VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)
Public ClinicalTrials.gov record NCT00056225. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
High Dose Supplements to Reduce Homocysteine and Slow the Rate of Cognitive Decline in Alzheimer's Disease (Vitamins to Slow Alzheimer's - VITAL)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether reduction of homocysteine levels with high-dose folate (folic acid), B6, and B12 supplementation will slow the rate of cognitive decline in persons with Alzheimer's disease.
Study identification
- NCT ID
- NCT00056225
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 340 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2003 (Type not available)
- Primary completion
- Jun 2007 (Actual)
- Completion
- Jun 2007 (Actual)
- Last update posted
- Jun 12, 2009
2003 – 2007
United States locations
- U.S. sites
- 38
- U.S. states
- 21
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| Mayo Clinic, Scottsdale | Scottsdale | Arizona | 85259 | — |
| Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| University of Arizona, Arizona Health Sciences Center | Tucson | Arizona | 85724 | — |
| University of California, Irvine, Institute for Brain Aging and Dementia | Irvine | California | 92697 | — |
| University of California, San Diego | La Jolla | California | 92093-0624 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California, Los Angeles | Los Angeles | California | 90095 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| University of California, Davis | Sacramento | California | 95817 | — |
| Yale University | New Haven | Connecticut | 06510 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20057 | — |
| Howard University | Washington D.C. | District of Columbia | 20060 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| University of South Florida | Tampa | Florida | 33617 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush Presbyterian/St. Lukes Medical Center, Rush Alzheimer's Disease Center | Chicago | Illinois | 60612 | — |
| Southern Illinois University | Springfield | Illinois | 62794-9643 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston University School of Medicine | Boston | Massachusetts | 02118 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| University of Nevada School of Medicine, Center for Cognitive Aging | Las Vegas | Nevada | 89102 | — |
| ClinSearch | Kenilworth | New Jersey | 07033 | — |
| New York University Medical Center | New York | New York | 10016 | — |
| Mt. Sinai School of Medicine | New York | New York | 10029 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Rochester Medical Center, Alzheimer's Disease Center | Rochester | New York | 14620 | — |
| University Memory and Aging Center, Case Western Reserve University/University Hospitals of Cleveland | Cleveland | Ohio | 44120 | — |
| Oregon Health and Science University, Oregon Aging and Alzheimer's Disease Center | Portland | Oregon | 97201 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Memorial Hospital of Rhode Island, Alzheimer's Disease and Memory Disorder Clinic | Pawtucket | Rhode Island | 02860 | — |
| Medical University of South Carolina | North Charleston | South Carolina | 29406 | — |
| University of Texas, Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Washington | Seattle | Washington | 98108 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00056225, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 12, 2009 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00056225 live on ClinicalTrials.gov.