ClinicalTrials.gov record
Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer
ClinicalTrials.gov ID: NCT00066690
Public ClinicalTrials.gov record NCT00066690. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Trial Evaluating the Role of Ovarian Function Suppression and the Role of Exemestane as Adjuvant Therapies for Premenopausal Women With Endocrine Responsive Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Estrogen can stimulate the growth of breast tumor cells. Ovarian function suppression combined with hormone therapy using tamoxifen or exemestane may fight breast cancer by reducing the production of estrogen. It is not yet known whether suppression of ovarian function plus either tamoxifen or exemestane is more effective than tamoxifen alone in preventing the recurrence of hormone-responsive breast cancer. PURPOSE: This randomized phase III trial studies ovarian suppression with either tamoxifen or exemestane to see how well they work compared to tamoxifen alone in treating premenopausal women who have undergone surgery for hormone-responsive breast cancer.
Study identification
- NCT ID
- NCT00066690
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,066 participants
Conditions and interventions
Conditions
Interventions
- Exemestane Drug
- Laboratory Biomarker Analysis Other
- Oophorectomy Procedure
- Quality-of-Life Assessment Other
- Radiation Therapy Radiation
- Tamoxifen Drug
- Triptorelin Drug
Drug · Other · Procedure + 1 more
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 17, 2003 (Actual)
- Primary completion
- May 2014 (Actual)
- Completion
- Nov 6, 2024 (Actual)
- Last update posted
- Aug 26, 2026
2003 – 2024
United States locations
- U.S. sites
- 480
- U.S. states
- 46
- U.S. cities
- 326
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Mayo Clinic in Arizona | Scottsdale | Arizona | 85259 | — |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | 94704 | — |
| Mills - Peninsula Hospitals | Burlingame | California | 94010 | — |
| East Bay Radiation Oncology Center | Castro Valley | California | 94546 | — |
| Valley Medical Oncology Consultants-Castro Valley | Castro Valley | California | 94546 | — |
| John Muir Medical Center-Concord Campus | Concord | California | 94520 | — |
| Bay Area Breast Surgeons Inc | Emeryville | California | 94608 | — |
| Kaiser Permanente-Fremont | Fremont | California | 94538 | — |
| Valley Medical Oncology Consultants-Fremont | Fremont | California | 94538 | — |
| Glendale Memorial Hospital and Health Center | Glendale | California | 91204 | — |
| Marin General Hospital | Greenbrae | California | 94904 | — |
| Scripps Cancer Center | La Jolla | California | 92037 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles | California | 90095 | — |
| Contra Costa Regional Medical Center | Martinez | California | 94553-3156 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| Palo Alto Medical Foundation-Camino Division | Mountain View | California | 94040 | — |
| Sutter Cancer Research Consortium | Novato | California | 94945 | — |
| Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Hematology and Oncology Associates-Oakland | Oakland | California | 94609 | — |
| Tom K Lee Inc | Oakland | California | 94609 | — |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | — |
| Palo Alto Medical Foundation Health Care | Palo Alto | California | 94301 | — |
| Stanford Cancer Institute | Palo Alto | California | 94304 | — |
| Valley Medical Oncology Consultants | Pleasanton | California | 94588 | — |
| Eisenhower Medical Center | Rancho Mirage | California | 92270 | — |
| Mercy Regional Cancer Center | Redding | California | 96001 | — |
| Kaiser Permanente-Redwood City | Redwood City | California | 94063 | — |
| Kaiser Permanente-Richmond | Richmond | California | 94801 | — |
| Kaiser Permanente-Roseville | Roseville | California | 95661 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Kaiser Permanente-South Sacramento | Sacramento | California | 95823 | — |
| Kaiser Permanente - Sacramento | Sacramento | California | 95825 | — |
| Salinas Valley Memorial | Salinas | California | 93901 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| Kaiser Permanente-San Diego Mission | San Diego | California | 92108 | — |
| Veterans Administration-San Diego Medical Center | San Diego | California | 92161 | — |
| San Francisco General Hospital | San Francisco | California | 94110 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| Kaiser Permanente-San Francisco | San Francisco | California | 94115 | — |
| UCSF Medical Center-Mount Zion | San Francisco | California | 94115 | — |
| Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | 95119 | — |
| Kaiser Permanente San Leandro | San Leandro | California | 94577 | — |
| Kaiser Permanente-San Rafael | San Rafael | California | 94903 | — |
| Santa Rosa Memorial Hospital | Sana Rosa | California | 95405 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051 | — |
| Kaiser Permanente-Santa Rosa | Santa Rosa | California | 95403 | — |
| Kaiser Permanente-South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente-Vallejo | Vallejo | California | 94589 | — |
| Kaiser Permanente-Walnut Creek | Walnut Creek | California | 94596 | — |
| John Muir Medical Center-Walnut Creek | Walnut Creek | California | 94598 | — |
| The Medical Center of Aurora | Aurora | Colorado | 80012 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Memorial Hospital Colorado Springs | Colorado Springs | Colorado | 80909 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | 80218 | — |
| SCL Health Saint Joseph Hospital | Denver | Colorado | 80218 | — |
| Denver Veterans Administration Medical Center | Denver | Colorado | 80220 | — |
| Rose Medical Center | Denver | Colorado | 80220 | — |
| Colorado Cancer Research Program NCORP | Denver | Colorado | 80222 | — |
| The Shaw Regional Cancer Center | Edwards | Colorado | 81632 | — |
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Front Range Cancer Specialists | Fort Collins | Colorado | 80528 | — |
| North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| Saint Anthony Hospital | Lakewood | Colorado | 80228 | — |
| Sky Ridge Medical Center | Lone Tree | Colorado | 80124 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| North Suburban Medical Center | Thornton | Colorado | 80229 | — |
| SCL Health Lutheran Medical Center | Wheat Ridge | Colorado | 80033 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Eastern Connecticut Hematology and Oncology Associates | Norwich | Connecticut | 06360 | — |
| Stamford Hospital/Bennett Cancer Center | Stamford | Connecticut | 06904 | — |
| Charlotte Hungerford Hospital Center for Cancer Care | Torrington | Connecticut | 06790 | — |
| Bayhealth Medical Center at Kent General | Dover | Delaware | 19901 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| Nanticoke Memorial Hospital | Seaford | Delaware | 19973 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Cancer Research Network Inc | Boca Raton | Florida | 33428 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital | Hollywood | Florida | 33021 | — |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | — |
| Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Florida Cancer Specialists - Sarasota Downtown | Sarasota | Florida | 34236 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Emory University/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Atlanta Regional CCOP | Atlanta | Georgia | 30342 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| Augusta Oncology Associates PC-Saint Sebastian | Augusta | Georgia | 30901 | — |
| Well Star Cobb Hospital | Austell | Georgia | 30106 | — |
| John B Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Dekalb Medical Center | Decatur | Georgia | 30033 | — |
| Gwinnett Medical Center | Lawrenceville | Georgia | 30045 | — |
| Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Southern Regional Medical Center | Riverdale | Georgia | 30274 | — |
| Harbin Clinic Medical Oncology and Clinical Research | Rome | Georgia | 30165 | — |
| Memorial University Medical Center | Savannah | Georgia | 31404 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859 | — |
| Saint Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Graham Hospital Association | Canton | Illinois | 61520 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Weiss Memorial Hospital | Chicago | Illinois | 60640 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Heartland Cancer Research NCORP | Decatur | Illinois | 62526 | — |
| Eureka Hospital | Eureka | Illinois | 61530 | — |
| Galesburg Cottage Hospital | Galesburg | Illinois | 61401 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Western Illinois Cancer Treatment Center | Galesburg | Illinois | 61401 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Hopedale Medical Complex - Hospital | Hopedale | Illinois | 61747 | — |
| Kewanee Hospital | Kewanee | Illinois | 61443 | — |
| Mcdonough District Hospital | Macomb | Illinois | 61455 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Edward Hospital/Cancer Center | Naperville | Illinois | 60540 | — |
| Bromenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Community Cancer Center Foundation | Normal | Illinois | 61761 | — |
