Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)
Public ClinicalTrials.gov record NCT00056524. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Multicenter Study to Assess the Safety of AVP-923 in the Treatment of Patients With Pseudobulbar Affect.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the long-term safety of AVP-923 in the treatment of Involuntary Emotional Expression Disorder (IEED) also known as Pseudobulbar Affect (episodes of uncontrolled crying and/or laughter).
Study identification
- NCT ID
- NCT00056524
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 600 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2003 (Type not available)
- Primary completion
- Jun 2007 (Actual)
- Completion
- Jun 2007 (Actual)
- Last update posted
- Jul 14, 2016
2003 – 2007
United States locations
- U.S. sites
- 39
- U.S. states
- 18
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Center for Neurologic Study | La Jolla | California | 92037 | — |
| UCLA School of Medicine | Los Angeles | California | 90095 | — |
| UCSF | San Francisco | California | 94117 | — |
| Research Center for Clinical Studies, Inc. | Darien | Connecticut | 06820 | — |
| George Washington University Medical Faculty Assoc. | Washington D.C. | District of Columbia | 20037 | — |
| Neurological Associates | Fort Lauderdale | Florida | 33334 | — |
| University of Miami Dept. of Neurology | Miami | Florida | 33136 | — |
| Miami Jewish Home & Hospital for the Aged | Miami | Florida | 33137 | — |
| Allied Clinical Trials | Miami | Florida | 33181 | — |
| Renstar Medical Research | Plantation | Florida | 33324 | — |
| Suncoast Neuroscience Associates Inc. | St. Petersburg | Florida | 33701 | — |
| Not listed | Tampa | Florida | 33606 | — |
| Neurology & Headache Specialist of Atlanta, L.L.C. | Decatur | Georgia | 30033 | — |
| Consultants in Neurology LTD | Northbrook | Illinois | 60062 | — |
| Advanced Neurology Specialists | Great Falls | Montana | 59405 | — |
| Neurological Associates, P.C. | Lincoln | Nebraska | 68506 | — |
| Upstate Clinical Research | Albany | New York | 12205 | — |
| DENT Neurologic Group L.L.P. | Amherst | New York | 14266 | — |
| Hospital for Joint Diseases MS Care Center | New York | New York | 10003 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Raleigh Neurology Associates, PA | Raleigh | North Carolina | 27607 | — |
| NeuroCare Center, Inc. | Canton | Ohio | 44718 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| University Memory and Aging Center | Cleveland | Ohio | 44120 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Clinical Pharmaceutical Trials, Inc. | Tulsa | Oklahoma | 74104 | — |
| Lehigh Valley Neurosciences and Pain Research Center | Allentown | Pennsylvania | 18103 | — |
| Westmoreland Neurology | Greensburg | Pennsylvania | 15601 | — |
| Not listed | Jenkintown | Pennsylvania | 19046 | — |
| MCP-Hahnemann University | Philadelphia | Pennsylvania | 19107 | — |
| Penn Neurological Institute | Philadelphia | Pennsylvania | 19107 | — |
| Neurological Associates of Delaware Valley | Upland | Pennsylvania | 19013 | — |
| Claghorn-Lesem Research Clinic | Bellaire | Texas | 77401 | — |
| Methodist Neurological Institute | Houston | Texas | 77030 | — |
| Fletcher Allen Health Care | Burlington | Vermont | 05401 | — |
| Neurology and Neurosurgery Associates of Tacoma | Tacoma | Washington | 98405 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00056524, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 14, 2016 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00056524 live on ClinicalTrials.gov.