ClinicalTrials.gov record
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer
ClinicalTrials.gov ID: NCT00056446
Public ClinicalTrials.gov record NCT00056446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Phase III Study of Oxaliplatin/5-fluorouracil/Leucovorin With PTK787/ZK 222584 or Placebo in Patients With Previously Treated Metastatic Adenocarcinoma of the Colon or Rectum
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal cancer that has spread to other organs and whose disease has worsened after treatment with irinotecan.
Study identification
- NCT ID
- NCT00056446
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 855 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2003 (Type not available)
- Primary completion
- Jan 2007 (Actual)
- Completion
- Jan 2007 (Actual)
- Last update posted
- Mar 6, 2017
2003 – 2007
United States locations
- U.S. sites
- 143
- U.S. states
- 41
- U.S. cities
- 116
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Cancer Institute | Huntsville | Alabama | 35801 | — |
| Alaska Oncology and Hematology | Anchorage | Alaska | 99508 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85712 | — |
| Northeast Arkansas Clinic | Jonesboro | Arkansas | 72401 | — |
| Arkansas Cancer Research Center | Little Rock | Arkansas | 72205 | — |
| Little Rock Hematology & Oncology | Little Rock | Arkansas | 72205 | — |
| Highlands Oncology Group | Springdale | Arkansas | 72764 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Providence St. Joseph Medical Center | Burbank | California | 91505 | — |
| Compassionate Cancer Care Medical Group, Inc. | Fountain Valley | California | 92708 | — |
| California Oncology of the Central Valley | Fresno | California | 93710 | — |
| Virginia K. Crosson Cancer Center | Fullerton | California | 92835 | — |
| Glendale Adventist Medical Center | Glendale | California | 91206 | — |
| Scripps Green Hospital | La Jolla | California | 92037 | — |
| Wilshire Oncology Medical Group | La Verne | California | 91767 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| USC Norris Cancer Center | Los Angeles | California | 90033 | — |
| Synergy Hematology-Oncology Medical Associates | Los Angeles | California | 90036 | — |
| Novartis Investigative Site | Los Angeles | California | 90095 | — |
| UCLA School of Medicine | Los Angeles | California | 90095 | — |
| Eddie Hong-Lung Hu, M.D. | Monterey Park | California | 91754 | — |
| North Valley Hematology/Oncology Medical Group | Northridge | California | 91328 | — |
| Medical Oncology Care Associates | Orange | California | 92868 | — |
| Ventura County Hematology-Oncology Specialists | Oxnard | California | 93030 | — |
| Sierra View District Hospital | Porterville | California | 93257 | — |
| Cancer Care Associates Medical Group, Inc. | Redondo Beach | California | 90277 | — |
| Santa Clara Valley Medical Center | San Jose | California | 95128 | — |
| Sansum Santa Barbara Foundation Medical Clinic | Santa Barbara | California | 93105 | — |
| Santa Barbara Hematology Oncology Medical Group, Inc. | Santa Barbara | California | 93105 | — |
| San Diego Cancer Center Medical Group | Vista | California | 92083 | — |
| Mile High Oncology | Denver | Colorado | 80210 | — |
| Rocky Mountain Cancer Center | Denver | Colorado | 80220 | — |
| Manchester Hematology/Oncology Assoc. | Manchester | Connecticut | 06040 | — |
| Washington Oncology/Hematology Center | Washington D.C. | District of Columbia | 20037 | — |
| The Center for Hematology and Oncology | Boca Raton | Florida | 33486 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33901 | — |
| Hematology Oncology Associates | Lake Worth | Florida | 33461-4710 | — |
| University of Miami School of Medicine | Miami | Florida | 33136 | — |
| Oncology/Hematology Group of South Florida | Miami | Florida | 33176 | — |
| Hematology Oncology Associates of Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Florida Medical Clinic | Zephyrhills | Florida | 33542 | — |
| Atlanta Cancer Care | Marietta | Georgia | 30060 | — |
| Office of Research | Savannah | Georgia | 31405 | — |
| Coastal Hematology & Oncology | Savannah | Georgia | 31406 | — |
| Lewis Hall Singletary Oncology Center | Thomasville | Georgia | 31792 | — |
| North Idaho Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| University of Chicago medical Center, Hematology/Oncology | Chicago | Illinois | 60637 | — |
| Oncology Hematology Associates of Central Illinois, PC | Peoria | Illinois | 61602 | — |
| Northshore Cancer Research Association | Skokie | Illinois | 60076 | — |
| Midwest Cancer Research Group | Skokie | Illinois | 60077 | — |
| Fort Wayne Medical Oncology & Hematology, Inc. | Fort Wayne | Indiana | 46815 | — |
| Munster Community Hospital | Munster | Indiana | 46321 | — |
| Cotton O'Neil Oncology Clinic | Topeka | Kansas | 66606 | — |
| Vijay Raghaven, M.D. | Louisville | Kentucky | 40215 | — |
| Owensboro Medical Health System | Owensboro | Kentucky | 42303 | — |
| Cabrini Center for Cancer Care | Alexandria | Louisiana | 71301 | — |
| LSU Medical Center | New Orleans | Louisiana | 70112 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| LSU Health Sciences Center | Shreveport | Louisiana | 71130-3932 | — |
| Maine Center for Cancer Medicine & Blood Disorders | Scarborough | Maine | 04074 | — |
| St. Agnes Healthcare | Baltimore | Maryland | 21229-5299 | — |
| Franklin Square Hospital Center | Baltimore | Maryland | 21237 | — |
