ClinicalTrials.gov record
Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer
ClinicalTrials.gov ID: NCT00063882
Public ClinicalTrials.gov record NCT00063882. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy With Brachytherapy Alone for Selected Patients With Intermediate Risk Prostatic Carcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor cells. It is not yet known whether interstitial brachytherapy is more effective with or without external-beam radiation therapy in treating prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of interstitial brachytherapy with or without external-beam radiation therapy in treating patients who have prostate cancer.
Study identification
- NCT ID
- NCT00063882
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 588 participants
Conditions and interventions
Conditions
Interventions
- Brachytherapy (100/110) Radiation
- Brachytherapy (125/145) Radiation
- External Beam Radiation Therapy Radiation
Radiation
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2003 (Type not available)
- Primary completion
- May 2017 (Actual)
- Completion
- Dec 22, 2022 (Actual)
- Last update posted
- Mar 5, 2026
2003 – 2022
United States locations
- U.S. sites
- 168
- U.S. states
- 28
- U.S. cities
- 125
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology Services Foundation | Phoenix | Arizona | 85013 | — |
| Auburn Radiation Oncology | Auburn | California | 95603 | — |
| Alta Bates Summit Comprehensive Cancer Center | Berkeley | California | 94704 | — |
| Peninsula Medical Center | Burlingame | California | 94010 | — |
| Radiation Oncology Centers - Cameron Park | Cameron Park | California | 95682 | — |
| Mercy Cancer Center at Mercy San Juan Medical Center | Carmichael | California | 95608 | — |
| East Bay Radiation Oncology Center | Castro Valley | California | 94546 | — |
| Valley Medical Oncology Consultants - Castro Valley | Castro Valley | California | 94546 | — |
| Valley Medical Oncology | Fremont | California | 94538 | — |
| California Cancer Center - Woodward Park Office | Fresno | California | 93720 | — |
| Kaiser Permanente Medical Center - Hayward | Hayward | California | 94545 | — |
| Contra Costa Regional Medical Center | Martinez | California | 94553-3156 | — |
| El Camino Hospital Cancer Center | Mountain View | California | 94040 | — |
| Sutter Health - Western Division Cancer Research Group | Novato | California | 94945 | — |
| Alta Bates Summit Medical Center - Summit Campus | Oakland | California | 94609 | — |
| Bay Area Breast Surgeons, Incorporated | Oakland | California | 94609 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Larry G Strieff MD Medical Corporation | Oakland | California | 94609 | — |
| Tom K Lee, Incorporated | Oakland | California | 94609 | — |
| Kaiser Permanente - Division of Research - Oakland | Oakland | California | 94611 | — |
| Kaiser Permanente Medical Center - Oakland | Oakland | California | 94611 | — |
| Kaiser Permanente Medical Center - Rancho Cordova | Rancho Cordova | California | 95670 | — |
| Kaiser Permanente Medical Center - Redwood City | Redwood City | California | 94063 | — |
| Kaiser Permanente Medical Center - Richmond | Richmond | California | 94801 | — |
| Rohnert Park Cancer Center | Rohnert Park | California | 94928 | — |
| Kaiser Permanente Medical Center - Roseville | Roseville | California | 95661 | — |
| Radiation Oncology Center - Roseville | Roseville | California | 95661 | — |
| Radiological Associates of Sacramento Medical Group, Incorporated | Sacramento | California | 95815 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| South Sacramento Cancer Center | Sacramento | California | 95823 | — |
| South Sacramento Kaiser-Permanente Medical Center | Sacramento | California | 95823 | — |
| Kaiser Permanente Medical Center - Sacramento | Sacramento | California | 95825 | — |
| Kaiser Permanente Medical Center - San Francisco Geary Campus | San Francisco | California | 94115 | — |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| California Pacific Medical Center - California Campus | San Francisco | California | 94118 | — |
| Kaiser Permanente Medical Center - Santa Teresa | San Jose | California | 95119 | — |
| Kaiser Foundation Hospital - San Rafael | San Rafael | California | 94903 | — |
