ClinicalTrials.gov record
Triptorelin With Either Exemestane or Tamoxifen in Treating Premenopausal Women With Hormone-Responsive Breast Cancer
ClinicalTrials.gov ID: NCT00066703
Public ClinicalTrials.gov record NCT00066703. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Trial Evaluating The Role Of Exemestane Plus GnRH Analogue As Adjuvant Therapy For Premenopausal Women With Endocrine Responsive Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using triptorelin, exemestane, and tamoxifen may fight breast cancer by blocking the use of estrogen. It is not yet known whether giving triptorelin together with exemestane is more effective than triptorelin and tamoxifen in treating hormone-responsive breast cancer. PURPOSE: This randomized phase III trial is studying triptorelin and exemestane to see how well they work compared to triptorelin and tamoxifen in treating premenopausal women with hormone-responsive breast cancer.
Study identification
- NCT ID
- NCT00066703
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,672 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 3, 2003 (Actual)
- Primary completion
- Mar 11, 2011 (Actual)
- Completion
- Oct 23, 2024 (Actual)
- Last update posted
- Feb 6, 2026
2003 – 2024
United States locations
- U.S. sites
- 139
- U.S. states
- 30
- U.S. cities
- 109
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center | Burbank | California | 91505 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Providence Holy Cross Cancer Center | Mission Hills | California | 91346-9600 | — |
| Desert Regional Medical Center Comprehensive Cancer Center | Palm Springs | California | 92262 | — |
| Sutter Cancer Center at Roseville Medical Center | Roseville | California | 95661 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| Ruby L. Golleher Cancer Program at Presbyterian Intercommunity Hospital | Whittier | California | 90602 | — |
| University of Colorado Cancer Center at UC Health Sciences Center | Aurora | Colorado | 80045 | — |
| Shaw Regional Cancer Center | Edwards | Colorado | 81632 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Front Range Cancer Specialists | Fort Collins | Colorado | 80528 | — |
| Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center | Farmington | Connecticut | 06360-2875 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5001 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Mountain States Tumor Institute at St. Luke's Regional Medical Center | Boise | Idaho | 83712 | — |
| Kootenai Cancer Center - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | — |
| Resurrection Medical Center | Chicago | Illinois | 60631 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Decatur Memorial Hospital Cancer Care Institute | Decatur | Illinois | 62526 | — |
| Evanston Hospital | Evanston | Illinois | 60201-1781 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Elkhart Clinic, LLC | Elkhart | Indiana | 46514-2098 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Fort Wayne Medical Oncology and Hematology | Fort Wayne | Indiana | 46845 | — |
| Howard Community Hospital | Kokomo | Indiana | 46904 | — |
| Center for Cancer Therapy at LaPorte Hospital and Health Services | La Porte | Indiana | 46350 | — |
| Saint Joseph Regional Medical Center | Mishawaka | Indiana | 46545-1470 | — |
| CCOP - Northern Indiana CR Consortium | South Bend | Indiana | 46601 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Michiana Hematology-Oncology, PC - South Bend | South Bend | Indiana | 46601 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | 51101 | — |
| Cancer Center of Kansas, PA - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas, PA - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas, PA - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas-Independence | Independence | Kansas | 67301 | — |
| Cancer Center of Kansas, PA - Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas, PA - Newton | Newton | Kansas | 67114 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Cancer Center of Kansas, PA - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas, PA - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas, PA - Salina | Salina | Kansas | 67401 | — |
| Shawnee Mission Medical Center | Shawnee Mission | Kansas | 66204 | — |
| Cotton-O'Neil Cancer Center | Topeka | Kansas | 66606 | — |
| Cancer Center of Kansas, PA - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Womens Health, PA - North Review | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Wichita | Wichita | Kansas | 67214 | — |
| CCOP - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas, PA - Winfield | Winfield | Kansas | 67156 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Suburban Hospital | Bethesda | Maryland | 20814 | — |
| Frederick Memorial Hospital Regional Cancer Therapy Center | Frederick | Maryland | 21701 | — |
| Tufts Medical Center Cancer Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Bethke Cancer Center at Emerson Hospital | Concord | Massachusetts | 01742 | — |
| Addison Gilbert Hospital | Gloucester | Massachusetts | 01930 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| NSMC Cancer Center - Peabody | Peabody | Massachusetts | 01960 | — |
