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Completed Phase 3 Interventional Results available

Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy

ClinicalTrials.gov ID: NCT00066170

Public ClinicalTrials.gov record NCT00066170. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 1:15 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Parallel-Group, Multi-Center Trial Comparing the Effects of Orally Administered Xyrem (Sodium Oxybate) and Modafinil With Placebo in Treatment of Daytime Sleepiness in Narcolepsy

Study identification

NCT ID
NCT00066170
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Jazz Pharmaceuticals
Industry
Enrollment
231 participants

Conditions and interventions

Conditions

Interventions

  • Modafinil (Placebo) Drug
  • Modafinil at established dose Drug
  • Xyrem Drug
  • Xyrem Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2003
Primary completion
Jun 30, 2004
Completion
Oct 31, 2004
Last update posted
Dec 28, 2011

2003 – 2004

United States locations

U.S. sites
36
U.S. states
18
U.S. cities
32
Facility City State ZIP Site status
Pulmonary Associates, PA Phoenix Arizona 85006
St. Jude Medical Center -- Sleep Disorders Institute Fullerton California 92835
Pacific Sleep Medicine Services, Inc. Los Angeles California 90048
Neuro-Therapeutics, Inc. Pasadena California 91105
Pacific Sleep Medicine Services, Inc. San Diego California 92121
Stanford Sleep Disorders Clinic Stanford California 94305
Clinical Research Group of St. Petersburg, Inc. St. Petersburg Florida 33707
Peoria Pulmonary Associates, Ltd Peoria Illinois 61603
The Center for Sleep and Wake Disorders/Midwest Neurology Danville Indiana 46122
Graves Gilbert Clinic Bowling Green Kentucky 42101
Community Research & Sleep Management Institute Crestview Hills Kentucky 41017
Chest Medicine Associates DBA -- Sleep Medicine Specialists Louisville Kentucky 40217
The Center for Sleep & Wake Disorders Chevy Chase Maryland 20815
Sleep Disorders Center -- Union Hospital of Cecil County Elkton Maryland 21921
Sleep Medicine Associates of Maryland Towson Maryland 21204
Henry Ford Hospital Detroit Michigan 48202
Washington University Sleep Center St Louis Missouri 63108
New Jersey Neuroscience Institute at JFK Medical Center Edison New Jersey 08818
Sleep Disorders Center of Rochester Rochester New York 14618
Strong Sleep Disorders Center Rochester New York 14618
Raleigh Neurology Associates Raleigh North Carolina 27607
ALL-TRIALS Clinical Research, LLC -- Summit Sleep Disorder Winston-Salem North Carolina 27103
Cincinnati Clinic & Sleep Management Institute Cincinnati Ohio 45219
Community Research Management Associates,Inc. Cincinnati Ohio 45219
CSC Research -- Grove City Sleep Diagnostic Center Grove City Ohio 43123
Lehigh Valley Hospital Sleep Disorders Center Allentown Pennsylvania 18105
Capital Region Sleep Disorder Center Carlisle Pennsylvania 17013
Center for Sleep Medicine Lafayette Hill Pennsylvania 19444
Lowcountry Lung and Critical Care, PA Charleston South Carolina 29406-7108
SleepMed of South Carolina Columbia South Carolina 29220
SDHRF Clinical Research Center Sioux Falls South Dakota 57104
Sioux Valley Clinic -- Pulmonary Sioux Falls South Dakota 57105
Sleep Disorders Center Sioux Falls South Dakota 57105
Bhupesh Dihenia, MD Lubbock Texas 79410
SLEEP WALKER -- Sleep Disorders Center & Neurodiagnostics--Lung Diagnostics, Ltd. San Antonio Texas 78229
Vermont Medical Sleep Disorders Center, Inc. Essex Junction Vermont 05452

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00066170, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 28, 2011 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00066170 live on ClinicalTrials.gov.

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