| Ottawa Regional Hospital and Healthcare Center | Ottawa | Illinois | 61350 | — |
| OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center | Pekin | Illinois | 61554 | — |
| Pekin Hospital | Pekin | Illinois | 61554 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61603 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois Valley Hospital | Peru | Illinois | 61354 | — |
| Valley Radiation Oncology | Peru | Illinois | 61354 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| OSF Saint Anthony Medical Center | Rockford | Illinois | 61108 | — |
| Sarah Culbertson Memorial Hospital | Rushville | Illinois | 62681 | — |
| Saint Margaret's Hospital | Spring Valley | Illinois | 61362 | — |
| Memorial Medical Center | Springfield | Illinois | 62781 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Fort Wayne Medical Oncology and Hematology Inc-Parkview | Fort Wayne | Indiana | 46845 | — |
| Sidney and Lois Eskenazi Hospital | Indianapolis | Indiana | 46202 | — |
| Community Hospital East | Indianapolis | Indiana | 46219 | — |
| Community Regional Cancer Care-North | Indianapolis | Indiana | 46256 | — |
| Saint Vincent Hospital and Health Care Center | Indianapolis | Indiana | 46260 | — |
| IU Health La Porte Hospital | La Porte | Indiana | 46350 | — |
| IU Health Arnett Cancer Care | Lafayette | Indiana | 47904 | — |
| Horizon Oncology Center | Lafayette | Indiana | 47905 | — |
| Saint Joseph Regional Medical Center - Mishawaka | Mishawaka | Indiana | 46545 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Northern Indiana Cancer Research Consortium | South Bend | Indiana | 46628 | — |
| McFarland Clinic PC-William R Bliss Cancer Center | Ames | Iowa | 50010 | — |
| Physicians' Clinic of Iowa PC | Cedar Rapids | Iowa | 52402 | — |
| Saint Luke's Hospital | Cedar Rapids | Iowa | 52402 | — |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | — |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | 50325 | — |
| Genesis Medical Center - East Campus | Davenport | Iowa | 52803 | — |
| Mercy Capitol | Des Moines | Iowa | 50307 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Iowa-Wide Oncology Research Coalition NCORP | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| Finley Hospital | Dubuque | Iowa | 52001 | — |
| Medical Associates Clinic PC | Dubuque | Iowa | 52001 | — |
| Mercy Medical Center - North Iowa | Mason City | Iowa | 50401 | — |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | — |
| Memorial Hospital of Arkansas City | Arkansas City | Kansas | 67005 | — |
| Cancer Center of Kansas - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas-Independence | Independence | Kansas | 67301 | — |
| Cancer Center of Kansas-Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas - McPherson | McPherson | Kansas | 67460 | — |
| Cancer Center of Kansas - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas - Salina | Salina | Kansas | 67401 | — |
| Saint Francis Hospital and Medical Center - Topeka | Topeka | Kansas | 66606 | — |
| Cancer Center of Kansas - Wellington | Wellington | Kansas | 67152 | — |
| Associates In Womens Health | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas - Main Office | Wichita | Kansas | 67214 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wichita NCI Community Oncology Research Program | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Winfield | Winfield | Kansas | 67156 | — |
| Louisiana State University Health Sciences Center Shreveport | Shreveport | Louisiana | 71103 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Mercy Hospital | Portland | Maine | 04101 | — |
| Anne Arundel Medical Center | Annapolis | Maryland | 21401 | — |
| Harbor Hospital Center | Baltimore | Maryland | 21225 | — |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | — |
| Suburban Hospital | Bethesda | Maryland | 20814 | — |
| Union Hospital of Cecil County | Elkton MD | Maryland | 21921 | — |
| Kaiser Permanente - Largo Medical Center | Largo | Maryland | 20774 | — |
| Kaiser Permanente - Towson Medical Center | Lutherville | Maryland | 21093 | — |
| Kaiser Permanente - Shady Grove Medical Center | Rockville | Maryland | 20850 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Brigham and Women's Faulkner Hospital | Boston | Massachusetts | 02130 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Emerson Hospital/MGH Cancer Center | Concord | Massachusetts | 01742 | — |
| Mass General/North Shore Cancer Center | Danvers | Massachusetts | 01923 | — |
| MetroWest Medical Center-Framingham Union Hospital | Framingham | Massachusetts | 01702 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Newton-Wellesley Hospital | Newton | Massachusetts | 02462 | — |
