ClinicalTrials.gov record
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.
ClinicalTrials.gov ID: NCT00056459
Public ClinicalTrials.gov record NCT00056459. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Phase Lll Study in Patients With Metastatic Adenocarcinoma of the Colon or Rectum Who Are Receiving First-line Chemotherapy With Oxaliplatin/5-fluorouracil/Leucovorin With PTK787/ZK 222584 or Placebo
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal cancer that has spread to other organs and are seeking first chemotherapy treatment
Study identification
- NCT ID
- NCT00056459
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,168 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2003 (Type not available)
- Primary completion
- Jan 2007 (Actual)
- Completion
- Not listed
- Last update posted
- Feb 10, 2020
Started 2003
United States locations
- U.S. sites
- 145
- U.S. states
- 40
- U.S. cities
- 126
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Hematology/Oncology | Birmingham | Alabama | 35243 | — |
| Palo Verde Hematology & Oncology | Glendale | Arizona | 85304 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| Northeast Arkansas Clinic | Jonesboro | Arkansas | 72401 | — |
| Highlands Oncology Group | Springdale | Arkansas | 72764 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Providence St. Joseph Medical Center | Burbank | California | 91505 | — |
| Compassionate Cancer Care Medical Group, Inc | Fountain Valley | California | 92708 | — |
| California Oncology of the Central Valley | Fresno | California | 93710 | — |
| Virginia K. Crosson Cancer Center | Fullerton | California | 92835 | — |
| Ronald Yanagiharaa, M.D. | Gilroy | California | 95020 | — |
| Glendale Adventist Medical Center Cancer Center | Glendale | California | 91206 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| Cancer Institute Medical Group | Los Angeles | California | 90025 | — |
| USC/Norris Comprehensive Cancer Care Center | Los Angeles | California | 90033 | — |
| Synergy Hematology-Oncology Medical Associates | Los Angeles | California | 90057 | — |
| UCLA School of Medicine | Los Angeles | California | 90095 | — |
| Eddie Hong-Lung Hu, M.D. | Monterey Park | California | 91754 | — |
| North Valley Hematology/Oncology Medical Group | Northridge | California | 91328 | — |
| Ventura County Hematology-Oncology Specialists | Oxnard | California | 93030 | — |
| Wilshire Oncology Medical Group | Pomona | California | 91767 | — |
| Sierra View District Hospital | Porterville | California | 93257 | — |
| The Lucy Curci Cancer Center | Rancho Mirage | California | 92270 | — |
| Cancer Care Associates Medical Group, Inc. | Redondo Beach | California | 90277 | — |
| Pacific Hematology Oncology Associates | San Francisco | California | 94904 | — |
| Santa Clara Valley Medical Center | San Jose | California | 95128 | — |
| Sansum Santa Barbara Foundation Medical Clinic | Santa Barbara | California | 93105 | — |
| Santa Barbara Hematology Oncology Medical Group, Inc. | Santa Barbara | California | 93105 | — |
| San Diego Cancer Center Medical Group | Vista | California | 92083 | — |
| Colorado Cancer Research Program | Denver | Colorado | 80224 | — |
| Jennifer Caskey, M.D. | Wheat Ridge | Colorado | 08833 | — |
| Davis, Posteraro and Wasser, MD's, LLP | Manchester | Connecticut | 06040 | — |
| Connecticut Oncology Group | Middletown | Connecticut | 06457 | — |
| Medical Oncology Hematology Consultants | Newark | Delaware | 19808 | — |
| Washington Oncology-Hematology Center | Washington D.C. | District of Columbia | 20016 | — |
| George Washington University Medical Center | Washington D.C. | District of Columbia | 20037 | — |
| Boca Raton Comprehensive Cancer Center | Boca Raton | Florida | 33486 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33901 | — |
| Memorial Healthcare System | Hollywood | Florida | 33021 | — |
| Florida Oncology Associates | Jacksonville | Florida | 32204 | — |
| Lakeland Regional Cancer Center | Lakeland | Florida | 33803 | — |
| Oncology Hematology Group of South Florida | Miami | Florida | 33176 | — |
| Innovative Medical Research of South Florida | Miami Shores | Florida | 33138 | — |
| Hematology Oncology Associates of Treasure | Port Saint Lucie | Florida | 34952 | — |
| Florida Medical Clinic, PA | Zephyrhills | Florida | 33542 | — |
| Peachtree Hematology and Oncology | Atlanta | Georgia | 40202 | — |
| Coastal Hematology & Oncology | Savannah | Georgia | 31406 | — |
| North Idaho Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| Shelby D. Rifkin, M.D. | Arlington Heights | Illinois | 60004 | — |
| Monroe Medical Associates | Harvey | Illinois | 60426 | — |
| Oncology Hematology Associates of Central Illinois, PC | Peoria | Illinois | 61602 | — |
| Northshore Cancer Research Association | Skokie | Illinois | 60076 | — |
| Midwest Cancer Research Group | Skokie | Illinois | 60077 | — |
| Hematology-Oncology of Indiana, PC | Indianapolis | Indiana | 46260 | — |
| Associated Physicians & Surgeons Clinic, L.L.C. | Terre Haute | Indiana | 47804 | — |
| Markey Clinical Oncology Research Program | Lexington | Kentucky | 40536-0098 | — |
| Norton Healthcare Pavilion | Louisville | Kentucky | 40202 | — |
| Vijay Raghavan, M.D. | Louisville | Kentucky | 40215 | — |
| Louisiana Oncology Associates | Lafayette | Louisiana | 70506 | — |
| LSU Medical Center | New Orleans | Louisiana | 70112 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| LSU Health Sciences Center | Shreveport | Louisiana | 71130-3932 | — |
