawa | Ottawa | Illinois | 61350 | — |
| Cancer Treatment Center at Pekin Hospital | Pekin | Illinois | 61554 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61615 | — |
| Oncology/Hematology Associates of Central Illinois, P.C. | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| OSF St. Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois Valley Community Hospital | Peru | Illinois | 61354 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| St. Margaret's Hospital | Spring Valley | Illinois | 61362 | — |
| Valley Cancer Center | Spring Valley | Illinois | 61362 | — |
| Carle Cancer Center at Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Saint Anthony Memorial Health Centers | Michigan City | Indiana | 46360 | — |
| McFarland Clinic, P. C. | Ames | Iowa | 50010 | — |
| Not listed | Bettendorf | Iowa | 52722 | — |
| Saint Anthony Regional Hospital | Carroll | Iowa | 51401 | — |
| St. Luke's Hospital | Cedar Rapids | Iowa | 52402 | — |
| Cedar Rapids Oncology Associates | Cedar Rapids | Iowa | 52403 | — |
| Mercy Regional Cancer Center at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Alegent Health Mercy Hospital | Council Bluffs | Iowa | 51503 | — |
| Mercy Capitol Hospital | Des Moines | Iowa | 50307 | — |
| CCOP - Iowa Oncology Research Association | Des Moines | Iowa | 50309 | — |
| John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates at John Stoddard Cancer Center | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates at Mercy Cancer Center | Des Moines | Iowa | 50314 | — |
| Mercy Cancer Center at Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| John Stoddard Cancer Center at Iowa Lutheran Hospital | Des Moines | Iowa | 50316-2301 | — |
| Alegent Health Community Memorial Hospital | Missouri Valley | Iowa | 51555-1199 | — |
| Burgess Health Center | Onawa | Iowa | 51040 | — |
| Ottumwa Regional Health Center Cancer Center | Ottumwa | Iowa | 52501 | — |
| Siouxland Hematology-Oncology Associates at June E. Nylen Cancer Center | Sioux City | Iowa | 51101 | — |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | — |
| Mercy Medical Center - Sioux City | Sioux City | Iowa | 51104 | — |
| St. Luke's Regional Medical Center | Sioux City | Iowa | 51104 | — |
| Medical Oncology and Hematology Associates - West Des Moines | West Des Moines | Iowa | 50266 | — |
| Cancer Center of Kansas, P.A. - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas, P.A. - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas, P.A. - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas, P.A. - Kingman | Kingman | Kansas | 67068 | — |
| Southwest Medical Center | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas, P.A. - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas, P.A. - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas, P.A. - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas, P.A. - Salina | Salina | Kansas | 67042 | — |
| Cancer Center of Kansas, P.A. - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Womens Health, P.A. - North Review | Wichita | Kansas | 67203 | — |
| Cancer Center of Kansas, P.A. - Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, P.A. - Wichita | Wichita | Kansas | 67214 | — |
| CCOP - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas, P.A. - Winfield | Winfield | Kansas | 67156 | — |
| Ochsner Clinic of Baton Rouge | Baton Rouge | Louisiana | 708169990 | — |
| Terrebonne General Medical Center | Houma | Louisiana | 70360 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Hickman Cancer Center at Bixby Medical Center | Adrian | Michigan | 49221 | — |
| St. Joseph Mercy Cancer Center at St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| Green Bay Oncology, Limited - Escanaba | Escanaba | Michigan | 49431 | — |
| Green Bay Oncology, Limited - Iron Mountain | Iron Mountain | Michigan | 49801 | — |
| Haematology-Oncology Associates of Ohio and Michigan, P.C. | Lambertville | Michigan | 48144 | — |
| Community Cancer Center of Monroe | Monroe | Michigan | 48162 | — |
| Mercy Memorial Hospital System | Monroe | Michigan | 48162 | — |
| MeritCare Clinic - Bemidji | Bemidji | Minnesota | 56601 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| Miller-Dwan Medical Center | Duluth | Minnesota | 55805 | — |
| St. Mary's - Duluth Clinic Cancer Center | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Mercy and Unity Cancer Center at Unity Hospital | Fridley | Minnesota | 55432 | — |
| Immanuel St. Joseph's Clinic | Mankato | Minnesota | 56002 | — |
| Virginia Piper Cancer Institute at Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hubert H. Humphrey Cancer Center at North Memorial Medical Center | Robbinsdale | Minnesota | 55422-2900 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Health Services | Saint Louis Park | Minnesota | 55416 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Hattiesburg Clinic, P.A. | Hattiesburg | Mississippi | 39401 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| St. Vincent Healthcare | Billings | Montana | 59101 | — |
