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Completed Phase 3 Interventional

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

ClinicalTrials.gov ID: NCT00058071

Public ClinicalTrials.gov record NCT00058071. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 9:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase III Trial of Amifostine vs. No Treatment for Platinum Induced Peripheral Neuropathy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Amifostine may be effective in relieving numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether amifostine is effective in treating peripheral neuropathy in patients who have received chemotherapy for cancer. PURPOSE: This randomized phase III trial is studying amifostine to see how well it works compared to observation in relieving numbness, tingling, and other symptoms of peripheral neuropathy in patients who have received platinum-based chemotherapy (such as cisplatin or carboplatin) for cancer.

Study identification

NCT ID
NCT00058071
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Gynecologic Oncology Group
Network
Enrollment
100 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2003
Primary completion
Nov 30, 2007
Completion
Not listed
Last update posted
Jul 8, 2013

Started 2003

United States locations

U.S. sites
57
U.S. states
19
U.S. cities
46
Facility City State ZIP Site status
Providence Saint Joseph Medical Center - Burbank Burbank California 91505
Moores UCSD Cancer Center La Jolla California 92093-0658
Jonsson Comprehensive Cancer Center at UCLA Los Angeles California 90095-1781
George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus New Britain Connecticut 06050
St. Vincent's Medical Center Jacksonville Florida 32204
Ella Milbank Foshay Cancer Center at Jupiter Medical Center Jupiter Florida 33458
Lakeland Regional Cancer Center at Lakeland Regional Medical Center Lakeland Florida 33805
University of Miami Sylvester Comprehensive Cancer Center - Miami Miami Florida 33136
Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center Savannah Georgia 31403-3089
Rush-Copley Cancer Care Center Aurora Illinois 60507
Robert H. Lurie Comprehensive Cancer Center at Northwestern University Chicago Illinois 60611-3013
University of Illinois Cancer Center Chicago Illinois 60612-7243
Ingalls Cancer Care Center at Ingalls Memorial Hospital Harvey Illinois 60426
Hinsdale Hematology Oncology Associates Hinsdale Illinois 60521
Joliet Oncology-Hematology Associates, Limited - West Joliet Illinois 60435
Regional Cancer Center at Memorial Medical Center Springfield Illinois 62781-0001
Carle Cancer Center at Carle Foundation Hospital Urbana Illinois 61801
CCOP - Carle Cancer Center Urbana Illinois 61801
Elkhart General Hospital Elkhart Indiana 46515
Howard Community Hospital at Howard Regional Health System Kokomo Indiana 46904
Center for Cancer Therapy at LaPorte Hospital and Health Services La Porte Indiana 46350
Saint Anthony Memorial Health Centers Michigan City Indiana 46360
CCOP - Northern Indiana CR Consortium South Bend Indiana 46601
Memorial Hospital of South Bend South Bend Indiana 46601
Saint Joseph Regional Medical Center South Bend Indiana 46617
Holden Comprehensive Cancer Center at University of Iowa Iowa City Iowa 52242
Louisville Oncology at Norton Cancer Center Louisville Kentucky 40202
William Beaumont Hospital - Royal Oak Campus Royal Oak Michigan 48073
Lakeland Regional Cancer Care Center - St. Joseph Saint Joseph Michigan 49085
University of Mississippi Cancer Clinic Jackson Mississippi 39216
CCOP - Cancer Research for the Ozarks Springfield Missouri 65802
St. John's Regional Health Center Springfield Missouri 65804
Hulston Cancer Center at Cox Medical Center South Springfield Missouri 65807
Siteman Cancer Center at Barnes-Jewish Hospital St Louis Missouri 63110
Women's Cancer Center - Lake Mead Las Vegas Nevada 89102
Sunrise Hospital and Medical Center Las Vegas Nevada 89109
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton Marlton New Jersey 08053
Cancer Institute of New Jersey at Cooper - Voorhees Voorhees Township New Jersey 08043
Fox Chase Virtua Health Cancer Program at Virtua West Jersey Voorhees Township New Jersey 08043
SUNY Downstate Medical Center Brooklyn New York 11203
Roswell Park Cancer Institute Buffalo New York 14263-0001
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill Chapel Hill North Carolina 27599-7295
Blumenthal Cancer Center at Carolinas Medical Center Charlotte North Carolina 28232-2861
FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center Pinehurst North Carolina 28374
McDowell Cancer Center at Akron General Medical Center Akron Ohio 44307
Aultman Hospital Cancer Center at Aultman Health Foundation Canton Ohio 44710-1799
Charles M. Barrett Cancer Center at University Hospital Cincinnati Ohio 45267
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Columbus Ohio 43210-1240
Riverside Methodist Hospital Cancer Care Columbus Ohio 43214-3998
Mount Carmel Health - West Hospital Columbus Ohio 43222
Hillcrest Cancer Center at Hillcrest Hospital Mayfield Heights Ohio 44124
Oklahoma University Cancer Institute Oklahoma City Oklahoma 73104
Cancer Care Associates - Midtown Tulsa Tulsa Oklahoma 74104
Rosenfeld Cancer Center at Abington Memorial Hospital Abington Pennsylvania 19001
Fox Chase Cancer Center - Philadelphia Philadelphia Pennsylvania 19111-2497
Avera Cancer Institute Sioux Falls South Dakota 57105
Sioux Valley Hospital and University of South Dakota Medical Center Sioux Falls South Dakota 57117-5039

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00058071, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 8, 2013 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00058071 live on ClinicalTrials.gov.

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