| Maine Center for Cancer Medicine & Blood Disorders | Scarborough | Maine | 04074 | — |
| St. Agnes Healthcare, Inc. | Baltimore | Maryland | 21229-5299 | — |
| Kaiser Permanente | Rockville | Maryland | 20850 | — |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| Josephine Ford Cancer Center | Detroit | Michigan | 48202 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Spectrum Health -- Cook Research Dept. | Grand Rapids | Michigan | 49503 | — |
| Hematology and Oncology Assoc. of Southern Mississippi | Jackson | Michigan | 48201 | — |
| Oncology Care Associates, PLLC | Saint Joseph | Michigan | 49085 | — |
| Providence Cancer Center | Southfield | Michigan | 48075 | — |
| SMDC Health System | Duluth | Minnesota | 55805 | — |
| Minnesota CGOP | Minneapolis | Minnesota | 55407 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Metro Minnesota CCOP | Saint Louis Park | Minnesota | 55426 | — |
| Heartland Hematology/Oncology Associates, Inc. | Kansas City | Missouri | 64118 | — |
| Kansas City Oncology and Hematology Group | Kansas City | Missouri | 64131 | — |
| Missouri Cancer Care, PC | Saint Charles | Missouri | 63301 | — |
| Saint Louis University | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| Arch Medical Services Incorporated | St Louis | Missouri | 63141 | — |
| North Central Montana Professional Building | Great Falls | Montana | 59405 | — |
| Montana Cancer Specialists | Missoula | Montana | 59807-7877 | — |
| The Methodist Cancer Center | Omaha | Nebraska | 68114 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89109 | — |
| Nevada Cancer Center | Las Vegas | Nevada | 89109 | — |
| The Center for Cancer and Hematologic Disease | Cherry Hill | New Jersey | 08003 | — |
| St. Barnabas Cancer Center | Livingston | New Jersey | 07039 | — |
| Hematology-Oncology Associates of New Jersey | Morristown | New Jersey | 07960 | — |
| Southern Oncology and Hematology Associates | Vineland | New Jersey | 08360 | — |
| Cooper Cancer Institute | Voorhees Township | New Jersey | 08043 | — |
| New Mexico Cancer Care | Santa Fe | New Mexico | 87505 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| CR Wood Cancer Center | Glens Falls | New York | 12801 | — |
| Cancer Research of Long Island | Great Neck | New York | 11023 | — |
| Broome Oncology | Johnson City | New York | 13790 | — |
| New York Oncology Hematology | Latham | New York | 12110 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Cancer Center at Nyack Hospital | Nyack | New York | 10960 | — |
| Pluta Cancer Center | Rochester | New York | 14623 | — |
| Carolina Medical Center | Charlotte | North Carolina | 28203 | — |
| Mid-Dakota Clinic PC | Bismarck | North Dakota | 58501 | — |
| Nashat Gabrail, M.D. | Canton | Ohio | 44718 | — |
| Mid Ohio Oncology/Hematology, Inc. | Columbus | Ohio | 43213 | — |
| Hematology Oncology Consultants, Inc. | Columbus | Ohio | 43235 | — |
| Meridia Cancer Institute | Mayfield Heights | Ohio | 44124 | — |
| Cancer Care Associates | Oklahoma City | Oklahoma | 73112 | — |
| Cancer Care Associates | Tulsa | Oklahoma | 74136-1929 | — |
| Kaiser Permanente Oncology Hematology | Portland | Oregon | 97227 | — |
| Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Monogahela Valley Hospital | Monongahela | Pennsylvania | 15063 | — |
| University of Pennsylvania Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny Cancer Center | Pittsburgh | Pennsylvania | 15212-4772 | — |
| Charleston Hematology Oncology | Charleston | South Carolina | 29403 | — |
| Charleston Cancer Center | Charleston | South Carolina | 29406 | — |
| South Carolina Oncology Associates | Columbia | South Carolina | 29201 | — |
| Cancer Center of the Carolinas | Greenville | South Carolina | 29615 | — |
| Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| The Jones Clinic | Germantown | Tennessee | 38138 | — |
| Baptist Regional Cancer Center | Knoxville | Tennessee | 37920 | — |
| University of Tennessee Cancer Institute | Memphis | Tennessee | 38104 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | — |
| Southwest Regional Cancer Center | Austin | Texas | 78705 | — |
| Corpus Christi Cancer Center | Corpus Christi | Texas | 78412 | — |
| Center for Oncology Research & Treatment, PA | Dallas | Texas | 75230 | — |
| Oncology Consultants | Houston | Texas | 77024 | — |
| H. Alejandro Preti, MD, PA | Houston | Texas | 77030 | — |
| M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| Dr. Lee C. Drinkard | Irving | Texas | 75038 | — |
| Scott & White Hospital | Temple | Texas | 76508 | — |
| North Utah Associates | Ogden | Utah | 84403-3105 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84124 | — |
| Southwestern Vermont Health Care | Bennington | Vermont | 05201 | — |
| Danville Hematology and Oncology, Inc. | Danville | Virginia | 24541 | — |
| Northern Virginia Oncology Group | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Cancer Treatment Centers of America | Portsmouth | Virginia | 23704 | — |
| Virginia Cancer Institute | Richmond | Virginia | 23230 | — |
| Western Washington Medical Group | Everett | Washington | 98201 | — |
| Western Washington Medical Group | Everett | Washington | 982901 | — |
| Cascade Cancer Center | Kirkland | Washington | 98034 | — |
| UW Health -- University of Wisconsin Comp | Madison | Wisconsin | 53792 | — |
| Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 78 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00056459, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 10, 2020 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00056459 live on ClinicalTrials.gov.