| Deaconess Billings Clinic Cancer Center | Billings | Montana | 59107-5100 | — |
| Deaconess Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Internal Medicine Associates of Bozeman | Bozeman | Montana | 59715 | — |
| St. James Community Hospital | Butte | Montana | 59701 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| St. Peter's Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology, PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology | Kalispell | Montana | 59901 | — |
| Eastern Montana Cancer Center | Miles City | Montana | 59301 | — |
| Community Medical Center | Missoula | Montana | 59801 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59807-7877 | — |
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | 59807 | — |
| Bryan LGH Medical Center West | Lincoln | Nebraska | 68502 | — |
| Cancer Resource Center - Lincoln | Lincoln | Nebraska | 68510 | — |
| St. Elizabeth Regional Medical Center | Lincoln | Nebraska | 68510 | — |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68106 | — |
| Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Creighton University Medical Center | Omaha | Nebraska | 68131-2197 | — |
| Midlands Cancer Center at Midlands Community Hospital | Papillion | Nebraska | 68046-4194 | — |
| Rutherford Hospital | Rutherfordton | North Carolina | 28139 | — |
| Bismarck Cancer Center | Bismarck | North Dakota | 58501 | — |
| Cancer Care Center at Medcenter One Hospital | Bismarck | North Dakota | 58501 | — |
| Mid Dakota Clinic, P. C. | Bismarck | North Dakota | 58501 | — |
| St. Alexius Medical Center | Bismarck | North Dakota | 58502 | — |
| CCOP - MeritCare Hospital | Fargo | North Dakota | 58122 | — |
| MeritCare Medical Group | Fargo | North Dakota | 58122 | — |
| Altru Cancer Center at Altru Hospital | Grand Forks | North Dakota | 58201 | — |
| Wood County Oncology Center | Bowling Green | Ohio | 43402 | — |
| Blanchard Valley Medical Associates | Findlay | Ohio | 45840 | — |
| Fremont Memorial Hospital | Fremont | Ohio | 43420 | — |
| Kenton Oncology, Incorporated | Kenton | Ohio | 43326 | — |
| Lima Memorial Hospital | Lima | Ohio | 45804 | — |
| Northwest Ohio Oncology Center | Maumee | Ohio | 43537 | — |
| St. Luke's Hospital | Maumee | Ohio | 43537 | — |
| St. Charles Mercy Hospital | Oregon | Ohio | 43616 | — |
| Toledo Clinic - Oregon | Oregon | Ohio | 43616 | — |
| Firelands Regional Medical Center | Sandusky | Ohio | 44870 | — |
| North Coast Cancer Care, Incorporated | Sandusky | Ohio | 44870 | — |
| Promedica Cancer Center at Flower Hospital | Sylvania | Ohio | 43560 | — |
| Mercy Hospital of Tiffin | Tiffin | Ohio | 44883 | — |
| Toledo Hospital | Toledo | Ohio | 43606 | — |
| St. Vincent Mercy Medical Center | Toledo | Ohio | 43608 | — |
| Medical College of Ohio Cancer Institute | Toledo | Ohio | 43614 | — |
| CCOP - Toledo Community Hospital | Toledo | Ohio | 43623 | — |
| Toledo Clinic, Incorporated - Main Clinic | Toledo | Ohio | 43623 | — |
| Toledo Surgical Specialists | Toledo | Ohio | 43623 | — |
| Fulton County Health Center | Wauseon | Ohio | 43567 | — |
| Natalie Warren Bryant Cancer Center at St. Francis Hospital | Tulsa | Oklahoma | 74136 | — |
| Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest | Allentown | Pennsylvania | 18105 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-0001 | — |
| Geisinger Medical Group | State College | Pennsylvania | 16801 | — |
| Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| Rose Ramer Cancer Clinic at Anderson Area Medical Center | Anderson | South Carolina | 29621 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| Gibbs Regional Cancer Center at Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Avera McKennan Hospital and University Health Center | Sioux Falls | South Dakota | 57105-1080 | — |
| Medical X-Ray Center, P. C. | Sioux Falls | South Dakota | 57105 | — |
| Sioux Valley Hospital and University of South Dakota Medical Center | Sioux Falls | South Dakota | 57117-5039 | — |
| Green Bay Oncology, Limited at St. Vincent Hospital | Green Bay | Wisconsin | 54301-3526 | — |
| Green Bay Oncology, Limited at St. Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| St. Mary's Hospital Medical Center - Green Bay | Green Bay | Wisconsin | 54303 | — |
| St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54307-3508 | — |
| Green Bay Oncology, Limited - Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Green Bay Oncology, Limited - Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235 | — |
| Welch Cancer Center at Sheridan Memorial Hospital | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00054418, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 12, 2016 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00054418 live on ClinicalTrials.gov.