Comparison of Entecavir to Adefovir in Chronic Hepatitis B Virus (HBV) Patients With Hepatic Decompensation
Public ClinicalTrials.gov record NCT00065507. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Comparison of the Efficacy and Safety of Entecavir Versus Adefovir in Subjects Chronically Infected With Hepatitis B Virus and Evidence of Hepatic Decompensation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase IIIb comparative study of entecavir 1.0 mg once daily (QD) vs. adefovir 10 mg QD in patients who have chronic hepatitis B infection and hepatic decompensation. The patients are treated for 96 weeks after the last subject is randomized.
Study identification
- NCT ID
- NCT00065507
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 195 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2003 (Type not available)
- Primary completion
- Oct 2008 (Actual)
- Completion
- May 2013 (Actual)
- Last update posted
- Jun 24, 2013
2003 – 2013
United States locations
- U.S. sites
- 16
- U.S. states
- 13
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research And Education, Inc. | San Diego | California | 92115 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06520 | — |
| University Of Miami School Of Medicine | Miami | Florida | 33136 | — |
| Pediatric Gasteroenterology | Atlanta | Georgia | 30342 | — |
| Hawaii Medical Center East | Honolulu | Hawaii | 96817 | — |
| Indiana University Med Center | Indianapolis | Indiana | 46202-5121 | — |
| The Cht Liver Research Center | Louisville | Kentucky | 40292 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Henry Ford Health System Irb | Detroit | Michigan | 48202 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia Presbyterian Medical Center (Cpmc) | New York | New York | 10032 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| Ut Southwestern Medical Center | Dallas | Texas | 75390-9151 | — |
| Mcguire Dvamc | Richmond | Virginia | 23249 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00065507, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2013 · Synced Nov 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00065507 live on ClinicalTrials.gov.