Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions
Public ClinicalTrials.gov record NCT00067080. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open Label, Phase II Study on Safety and Efficacy of Long Term Treatment of ICL670 Relative to Deferoxamine in Sickle Cell Disease Patients With Transfusional Hemosiderosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if the new orally active iron chelator, ICL670, is as safe as deferoxamine in preventing accumulation of iron in the body while a patient is undergoing repeated blood transfusions.
Study identification
- NCT ID
- NCT00067080
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 195 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2003 (Type not available)
- Primary completion
- Jul 2007 (Actual)
- Completion
- Not listed
- Last update posted
- Aug 22, 2017
Started 2003
United States locations
- U.S. sites
- 34
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| U. of S. Alabama Medical Center | Mobile | Alabama | 36604 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| Children's Hospital & Research Center | Oakland | California | 94609 | — |
| Colorado Sickle Cell Treatment and Research Center | Denver | Colorado | 80262 | — |
| Howard University Hospital | Washington D.C. | District of Columbia | 20059 | — |
| Tampa Children's Hospital at St Joseph's | Tampa | Florida | 33607 | — |
| Georgia Comprehensive Sickle cell Center, Grady Hospital | Atlanta | Georgia | 30335 | — |
| Adult Sickle Cell Clinic, Medical College of Georgia | Augusta | Georgia | 30912 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital | Chicago | Illinois | 60614 | — |
| Tulane University Sickle Cell Center | New Orleans | Louisiana | 70112 | — |
| Children's Hospital, Department of Hematology/Oncology | New Orleans | Louisiana | 70118 | — |
| Children's Hospital Boston, Division of Hematology/Oncology | Boston | Massachusetts | 02115 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| NY Methodist Hospital | Brooklyn | New York | 11215 | — |
| Weill Medical College of Cornell University | New York | New York | 10021 | — |
| U. Of Rochester Medical Center | Rochester | New York | 14642 | — |
| Sickle Cell Center, Montefiore Hospital | The Bronx | New York | 10467 | — |
| Wake Forest University School of Medicine | Winston-Salem | North Carolina | 27106 | — |
| Barrett Center, University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| James Cancer Hospital | Columbus | Ohio | 43210 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Liberty Hematology Oncology Center | Columbia | South Carolina | 29203 | — |
| Palmetto Health Clinical Trials | Columbia | South Carolina | 29203 | — |
| Santee Hematology/Oncology | Sumter | South Carolina | 29150 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Texas Children's Hospital/Baylor College of Medicine | Houston | Texas | 77030 | — |
| Scott and White Memorial Hospital & Clinics | Temple | Texas | 76508 | — |
| Children's Hospital of the King's Daughter | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00067080, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 22, 2017 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00067080 live on ClinicalTrials.gov.