| MidMichigan Medical Center - Midland | Midland | Michigan | 48670 | — |
| William Beaumont Hospital - Royal Oak Campus | Royal Oak | Michigan | 48073 | — |
| Lakeland Regional Cancer Care Center - St. Joseph | Saint Joseph | Michigan | 49085 | — |
| Lakeside Cancer Specialists, PLLC | Saint Joseph | Michigan | 49085 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Mercy and Unity Cancer Center at Unity Hospital | Fridley | Minnesota | 55432 | — |
| HealthEast Cancer Care at St. John's Hospital | Maplewood | Minnesota | 55109 | — |
| Virginia Piper Cancer Institute at Abbott - Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center - Minneapolis | Minneapolis | Minnesota | 55415 | — |
| Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center | Robbinsdale | Minnesota | 55422-2900 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Cancer Center | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital Cancer Care Center | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Truman Medical Center - Hospital Hill | Kansas City | Missouri | 64108 | — |
| Saint Luke's Cancer Institute at Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| St. Joseph Medical Center | Kansas City | Missouri | 64114 | — |
| North Kansas City Hospital | Kansas City | Missouri | 64116 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| Saint Louis University Cancer Center | St Louis | Missouri | 63110 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St Louis | Missouri | 63110 | — |
| Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center | Grand Island | Nebraska | 68803 | — |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | 68198-6805 | — |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | Marlton | New Jersey | 08053 | — |
| Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare | Vineland | New Jersey | 08360 | — |
| Fox Chase Virtua Health Cancer Program at Virtua West Jersey | Voorhees Township | New Jersey | 08043 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| NYU Cancer Institute at New York University Medical Center | New York | New York | 10016 | — |
| Our Lady of Mercy Medical Center Comprehensive Cancer Center | The Bronx | New York | 10466 | — |
| Randolph Hospital | Asheboro | North Carolina | 27203-5400 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801 | — |
| Hope A Women's Cancer Center | Asheville | North Carolina | 28816 | — |
| Moses Cone Regional Cancer Center at Wesley Long Community Hospital | Greensboro | North Carolina | 27403-1198 | — |
| Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Kinston Medical Specialists | Kinston | North Carolina | 28501 | — |
| Annie Penn Cancer Center | Reidsville | North Carolina | 27320 | — |
| Aultman Cancer Center at Aultman Hospital | Canton | Ohio | 44710-1799 | — |
| MetroHealth Cancer Care Center at MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Geisinger Cancer Institute at Geisinger Health | Danville | Pennsylvania | 17822-0001 | — |
| Geisinger Hazleton Cancer Center | Hazleton | Pennsylvania | 18201 | — |
| Geisinger Medical Group - Scenery Park | State College | Pennsylvania | 16801 | — |
| Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| Medical X-Ray Center, PC | Sioux Falls | South Dakota | 57105 | — |
| Sanford Cancer Center at Sanford USD Medical Center | Sioux Falls | South Dakota | 57117-5039 | — |
| Erlanger Cancer Center at Erlanger Hospital - Baroness | Chattanooga | Tennessee | 37403 | — |
| West Tennessee Cancer Center at Jackson-Madison County General Hospital | Jackson | Tennessee | 38301 | — |
| Doctor's Hospital of Laredo | Laredo | Texas | 78041 | — |
| Mountainview Medical | Berlin Corners | Vermont | 05602 | — |
| Fletcher Allen Health Care - University Health Center Campus | Burlington | Vermont | 05401 | — |
| Madigan Army Medical Center - Tacoma | Tacoma | Washington | 98431 | — |
| Mary Babb Randolph Cancer Center at West Virginia University Hospitals | Morgantown | West Virginia | 26506 | — |
| Langlade Memorial Hospital | Antigo | Wisconsin | 54409 | — |
| Aurora Memorial Hospital of Burlington | Burlington | Wisconsin | 53105 | — |
| Oncology Alliance - Franklin | Franklin | Wisconsin | 53132 | — |
| Oncology Alliance, SC - Milwaukee - East | Glendale | Wisconsin | 53212-1038 | — |
| Oncology Alliance - Kenosha South | Kenosha | Wisconsin | 53143 | — |
| Aurora Advanced Healthcare East Mequon Clinic | Mequon | Wisconsin | 53092 | — |
| Columbia-Saint Mary's Hospital-Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia Saint Mary's Water Tower Medical Commons Milwaukee | Mequon | Wisconsin | 53211 | — |
| Oncology Alliance, SC - Milwaukee - South | Milwaukee | Wisconsin | 53215 | — |
| Aurora Health Center - Racine | Racine | Wisconsin | 53406-5661 | — |
| Aurora Health Center - Waukesha | Waukesha | Wisconsin | 53188 | — |
| University of Wisconcin Cancer Center at Aspirus Wausau Hospital | Wausau | Wisconsin | 54401 | — |
| Oncology Alliance, SC - Milwaukee - West | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 89 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00066703, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 6, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00066703 live on ClinicalTrials.gov.