| South Shore Hospital | South Weymouth | Massachusetts | 02190 | — |
| Bixby Medical Center | Adrian | Michigan | 49221 | — |
| Hickman Cancer Center | Adrian | Michigan | 49221 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| Michigan Cancer Research Consortium NCORP | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Saint John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Green Bay Oncology - Escanaba | Escanaba | Michigan | 49829 | — |
| Genesys Regional Medical Center-West Flint Campus | Flint | Michigan | 48532 | — |
| Cancer Research Consortium of West Michigan NCORP | Grand Rapids | Michigan | 49503 | — |
| Green Bay Oncology - Iron Mountain | Iron Mountain | Michigan | 49801 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| Marquette General Hospital | Marquette | Michigan | 49855 | — |
| Mid-Michigan Medical Center - Midland | Midland | Michigan | 48670 | — |
| Mercy Memorial Hospital | Monroe | Michigan | 48162 | — |
| Toledo Clinic Cancer Centers-Monroe | Monroe | Michigan | 48162 | — |
| William Beaumont Hospital-Royal Oak | Royal Oak | Michigan | 48073 | — |
| Saint Mary's of Michigan | Saginaw | Michigan | 48601 | — |
| Lakeland Hospital | Saint Joseph | Michigan | 49085 | — |
| Saint John Macomb-Oakland Hospital | Warren | Michigan | 48093 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Fairview-Southdale Hospital | Edina | Minnesota | 55435 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Hutchinson Area Health Care | Hutchinson | Minnesota | 55350 | — |
| Meeker County Memorial Hospital | Litchfield | Minnesota | 55355 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Virginia Piper Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Saint Joseph's Hospital - Healtheast | Saint Paul | Minnesota | 55102 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology and Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Woodwinds Health Campus | Woodbury | Minnesota | 55125 | — |
| Keesler Medical Center | Kessler Air Force Base | Mississippi | 39534 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Saint Anthony's Medical Center | St Louis | Missouri | 63128 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Montana Cancer Consortium NCORP | Billings | Montana | 59101 | — |
| Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Benefis Healthcare-West Campus | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| New Hampshire Oncology Hematology PA-Concord | Concord | New Hampshire | 03301 | — |
| Exeter Hospital | Exeter | New Hampshire | 03833 | — |
| New Hampshire Oncology Hematology PA-Hooksett | Hooksett | New Hampshire | 03106 | — |
| Cheshire Medical Center-Dartmouth-Hitchcock Keene | Keene | New Hampshire | 03431 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Elliot Hospital | Manchester | New Hampshire | 03103 | — |
| Frisbie Hospital | Rochester | New Hampshire | 03867 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| The Cancer Institute of New Jersey Hamilton | Hamilton | New Jersey | 08690 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Virtua Memorial | Mount Holly | New Jersey | 08060 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Inspira Medical Center Vineland | Vineland | New Jersey | 08360 | — |
| Virtua Voorhees | Voorhees Township | New Jersey | 08043 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87102 | — |
| Hematology Oncology Associates | Albuquerque | New Mexico | 87106 | — |
| Presbyterian Kaseman Hospital | Albuquerque | New Mexico | 87110 | — |
| Kings County Hospital | Brooklyn | New York | 11203 | — |
| State University of New York Downstate Medical Center | Brooklyn | New York | 11203 | — |
| University Hospital of Brooklyn | Brooklyn | New York | 11203 | — |
| Brookdale Hospital Medical Center | Brooklyn | New York | 11212 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Adirondack Cancer Center | Glens Falls | New York | 12801 | — |
| Northwell Health NCORP | Lake Success | New York | 11042 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| Saint Vincent's Hospital and Medical Center of New York | New York | New York | 10011 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Weill Medical College of Cornell University | New York | New York | 10065 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| Montefiore Medical Center-Weiler Hospital | The Bronx | New York | 10461 | — |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467-2490 | — |
| Mission Hospital-Memorial Campus | Asheville | North Carolina | 28801 | — |
| Hope Women's Cancer Centers-Asheville | Asheville | North Carolina | 28816 | — |
