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Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Trial of Rosiglitazone for Ulcerative Colitis

ClinicalTrials.gov ID: NCT00065065

Public ClinicalTrials.gov record NCT00065065. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 9, 2026, 1:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Placebo-controlled Trial of Rosiglitazone for Treatment of Ulcerative Colitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multicenter, randomized, double-blind, placebo-controlled study evaluating rosiglitazone: 4 mg tablets or placebo tablets administered orally twice daily for 12 weeks. The purpose of the study is to evaluate the efficacy and safety of rosiglitazone in the treatment of mild to moderately active ulcerative colitis. Disease activity will be measured using a standard disease activity index. Calculation of the index requires patients to undergo flexible sigmoidoscopy at the start of the study and at week 12.

Study identification

NCT ID
NCT00065065
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
James Lewis
Other
Enrollment
105 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2002
Primary completion
Dec 31, 2007
Completion
Dec 31, 2007
Last update posted
Jan 15, 2018

2002 – 2008

United States locations

U.S. sites
13
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Atlanta Gastroenterology Associates Atlanta Georgia 30342
University of Chicago Hospitals Chicago Illinois 60637
Metropolitan Gastroenterology Group Practice/Chevy Chase Clinical Research Chevy Chase Maryland 20815
Maryland Digestive Diseases Research Laurel Maryland 20707
Capitol Gastroenterology Consultants Silver Spring Maryland 20901
Massachusetts General Hospital Boston Massachusetts 02114
Minnesota Gastroenterology Plymouth Minnesota 55446
Atlantic Gastroenterology Associates Egg Harbor New Jersey 08234
Wake Research Associates Raleigh North Carolina 27612
University Hospitals of Cleveland Cleveland Ohio 44106
The Cleveland Clinic Foundation Cleveland Ohio 44195
Avamar Center for Endoscopy Warren Ohio 44484
University of Pennsylvania - Presbyterian Medical Center Philadelphia Pennsylvania 19104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00065065, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 15, 2018 · Synced Sep 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00065065 live on ClinicalTrials.gov.

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