A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and Effectiveness in Preventing Post-Angioplasty Blood Vessel Re-Closure (Restenosis) in Stented Vessels.
Public ClinicalTrials.gov record NCT00055510. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This research study is intended to evaluate the safety and effectiveness of 3 different doses of BO-653, an investigational inhibitor of LDL cholesterol oxidation, when given orally twice a day compared to placebo (an inactive substance) in preventing restenosis (closure of vessel) within six months after stent implantation. Patients must be enrolled into this study within 24 hours after the stenting procedure. Additionally, over a 1- to 9-month post-stent period, the study will compare the safety and effectiveness of BO-653 versus placebo for measures of coronary artery vessel size by quantitative coronary angiography, major adverse cardiac events, and effects on the oxidative status of plasma lipids and other plasma components.
Study identification
- NCT ID
- NCT00055510
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- Not listed
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 24, 2005
United States locations
- U.S. sites
- 29
- U.S. states
- 17
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Luke's Medical Center | Phoenix | Arizona | 85006 | — |
| University of Arizona Sarver Heart Center | Tucson | Arizona | 85724 | — |
| Cardiovascular Associates of the Peninsula | Burlingame | California | 94010 | — |
| Foundation for Cardiovascular Medicine | La Jolla | California | 92037 | — |
| La Mesa Cardiac Center | La Mesa | California | 91942 | — |
| Clinical Research Center of California | San Diego | California | 92117 | — |
| Veterans Affairs Medical Center | San Diego | California | 92161 | — |
| University of Florida Health Science Center | Jacksonville | Florida | 32209 | — |
| Miami International Cardiology Consultants | Miami Beach | Florida | 33140 | — |
| Mediquest Research Group | Ocala | Florida | 34474 | — |
| Midwest Heart Research Foundation | Lombard | Illinois | 60148 | — |
| Iowa Heart Center | Des Moines | Iowa | 50314 | — |
| Alton Ochsner Medical Foundation | New Orleans | Louisiana | 70121 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | — |
| Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| St. Louis University | St Louis | Missouri | 63110 | — |
| Nevada Cardiology Associates | Las Vegas | Nevada | 89109 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Asheville Cardiology Associates, PA | Asheville | North Carolina | 28803 | — |
| Northwestern Memorial Hospital | Elyria | Ohio | 44035 | — |
| Oklahoma Foundation for Cardiovascular Research | Oklahoma City | Oklahoma | 73120 | — |
| Austin Heart | Austin | Texas | 78756 | — |
| IRCI Institute for Research in Cardiovascular Interventions at The Methodist DeBakey Heart Center | Houston | Texas | 77030 | — |
| University of Texas Health Science Center | San Antonio | Texas | 78229-3900 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00055510, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00055510 live on ClinicalTrials.gov.