| Kaiser Permanente | Rockville | Maryland | 20850 | — |
| Fallon Clinic at Worcester Medical Center | Worcester | Massachusetts | 01605 | — |
| University of Michigan | Ann Arbor | Michigan | 48109-0934 | — |
| Spectrum Health -- Cook Research Dept. | Grand Rapids | Michigan | 49503 | — |
| Oncology Care Associates, PLLC | Saint Joseph | Michigan | 49085 | — |
| Providence Cancer Center | Southfield | Michigan | 48075 | — |
| Minnesota CGOP | Minneapolis | Minnesota | 55407 | — |
| Heartland Hematology | Kansas City | Missouri | 64118 | — |
| Missouri Cancer Care, PC | Saint Charles | Missouri | 63301 | — |
| Saint Louis University | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| Arch Medical Services Incorporated | St Louis | Missouri | 63141 | — |
| North Central Montana Professional Building | Great Falls | Montana | 59405 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89109 | — |
| Nevada Cancer Center | Las Vegas | Nevada | 89109 | — |
| NH Oncology-Hematology, PA | Hooksett | New Hampshire | 03106 | — |
| Center for Cancer and Hematologic Disease | Cherry Hill | New Jersey | 08003 | — |
| St. Barnabas Cancer Center | Livingston | New Jersey | 07039 | — |
| Hematology Oncology Associates of Northern New Jersey | Morristown | New Jersey | 07960 | — |
| Cooper Cancer Center | Voorhees Township | New Jersey | 08043 | — |
| Hematology/Oncology Associates | Albuquerque | New Mexico | 87102 | — |
| New Mexico Oncology/Hematology | Albuquerque | New Mexico | 87109 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Hematology/Oncology Associates of Central NY | East Syracuse | New York | 13057 | — |
| Queens Medical Associates, PC | Fresh Meadows | New York | 11365 | — |
| Charles R. Wood Cancer Center | Glens Falls | New York | 12801 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| St. Vincent's Catholic Medical Centers of New York | New York | New York | 10011 | — |
| Hematology-Oncology Associates of Rockland | Nyack | New York | 10956 | — |
| Pluta Cancer Center | Rochester | New York | 14623 | — |
| James P. Wilmot Cancer Center | Rochester | New York | 14642 | — |
| Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599-7305 | — |
| Carolinas Hematology/Oncology Associates | Charlotte | North Carolina | 28203 | — |
| Nashat Gabrail, M.D. | Canton | Ohio | 44718 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106-5056 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Columbus CCOP | Columbus | Ohio | 43206 | — |
| The University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Oklahoma Oncology, Inc. | Tulsa | Oklahoma | 74104 | — |
| Consultants in Medical Oncology & Hematology | Drexel Hill | Pennsylvania | 19026 | — |
| Hematology & Oncology Associates of NE PA | Dunmore | Pennsylvania | 18512 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Monongahela Valley Hospital | Monongahela | Pennsylvania | 15063 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212-4772 | — |
| UPMC Cancer Pavillion | Pittsburgh | Pennsylvania | 15232 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| South Carolina Oncology Associates | Columbia | South Carolina | 29201 | — |
| WJB Dom VAMC | Columbia | South Carolina | 29209 | — |
| Cancer Center of the Carolinas | Greenville | South Carolina | 29615 | — |
| Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Erlanger Health System | Chattanooga | Tennessee | 37403 | — |
| Clarksville Regional Hematology/Oncology | Clarksville | Tennessee | 37043 | — |
| The Jones Clinic | Germantown | Tennessee | 38138 | — |
| Baptist Regional Cancer Center | Knoxville | Tennessee | 37920 | — |
| University of Tennessee Cancer Institute | Memphis | Tennessee | 38104 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | — |
| Meharry Medical College | Nashville | Tennessee | 37208 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37212 | — |
| Vanderbilt University School of Medicine | Nashville | Tennessee | 37232-6307 | — |
| Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| Center for Oncology Research & Treatment | Dallas | Texas | 75230 | — |
| Clinical Hematology & Oncology | Dallas | Texas | 75235 | — |
| Oncology Consultants | Houston | Texas | 77024 | — |
| H. Alejandro Preti, M.D., PA | Houston | Texas | 77030 | — |
| M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| South Texas Oncology & Hematology | San Antonio | Texas | 78207 | — |
| Scott & White Hospital | Temple | Texas | 76508 | — |
| Northern Utah Cancer Associates | Ogden | Utah | 84403 | — |
| Southwestern Vermont Health Care | Bennington | Vermont | 05201 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Cancer Treatment Centers of America in Hampton Roads | Portsmouth | Virginia | 23704 | — |
| Western Washington Clinic | Everett | Washington | 98201 | — |
| Cascade Cancer Center | Kirkland | Washington | 98034 | — |
| Rainier Oncology | Puyallup | Washington | 98372 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| West Virginia University Health Sciences Center | Morgantown | West Virginia | 26506 | — |
| Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
| Kettle Morain Oncology | West Bend | Wisconsin | 53095 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 108 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00056446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 6, 2017 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00056446 live on ClinicalTrials.gov.