| Kaiser Permanente Medical Center - Santa Clara Kiely Campus | Santa Clara | California | 95051 | — |
| Not listed | Santa Clara | California | 95051 | — |
| Kaiser Permanente Medical Center - Santa Rosa | Santa Rosa | California | 95403 | — |
| Kaiser Permanente Medical Center - South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente Medical Facility - Stockton | Stockton | California | 95210 | — |
| Solano Radiation Oncology Center | Vacaville | California | 95687 | — |
| Sutter Solano Medical Center | Vallejo | California | 94589 | — |
| Kaiser Permanente Medical Center - Walnut Creek | Walnut Creek | California | 94596 | — |
| Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| Hospital of Saint Raphael | New Haven | Connecticut | 06511 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Ella Milbank Foshay Cancer Center at Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Cancer Institute at St. John's Hospital | Springfield | Illinois | 62702 | — |
| Regional Cancer Center at Memorial Medical Center | Springfield | Illinois | 62781-0001 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| CCOP - Kansas City | Prairie Village | Kansas | 66208 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| St. Agnes Hospital Cancer Center | Baltimore | Maryland | 21229 | — |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | — |
| Shields Radiation Oncology Center - Mansfield | Mansfield | Massachusetts | 02048 | — |
| South Suburban Oncology Center | Quincy | Massachusetts | 02169 | — |
| Winchester Hospital Radiation Oncology Center | Winchester | Massachusetts | 01890 | — |
| Hickman Cancer Center at Bixby Medical Center | Adrian | Michigan | 49221 | — |
| Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | 48106-0995 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| Oakwood Cancer Center at Oakwood Hospital and Medical Center | Dearborn | Michigan | 48123-2500 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | 48236 | — |
| Foote Memorial Hospital | Jackson | Michigan | 49201 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912-1811 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| St. Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | 48060 | — |
| Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | 48601 | — |
| St. John Macomb Hospital | Warren | Michigan | 48093 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters | City of Saint Peters | Missouri | 63376 | — |
| Saint Luke's Cancer Institute at Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| St. Joseph Medical Center | Kansas City | Missouri | 64114 | — |
| North Kansas City Hospital | Kansas City | Missouri | 64116 | — |
| Parvin Radiation Oncology | Kansas City | Missouri | 64116 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Liberty Hospital | Liberty | Missouri | 64068 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| Saint Joseph Oncology, Incorporated | Saint Joseph | Missouri | 64507 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St Louis | Missouri | 63110 | — |
| Barnes-Jewish West County Hospital | St Louis | Missouri | 63141 | — |
| CCOP - Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Nevada Cancer Institute | Las Vegas | Nevada | 89135 | — |
| Renown Institute for Cancer at Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Kingsbury Center for Cancer Care at Cheshire Medical Center | Keene | New Hampshire | 03431 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0002 | — |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | Marlton | New Jersey | 08053 | — |
| Fox Chase Virtua Health Cancer Program at Virtua West Jersey | Voorhees Township | New Jersey | 08043 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Sands Cancer Center | Canandiaqua | New York | 14424 | — |
| Beth Israel Medical Center - Petrie Division | New York | New York | 10003-3803 | — |
| Highland Hospital of Rochester | Rochester | New York | 14620 | — |
| University Radiation Oncology at Parkridge Hospital | Rochester | New York | 14626 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Coleman Radiation Oncology Center at Carter General Hospital | Morehead City | North Carolina | 28557 | — |
| CarolinaEast Cancer Care | New Bern | North Carolina | 28560 | — |
| South Atlantic Radiation Oncology, LLC | Supply | North Carolina | 28462 | — |