| Cone Health Cancer Center at Alamance Regional | Burlington | North Carolina | 27216 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Carolinas HealthCare System NorthEast | Concord | North Carolina | 28025 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27534 | — |
| FirstHealth of the Carolinas-Moore Regional Hosiptal | Pinehurst | North Carolina | 28374 | — |
| Rutherford Hospital | Rutherfordton | North Carolina | 28139 | — |
| Novant Health Forsyth Medical Center | Winston-Salem | North Carolina | 27103 | — |
| Southeast Clinical Oncology Research (SCOR) Consortium NCORP | Winston-Salem | North Carolina | 27104 | — |
| Mid Dakota Clinic | Bismarck | North Dakota | 58501 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Altru Cancer Center | Grand Forks | North Dakota | 58201 | — |
| Altru Hospital | Grand Forks | North Dakota | 58201 | — |
| Trinity Cancer Care Center | Minot | North Dakota | 58701 | — |
| Toledo Clinic Cancer Centers-Bowling Green | Bowling Green | Ohio | 43402 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Columbus NCI Community Oncology Research Program | Columbus | Ohio | 43215 | — |
| Grant Medical Center | Columbus | Ohio | 43215 | — |
| Mount Carmel Health Center West | Columbus | Ohio | 43222 | — |
| Doctors Hospital | Columbus | Ohio | 43228 | — |
| Good Samaritan Hospital - Dayton | Dayton | Ohio | 45406 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Samaritan North Health Center | Dayton | Ohio | 45415 | — |
| Dayton NCI Community Oncology Research Program | Dayton | Ohio | 45420 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Lima Memorial Hospital | Lima | Ohio | 45804 | — |
| Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | 43537 | — |
| Toledo Radiation Oncology at Northwest Ohio Onocolgy Center | Maumee | Ohio | 43537 | — |
| Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Saint Charles Hospital | Oregon | Ohio | 43616 | — |
| Toledo Clinic Cancer Centers-Oregon | Oregon | Ohio | 43616 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45505 | — |
| Flower Hospital | Sylvania | Ohio | 43560 | — |
| The Toledo Hospital/Toledo Children's Hospital | Toledo | Ohio | 43606 | — |
| Saint Vincent Mercy Medical Center | Toledo | Ohio | 43608 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| Toledo Community Hospital Oncology Program CCOP | Toledo | Ohio | 43617 | — |
| Mercy Saint Anne Hospital | Toledo | Ohio | 43623 | — |
| Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | 43623 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Fulton County Health Center | Wauseon | Ohio | 43567 | — |
| Saint Ann's Hospital | Westerville | Ohio | 43081 | — |
| Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio | 44691 | — |
| Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Tod Children's Hospital - Forum Health | Youngstown | Ohio | 44501 | — |
| Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | 43701 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Saint Charles Medical Center-Bend | Bend | Oregon | 97701 | — |
| Legacy Mount Hood Medical Center | Gresham | Oregon | 97030 | — |
| Providence Milwaukie Hospital | Milwaukie | Oregon | 97222 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Western Oncology Research Consortium | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Kaiser Permanente | Portland | Oregon | 97227 | — |
| Legacy Emanuel Hospital and Health Center | Portland | Oregon | 97227 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| Saint Luke's University Hospital-Bethlehem Campus | Bethlehem | Pennsylvania | 18015 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Geisinger Medical Center-Cancer Center Hazleton | Hazleton | Pennsylvania | 18201 | — |
| Penn State Hershey Cancer Institute-Clinical Trials Office | Hershey | Pennsylvania | 17033-0850 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| Saint Mary Medical and Regional Cancer Center | Langhorne | Pennsylvania | 19047 | — |
| Lewistown Hospital | Lewistown | Pennsylvania | 17044 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Aria Health-Torresdale Campus | Philadelphia | Pennsylvania | 19114 | — |
| Chestnut Hill Health System | Philadelphia | Pennsylvania | 19118 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | 15232 | — |
| Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Scranton Hematology Oncology | Scranton | Pennsylvania | 18510 | — |
| Grand View Hospital | Sellersville | Pennsylvania | 18960 | — |
| Geisinger Medical Group | State College | Pennsylvania | 16801 | — |
| Mount Nittany Medical Center | State College | Pennsylvania | 16803 | — |
| Chester County Hospital | West Chester | Pennsylvania | 19380 | — |
| Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| WellSpan Health-York Hospital | York | Pennsylvania | 17403 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Women and Infants Hospital | Providence | Rhode Island | 02905 | — |
| Miriam Hospital | Providence | Rhode Island | 02906 | — |
| AnMed Health Hospital | Anderson | South Carolina | 29621 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Sanford Cancer Center-Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Avera McKennan Hospital and University Health Center | Sioux Falls | South Dakota | 57105 | — |
| Medical X-Ray Center | Sioux Falls | South Dakota | 57105 | — |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | — |
| Erlanger Medical Center | Chattanooga | Tennessee | 37403 | — |
| Memorial Hospital | Chattanooga | Tennessee | 37404 | — |
| Jones Clinic | Germantown | Tennessee | 38138 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Nashville Oncology Associates PC | Nashville | Tennessee | 37203 | — |
| Meharry Medical College | Nashville | Tennessee | 37208 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Zale Lipshy University Hospital | Dallas | Texas | 75235 | — |
| Clements University Hospital | Dallas | Texas | 75390 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas | 77030 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| Doctor's Hospital of Laredo | Laredo | Texas | 78041 | — |
| Covenant Medical Center-Lakeside | Lubbock | Texas | 79410 | — |
| Cancer Therapy and Research Center at The UT Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Southwestern Vermont Medical Center | Bennington | Vermont | 05201 | — |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | — |
| University of Vermont College of Medicine | Burlington | Vermont | 05405 | — |
| Kaiser Permanente - Fair Oaks Medical Center | Fairfax | Virginia | 22033 | — |
| Fredericksburg Oncology Inc | Fredericksburg | Virginia | 22401 | — |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | — |
| MultiCare Auburn Medical Center | Auburn | Washington | 98001 | — |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | — |
| Saint Francis Hospital | Federal Way | Washington | 98003 | — |
| Saint Clare Hospital | Lakewood | Washington | 98499 | — |
| Providence - Saint Peter Hospital | Olympia | Washington | 98506-5166 | — |
| MultiCare Good Samaritan Hospital | Puyallup | Washington | 98372 | — |
| Group Health Cooperative of Puget Sound Oncology Consortium | Seattle | Washington | 98112 | — |
| Group Health Cooperative-Seattle | Seattle | Washington | 98112 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122-4307 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| MultiCare Allenmore Hospital | Tacoma | Washington | 98405 | — |
| Northwest NCI Community Oncology Research Program | Tacoma | Washington | 98405 | — |
| Saint Joseph Medical Center | Tacoma | Washington | 98405 | — |
| Multicare Health System | Tacoma | Washington | 98415 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | — |
| Edwards Comprehensive Cancer Center | Huntington | West Virginia | 25701 | — |
| Langlade Hospital and Cancer Center | Antigo | Wisconsin | 54409 | — |
| Sacred Heart Hospital | Eau Claire | Wisconsin | 54701 | — |
| Midelfort Clinic-Clairemont Campus | Eau Claire | Wisconsin | 54702 | — |
| Aurora Cancer Care-Southern Lakes | Elkhorn | Wisconsin | 53121 | — |
| Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | 54301-3526 | — |
| Saint Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Green Bay Oncology Limited at Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311-6519 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| UW Health Oncology-One South Park | Madison | Wisconsin | 53715 | — |
| Dean Hematology and Oncology Clinic | Madison | Wisconsin | 53717 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
| Holy Family Memorial Hospital | Manitowoc | Wisconsin | 54221 | — |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Vince Lombardi Cancer Clinic-Marinette | Marinette | Wisconsin | 54143 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
| Medical Consultants Limited | Milwaukee | Wisconsin | 53215 | — |
| Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | 54548 | — |
| Green Bay Oncology - Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Green Bay Oncology - Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235 | — |
| Aspirus Regional Cancer Center | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00066690, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 26, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00066690 live on ClinicalTrials.gov.