| Coastal Carolina Radiation Oncology Center | Wilmington | North Carolina | 28401 | — |
| Summa Center for Cancer Care at Akron City Hospital | Akron | Ohio | 44309-2090 | — |
| Radiation Oncology Center | Alliance | Ohio | 44601 | — |
| Barberton Citizens Hospital | Barberton | Ohio | 44203 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210-1240 | — |
| Riverside Methodist Hospital Cancer Care | Columbus | Ohio | 43214-3998 | — |
| CCOP - Columbus | Columbus | Ohio | 43215 | — |
| Grant Medical Center Cancer Care | Columbus | Ohio | 43215 | — |
| Mount Carmel Health - West Hospital | Columbus | Ohio | 43222 | — |
| Doctors Hospital at Ohio Health | Columbus | Ohio | 43228 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Community Cancer Center | Elyria | Ohio | 44035 | — |
| Hematology Oncology Center | Elyria | Ohio | 44035 | — |
| Lima Memorial Hospital | Lima | Ohio | 45804 | — |
| Strecker Cancer Center at Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Northwest Ohio Oncology Center | Maumee | Ohio | 43537-1839 | — |
| Licking Memorial Cancer Care Program at Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| St. Charles Mercy Hospital | Oregon | Ohio | 43616 | — |
| Cancer Care Center, Incorporated | Salem | Ohio | 44460 | — |
| North Coast Cancer Care, Incorporated | Sandusky | Ohio | 44870 | — |
| Community Hospital of Springfield and Clark County | Springfield | Ohio | 45505 | — |
| Flower Hospital Cancer Center | Sylvania | Ohio | 43560 | — |
| Mercy Hospital of Tiffin | Tiffin | Ohio | 44883 | — |
| Toledo Hospital | Toledo | Ohio | 43606 | — |
| St. Vincent Mercy Medical Center | Toledo | Ohio | 43608 | — |
| Medical University of Ohio Cancer Center | Toledo | Ohio | 43614 | — |
| CCOP - Toledo Community Hospital | Toledo | Ohio | 43617 | — |
| St. Anne Mercy Hospital | Toledo | Ohio | 43623 | — |
| Toledo Clinic, Incorporated - Main Clinic | Toledo | Ohio | 43623 | — |
| Mount Carmel St. Ann's Cancer Center | Westerville | Ohio | 43081 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Genesis - Good Samaritan Hospital | Zanesville | Ohio | 43701 | — |
| Geisinger Cancer Institute at Geisinger Health | Danville | Pennsylvania | 17822-0001 | — |
| Fox Chase Cancer Center - Philadelphia | Philadelphia | Pennsylvania | 19111-2497 | — |
| McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | — |
| Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| York Cancer Center at Apple Hill Medical Center | York | Pennsylvania | 17405 | — |
| M. D. Anderson Cancer Center at University of Texas | Houston | Texas | 77030-4009 | — |
| Sandra L. Maxwell Cancer Center | Cedar City | Utah | 84720 | — |
| Logan Regional Hospital | Logan | Utah | 84321 | — |
| Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | Murray | Utah | 84157 | — |
| Val and Ann Browning Cancer Center at McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84604 | — |
| Utah Cancer Specialists at UCS Cancer Center | Salt Lake City | Utah | 84106 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Regional Medical Center - East Campus | St. George | Utah | 84770 | — |
| Norris Cotton Cancer Center - North | Saint Johnsbury | Vermont | 05819 | — |
| Fredericksburg Oncology, Incorporated | Fredericksburg | Virginia | 22401 | — |
| Veterans Affairs Medical Center - Richmond | Richmond | Virginia | 23249 | — |
| St. Francis Hospital | Federal Way | Washington | 98003 | — |
| Good Samaritan Cancer Center | Puyallup | Washington | 98372 | — |
| Franciscan Cancer Center at St. Joseph Medical Center | Tacoma | Washington | 98405-3004 | — |
| CCOP - Northwest | Tacoma | Washington | 98405 | — |
| MultiCare Regional Cancer Center at Tacoma General Hospital | Tacoma | Washington | 98405 | — |
| Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia-Saint Mary's Cancer Care Center | Milwaukee | Wisconsin | 53211 | — |
| Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| All Saints Cancer Center at Wheaton Franciscan Healthcare | Racine | Wisconsin | 53405 | — |
| West Allis Memorial Hospital | West Allis | Wisconsin | 53227 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00063882, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 5, 2026 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00063882 live on ClinicalTrials.gov.